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The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

The study of social networks, and in particular the spread of disease on networks, has attracted considerable recent attention in the physics community. In this paper, we show that a large class of standard epidemiological models, the…

Statistical Mechanics · Physics 2009-11-07 M. E. J. Newman

We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals…

Populations and Evolution · Quantitative Biology 2012-02-14 Artem S. Novozhilov

Epidemiological models are best suitable to model an epidemic if the spread pattern is stationary. To deal with non-stationary patterns and multiple waves of an epidemic, we develop a hybrid model encompassing epidemic modeling, particle…

Machine Learning · Computer Science 2024-02-01 Naresh Kumar , Seba Susan

The success of diffusion probabilistic models in generative tasks, such as text-to-image generation, has motivated the exploration of their application to regression problems commonly encountered in scientific computing and various other…

Machine Learning · Computer Science 2024-08-12 Dule Shu , Amir Barati Farimani

We consider compartmental models in epidemiology. For the study of the divergence of the stochastic model from its corresponding deterministic limit (i.e., the solution of an ODE) for long time horizon, a large deviations principle suggests…

Probability · Mathematics 2015-01-16 Peter Kratz , Etienne Pardoux , Brice Samegni Kepgnou

Continuous-time multi-state survival models can be used to describe health-related processes over time. In the presence of interval-censored times for transitions between the living states, the likelihood is constructed using transition…

Methodology · Statistics 2017-03-24 Robson J. M. Machado , Ardo van den Hout

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

An ultrametric model of epidemic spread of infections based on the classical SIR model is proposed. Ultrametrics on a set of individuals based on theire hierarchical clustering relativly to the average time of infectious contact is…

Physics and Society · Physics 2020-07-21 V. T. Volov , A. P. Zubarev

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

We introduce a kinetic model that couples the movement of a population of individuals with the dynamics of a pathogen in the same population. We consider that transmission occurs when a susceptible and an infectious individual are…

Analysis of PDEs · Mathematics 2026-01-30 Carolina Strecht-Fernandes , Fabio A. C. C. Chalub

Since social interactions have been shown to lead to symmetric clusters, we propose here that symmetries play a key role in epidemic modeling. Mathematical models on d-ary tree graphs were recently shown to be particularly effective for…

Populations and Evolution · Quantitative Biology 2019-05-24 Laura P. Schaposnik , Anlin Zhang

This study introduces a novel model that effectively captures asymmetric structures in multivariate contingency tables with ordinal categories. Leveraging the principle of maximum entropy, our approach employs f-divergence to provide a…

Methodology · Statistics 2025-12-22 Hisaya Okahara , Kouji Tahata

Multidimensional continuous-time Markov jump processes $(Z(t))$ on $\mathbb{Z}^p$ form a usual set-up for modeling $SIR$-like epidemics. However, when facing incomplete epidemic data, inference based on $(Z(t))$ is not easy to be achieved.…

Methodology · Statistics 2014-01-03 Romain Guy , Catherine Larédo , Elisabeta Vergu

Heterogeneity is an important property of any population experiencing a disease. Here we apply general methods of the theory of heterogeneous populations to the simplest mathematical models in epidemiology. In particular, an SIR…

Populations and Evolution · Quantitative Biology 2012-02-28 Artem S Novozhilov

We introduce a model for the spreading of epidemics by long-range infections and investigate the critical behaviour at the spreading transition. The model generalizes directed bond percolation and is characterized by a probability…

Statistical Mechanics · Physics 2009-10-31 Haye Hinrichsen , Martin Howard

The majority of research on epidemics relies on models which are formulated in continuous-time. However, real-world epidemic data is gathered and processed in a digital manner, which is more accurately described by discrete-time epidemic…

Optimization and Control · Mathematics 2021-07-23 Bastian Prasse , Piet Van Mieghem

The COronaVIrus Disease 2019 (COVID-19) pandemic that has had the world in its grip from the beginning of 2020, has resulted in an unprecedented level of public interest and media attention on the field of mathematical epidemiology. Ever…

Other Quantitative Biology · Quantitative Biology 2022-03-25 Sitabhra Sinha

This paper gives an introduction to rule-based modelling applied to topics in infectious diseases. Rule-based models generalise reaction-based models with reagents that have internal state and may be bound together to form complexes, as in…

Populations and Evolution · Quantitative Biology 2021-08-10 William Waites , Matteo Cavaliere , David Manheim , Jasmina Panovska-Griffiths , Vincent Danos

We consider linear age-structured population equations with diffusion. Supposing maximal regularity of the diffusion operator, we characterize the generator and its spectral properties of the associated strongly continuous semigroup. In…

Analysis of PDEs · Mathematics 2012-01-13 Christoph Walker
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