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Clinical management of cancer has continuously evolved for several decades. Biochemical, molecular and genomics approaches have brought and still bring numerous insights into cancerous diseases. It is now accepted that some phenomena,…

Glaucoma is a major eye disease, leading to vision loss in the absence of proper medical treatment. Current diagnosis of glaucoma is performed by ophthalmologists who are often analyzing several types of medical images generated by…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Mijung Kim , Olivier Janssens , Ho-min Park , Jasper Zuallaert , Sofie Van Hoecke , Wesley De Neve

Glaucoma is the leading cause of irreversible blindness worldwide and poses significant diagnostic challenges due to its reliance on subjective evaluation. However, recent advances in computer vision and deep learning have demonstrated the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Mona Ashtari-Majlan , Mohammad Mahdi Dehshibi , David Masip

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

Here, we examine the latest advances in glaucoma detection through Deep Learning (DL) algorithms using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This study focuses on three aspects of DL-based glaucoma…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Mahtab Faraji , Homa Rashidisabet , George R. Nahass , RV Paul Chan , Thasarat S Vajaranant , Darvin Yi

Glaucoma is a chronic eye disease characterized by optic neuropathy, leading to irreversible vision loss. It progresses gradually, often remaining undiagnosed until advanced stages. Early detection is crucial to monitor atrophy and develop…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Sayan Mandal

With the advancements in medical artificial intelligence (AI), fundus image classifiers are increasingly being applied to assist in ophthalmic diagnosis. While existing classification models have achieved high accuracy on specific fundus…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yuzhuo Zhou , Chi Liu , Sheng Shen , Siyu Le , Liwen Yu , Sihan Ouyang , Zongyuan Ge

Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…

Applications · Statistics 2018-05-31 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

The utilization of longitudinal datasets for glaucoma progression prediction offers a compelling approach to support early therapeutic interventions. Predominant methodologies in this domain have primarily focused on the direct prediction…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zhihao Zhao , Junjie Yang , Shahrooz Faghihroohi , Yinzheng Zhao , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

Machine learning (ML) provides a broad spectrum of tools and architectures that enable the transformation of data from simulations and experiments into useful and explainable science, thereby augmenting domain knowledge. Furthermore,…

Plasma Physics · Physics 2024-09-05 Farbod Faraji , Maryam Reza

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

This study introduces the Hybrid Multi-modal VGG (HM-VGG) model, a cutting-edge deep learning approach for the early diagnosis of glaucoma. The HM-VGG model utilizes an attention mechanism to process Visual Field (VF) data, enabling the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Junliang Du , Yiru Cang , Tong Zhou , Jiacheng Hu , Weijie He

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Cheng Huang , Weizheng Xie , Tsengdar Lee , Karanjit Kooner , Ning Zhang , Jia Zhang

The estimation of glaucoma progression is a challenging task as the rate of disease progression varies among individuals in addition to other factors such as measurement variability and the lack of standardization in defining progression.…

Glaucoma is a leading cause of irreversible vision impairment globally and cases are continuously rising worldwide. Early detection is crucial, allowing timely intervention which can prevent further visual field loss. To detect glaucoma,…

Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Daniel Rueckert , Julia A. Schnabel

As a representative optic degenerative condition, glaucoma has been a threat to millions due to its irreversibility and severe impact on human vision fields. Mainly characterized by dimmed and blurred visions, or peripheral vision loss,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Daeyoung Kim
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