English
Related papers

Related papers: Explainable Deep Learning Framework for SERS Bio-q…

200 papers

The extensive use of pesticides and synthetic dyes poses critical threats to food safety, human health, and environmental sustainability, necessitating rapid and reliable detection methods. Raman spectroscopy offers molecularly specific…

Materials Science · Physics 2025-11-18 Quach Thi Thai Binh , Thuan Phuoc , Xuan Hai , Thang Bach Phan , Vu Thi Hanh Thu , Nguyen Tuan Hung

Soils have potential to mitigate climate change by sequestering carbon from the atmosphere, but the soil carbon cycle remains poorly understood. Scientists have developed process-based models of the soil carbon cycle based on existing…

Machine Learning · Computer Science 2026-01-27 Joshua Fan , Haodi Xu , Feng Tao , Md Nasim , Marc Grimson , Yiqi Luo , Carla P. Gomes

Accurate segmentation of brain tumors is vital for diagnosis, surgical planning, and treatment monitoring. Deep learning has advanced on benchmarks, but two issues limit clinical use: no uncertainty estimates for errors and no segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Andrew Zhou

Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in thus needed to understand the cell's working mechanism, and…

Quantitative Methods · Quantitative Biology 2011-02-21 Fantine Mordelet , Jean-Philippe Vert

Functional groups and moieties are chemical descriptors of biomolecules that can be used to interpret their properties and functions, leading to the understanding of chemical or biological mechanisms. These chemical building blocks, or…

Biomolecules · Quantitative Biology 2021-11-08 Yasemin Yesiltepe , Ryan S. Renslow , Thomas O. Metz

Medical image super-resolution (MedSR) is essential for improving diagnostic precision across diverse imaging modalities such as MRI, CT, X-ray, Ultrasound, and Fundus imaging. Despite rapid advances in deep learning, challenges remain in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Subhash Gurappa , Trivikram Satharasi , Yashas Hariprasad , Sundararaj Sitharama Iyengar

Hyperspectral stimulated Raman scattering (SRS) microscopy is a label-free technique for biomedical and mineralogical imaging which can suffer from low signal to noise ratios. Here we demonstrate the use of an unsupervised deep learning…

Surface-enhanced Raman scattering (SERS) is a critical tool for chemical sensing and spectroscopy, and a key question is how to optimally design nanostructures for maximizing SERS. We present fundamental limits on spatially-averaged SERS…

Optics · Physics 2025-02-17 Pengning Chao , Ian M. Hammond , Steven G. Johnson

Chiral nanophotonic platforms provide a means of creating near fields with both enhanced asymmetric properties and intensities. They can be exploited for optical measurements that allow enantiomeric discrimination at detection levels…

Multi-sequence MRI is valuable in clinical settings for reliable diagnosis and treatment prognosis, but some sequences may be unusable or missing for various reasons. To address this issue, MRI synthesis is a potential solution. Recent deep…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Luyi Han , Tianyu Zhang , Yunzhi Huang , Haoran Dou , Xin Wang , Yuan Gao , Chunyao Lu , Tan Tao , Ritse Mann

The proliferation of new types of drugs necessitates the urgent development of faster and more accurate detection methods. Traditional detection methods have high requirements for instruments and environments, making the operation complex.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Yongming Li , Peng Wang , Bangdong Han

Recently, the combination of robust one-dimensional convolutional neural networks (1-D CNNs) and Raman spectroscopy has shown great promise in rapid identification of unknown substances with good accuracy. Using this technique, researchers…

Computer Vision and Pattern Recognition · Computer Science 2021-06-11 M. Hamed Mozaffari , Li-Lin Tay

We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jimmy Wu , Bolei Zhou , Diondra Peck , Scott Hsieh , Vandana Dialani , Lester Mackey , Genevieve Patterson

Raman scattering signal can be enhanced through localization of incident field into sub-wavelength hot-spots through plasmonic nano-structures (Surface-enhanced Raman scattering-SERS). Recently, further enhancement of SERS signal via…

This paper introduces an efficient sub-model ensemble framework aimed at enhancing the interpretability of medical deep learning models, thus increasing their clinical applicability. By generating uncertainty maps, this framework enables…

Machine Learning · Computer Science 2024-11-11 Weijie Chen , Alan McMillan

Speech Emotion Recognition (SER) systems often degrade in performance when exposed to the unpredictable acoustic interference found in real-world environments. Additionally, the opacity of deep learning models hinders their adoption in…

Sound · Computer Science 2025-12-23 Sudip Chakrabarty , Pappu Bishwas , Rajdeep Chatterjee

PET imaging is a powerful modality offering quantitative assessments of molecular and physiological processes. The necessity for PET denoising arises from the intrinsic high noise levels in PET imaging, which can significantly hinder the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Siyeop Yoon , Rui Hu , Yuang Wang , Matthew Tivnan , Young-don Son , Dufan Wu , Xiang Li , Kyungsang Kim , Quanzheng Li

Magnetic resonance spectroscopy (MRS) is used to quantify metabolites in vivo and estimate biomarkers for conditions ranging from neurological disorders to cancers. Quantifying low-concentration metabolites such as GABA…

Signal Processing · Electrical Eng. & Systems 2026-02-25 Zien Ma , S. M. Shermer , Oktay Karakuş , Frank C. Langbein

Autonomous Raman instruments on Mars rovers, deep-sea landers, and field robots must interpret raw spectra distorted by fluorescence baselines, peak shifts, and limited ground-truth labels. Using curated subsets of the RRUFF database, we…

Machine Learning · Computer Science 2025-10-01 Deniz Soysal , Xabier García-Andrade , Laura E. Rodriguez , Pablo Sobron , Laura M. Barge , Renaud Detry

In this paper, we revisit techniques for uncertainty estimation within deep neural networks and consolidate a suite of techniques to enhance their reliability. Our investigation reveals that an integrated application of diverse…

Computer Vision and Pattern Recognition · Computer Science 2024-03-04 Yuting Li , Yingyi Chen , Xuanlong Yu , Dexiong Chen , Xi Shen