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Stochastic differential equation mixed-effects models (SDEMEMs) are flexible hierarchical models that are able to account for random variability inherent in the underlying time-dynamics, as well as the variability between experimental units…

Computation · Statistics 2021-01-22 Samuel Wiqvist , Andrew Golightly , Ashleigh T. McLean , Umberto Picchini

AI-driven drug response prediction holds great promise for advancing personalized cancer treatment. However, the inherent heterogenity of cancer and high cost of data generation make accurate prediction challenging. In this study, we…

Machine Learning · Computer Science 2025-05-14 Till Rossner , Ziteng Li , Jonas Balke , Nikoo Salehfard , Tom Seifert , Ming Tang

Drug resistance presents a major challenge in cancer therapy. Single cell profiling offers insights into cellular heterogeneity, yet the application of large-scale foundation models for predicting drug response in single cell data remains…

Artificial Intelligence · Computer Science 2025-05-12 Qing Wang , Yining Pan , Minghao Zhou , Zijia Tang , Yanfei Wang , Guangyu Wang , Qianqian Song

The Convolutional Neural Networks (CNNs) generate the feature representation of complex objects by collecting hierarchical and different parts of semantic sub-features. These sub-features can usually be distributed in grouped form in the…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Xiang Li , Xiaolin Hu , Jian Yang

Single-cell sequencing has a significant role to explore biological processes such as embryonic development, cancer evolution, and cell differentiation. These biological properties can be presented by a two-dimensional scatter plot.…

Genomics · Quantitative Biology 2021-10-19 Ziyi Liu , Minghui Liao , Fulin luo , Bo Du

Monocular depth prediction is an important task in scene understanding. It aims to predict the dense depth of a single RGB image. With the development of deep learning, the performance of this task has made great improvements. However, two…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Feng Xue , Junfeng Cao , Yu Zhou , Fei Sheng , Yankai Wang , Anlong Ming

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Genomics · Quantitative Biology 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

Single-cell RNA sequencing (scRNA-seq) technology enables systematic delineation of cellular states and interactions, providing crucial insights into cellular heterogeneity. Building on this potential, numerous computational methods have…

Genomics · Quantitative Biology 2025-11-11 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Ran Zhang , Gaoyang Li , Hanyu Xie , Jiajia Wang , Yuanchun Zhou , Pengfei Wang

The performance of many network learning applications crucially hinges on the success of network embedding algorithms, which aim to encode rich network information into low-dimensional vertex-based vector representations. This paper…

Machine Learning · Computer Science 2019-10-01 Wenlin Wang , Chenyang Tao , Zhe Gan , Guoyin Wang , Liqun Chen , Xinyuan Zhang , Ruiyi Zhang , Qian Yang , Ricardo Henao , Lawrence Carin

Most image segmentation algorithms are trained on binary masks formulated as a classification task per pixel. However, in applications such as medical imaging, this "black-and-white" approach is too constraining because the contrast between…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Charley Gros , Andreanne Lemay , Julien Cohen-Adad

Most existing federated learning (FL) methods for medical image analysis only considered intramodal heterogeneity, limiting their applicability to multimodal imaging applications. In practice, it is not uncommon that some FL participants…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Qian Dai , Dong Wei , Hong Liu , Jinghan Sun , Liansheng Wang , Yefeng Zheng

Texture, highlights, and shading are some of many visual cues that allow humans to perceive material appearance in single pictures. Yet, recovering spatially-varying bi-directional reflectance distribution functions (SVBRDFs) from a single…

Graphics · Computer Science 2018-10-24 Valentin Deschaintre , Miika Aittala , Fredo Durand , George Drettakis , Adrien Bousseau

Traditional transformer-based semantic segmentation relies on quantized embeddings. However, our analysis reveals that autoencoder accuracy on segmentation mask using quantized embeddings (e.g. VQ-VAE) is 8% lower than continuous-valued…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Masud Ahmed , Zahid Hasan , Syed Arefinul Haque , Abu Zaher Md Faridee , Sanjay Purushotham , Suya You , Nirmalya Roy

Symbolic quick error detection (SQED) has greatly improved efficiency in formal chip verification. However, it has a limitation in detecting single-instruction bugs due to its reliance on the self-consistency property. To address this, we…

Software Engineering · Computer Science 2024-04-09 Yufeng Li , Qiusong Yang , Yiwei Ci , Enyuan Tian

Accurate semantic segmentation models typically require significant computational resources, inhibiting their use in practical applications. Recent works rely on well-crafted lightweight models to achieve fast inference. However, these…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Danna Xue , Fei Yang , Pei Wang , Luis Herranz , Jinqiu Sun , Yu Zhu , Yanning Zhang

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Despite the recent progress in medical image segmentation with scribble-based annotations, the segmentation results of most models are still not ro-bust and generalizable enough in open environments. Evidential deep learn-ing (EDL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Yitong Yang , Xinli Xu , Haigen Hu , Haixia Long , Qianwei Zhou , Qiu Guan

While end-to-end multi-channel electroencephalography (EEG) learning approaches have shown significant promise, their applicability is often constrained in neurological diagnostics, such as intracranial EEG resources. When provided with a…

Machine Learning · Computer Science 2024-10-16 Rikuto Kotoge , Zheng Chen , Tasuku Kimura , Yasuko Matsubara , Takufumi Yanagisawa , Haruhiko Kishima , Yasushi Sakurai

Synthetic Aperture Radar (SAR) imagery plays a critical role in all-weather, day-and-night remote sensing applications. However, existing SAR-oriented deep learning is constrained by data scarcity, while the physically grounded speckle…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Danxu Liu , Di Wang , Hebaixu Wang , Haoyang Chen , Wentao Jiang , Yilin Cheng , Haonan Guo , Wei Cui , Jing Zhang
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