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This paper develops a method of biologically guided deep learning for post-radiation FDG-PET image outcome prediction based on pre-radiation images and radiotherapy dose information. Based on the classic reaction-diffusion mechanism, a…

Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-30 Zhe Zhu , Michael Harowicz , Jun Zhang , Ashirbani Saha , Lars J. Grimm , E. Shelley Hwang , Maciej A. Mazurowski

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

Quantitative Methods · Quantitative Biology 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Purpose: Identifying intravenous (IV) contrast use within CT scans is a key component of data curation for model development and testing. Currently, IV contrast is poorly documented in imaging metadata and necessitates manual correction and…

Image and Video Processing · Electrical Eng. & Systems 2021-10-22 Zezhong Ye , Jack M. Qian , Ahmed Hosny , Roman Zeleznik , Deborah Plana , Jirapat Likitlersuang , Zhongyi Zhang , Raymond H. Mak , Hugo J. W. L. Aerts , Benjamin H. Kann

Worldwide, sight loss is commonly occurred by retinal diseases, with age-related macular degeneration (AMD) being a notable facet that affects elderly patients. Approaching 170 million persons wide-ranging have been spotted with AMD, a…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Khaled Al-Saih , Fares Al-Shargie , Mohammed Isam Al-hiyali , Reham Alhejaili

In this work, we propose a Machine Learning model that generates an adjustable 3D dose distribution for external beam radiation therapy for head-and-neck cancer treatments. In contrast to existing Machine Learning methods that provide a…

Purpose: The purpose of the challenge is to find the deep-learning technique for sparse-view CT image reconstruction that can yield the minimum RMSE under ideal conditions, thereby addressing the question of whether or not deep learning can…

Medical Physics · Physics 2022-10-12 Emil Y. Sidky , Xiaochuan Pan

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Mohsen Ghafoorian , Nico Karssemeijer , Tom Heskes , Inge van Uden , Clara Sanchez , Geert Litjens , Frank-Erik de Leeuw , Bram van Ginneken , Elena Marchiori , Bram Platel

Deep learning models have great potential in medical imaging, including orthodontics and skeletal maturity assessment. However, applying a model to data different from its training set can lead to unreliable predictions that may impact…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Omid Halimi Milani , Amanda Nikho , Lauren Mills , Marouane Tliba , Ahmet Enis Cetin , Mohammed H. Elnagar

A central goal in deep learning is to learn compact representations of features at every layer of a neural network, which is useful for both unsupervised representation learning and structured network pruning. While there is a growing body…

Machine Learning · Computer Science 2021-10-05 Jie Bu , Arka Daw , M. Maruf , Anuj Karpatne

The goal of this work is to propose a robust, fast, and fully automatic method for personalized cranial defect reconstruction and implant modeling. We propose a two-step deep learning-based method using a modified U-Net architecture to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-14 Marek Wodzinski , Mateusz Daniol , Miroslaw Socha , Daria Hemmerling , Maciej Stanuch , Andrzej Skalski

Background: Manual delineation of target volumes in head and neck cancer (HNC) remains a significant bottleneck in radiotherapy planning, characterized by high inter-observer variability and time consumption. This study evaluates the…

Although deep learning models for abnormality classification can perform well in screening mammography, the demographic, imaging, and clinical characteristics associated with increased risk of model failure remain unclear. This…

Breast cancer is a highly heterogeneous disease with diverse molecular profiles. The PAM50 gene signature is widely recognized as a standard for classifying breast cancer into intrinsic subtypes, enabling more personalized treatment…

Adaptive radiotherapy is a growing field of study in cancer treatment due to it's objective in sparing healthy tissue. The standard of care in several institutions includes longitudinal cone-beam computed tomography (CBCT) acquisitions to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 William Trung Le , Chulmin Bang , Philippine Cordelle , Daniel Markel , Phuc Felix Nguyen-Tan , Houda Bahig , Samuel Kadoury

Purpose: This study evaluated the out-of-domain performance and generalization capabilities of automated medical image segmentation models, with a particular focus on adaptation to new image acquisitions and disease type. Materials:…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Timothy L. Kline , Sumana Ramanathan , Harrison C. Gottlich , Panagiotis Korfiatis , Adriana V. Gregory

As hospitals move towards automating and integrating their computing systems, more fine-grained hospital operations data are becoming available. These data include hospital architectural drawings, logs of interactions between patients and…

Machine Learning · Computer Science 2023-03-22 Hankyu Jang , Sulyun Lee , D. M. Hasibul Hasan , Philip M. Polgreen , Sriram V. Pemmaraju , Bijaya Adhikari

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Contemporary interventional imaging lacks the real-time 3D guidance needed for the precise localization of mobile thoracic targets. While Cone-Beam CT (CBCT) provides 3D data, it is often too slow for dynamic motion tracking. Deep learning…

Medical Physics · Physics 2025-11-19 Fawazilla Utomo , Tess Reynolds , Nicholas Hindley