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3D shape matching is a long-standing problem in computer vision and computer graphics. While deep neural networks were shown to lead to state-of-the-art results in shape matching, existing learning-based approaches are limited in the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Dongliang Cao , Florian Bernard

Deep neural networks (DNNs) have proven to be highly effective in a variety of tasks, making them the go-to method for problems requiring high-level predictive power. Despite this success, the inner workings of DNNs are often not…

Machine Learning · Statistics 2024-03-04 Anton Thielmann , René-Marcel Kruse , Thomas Kneib , Benjamin Säfken

The survival analysis on histological whole-slide images (WSIs) is one of the most important means to estimate patient prognosis. Although many weakly-supervised deep learning models have been developed for gigapixel WSIs, their potential…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Pei Liu , Luping Ji , Feng Ye , Bo Fu

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Medical image segmentation is a difficult but important task for many clinical operations such as cardiac bi-ventricular volume estimation. More recently, there has been a shift to utilizing deep learning and fully convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Jesse Sun , Fatemeh Darbehani , Mark Zaidi , Bo Wang

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

Predictive modelling is vital to guide preventive efforts. Whilst large-scale prospective cohort studies and a diverse toolkit of available machine learning (ML) algorithms have facilitated such survival task efforts, choosing the…

We propose a novel multimodal deep learning framework for patient-level survival prediction, which integrates whole-slide histology features, RNA-seq expression profiles, and clinical variables. Our architecture combines an ABMIL…

Quantitative Methods · Quantitative Biology 2026-05-15 Hassan Keshvarikhojasteh , Josien P. W. Pluim , Mitko Veta

Explainable artificial intelligence (XAI) is an emerging new domain in which a set of processes and tools allow humans to better comprehend the decisions generated by black box models. However, most of the available XAI tools are often…

Machine Learning · Computer Science 2021-07-22 Zoumpolia Dikopoulou , Serafeim Moustakidis , Patrik Karlsson

Survival analysis is essential for studying time-to-event outcomes and providing a dynamic understanding of the probability of an event occurring over time. Various survival analysis techniques, from traditional statistical models to…

Machine Learning · Computer Science 2024-03-13 Ziwen Wang , Jin Wee Lee , Tanujit Chakraborty , Yilin Ning , Mingxuan Liu , Feng Xie , Marcus Eng Hock Ong , Nan Liu

We propose a novel approach for RGB-D salient instance segmentation using a dual-branch cross-modal feature calibration architecture called CalibNet. Our method simultaneously calibrates depth and RGB features in the kernel and mask…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Jialun Pei , Tao Jiang , He Tang , Nian Liu , Yueming Jin , Deng-Ping Fan , Pheng-Ann Heng

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Model interpretability is crucial for establishing AI safety and clinician trust in medical applications for example, in survival modelling with competing risks. Recent deep learning models have attained very good predictive performance but…

Machine Learning · Computer Science 2026-01-26 Dhanesh Ramachandram , Anne Loefler , Surain Roberts , Amol Verma , Maia Norman , Fahad Razak , Conrad Pow , Charles de Mestral

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Survival analysis is a critical tool for the modelling of time-to-event data, such as life expectancy after a cancer diagnosis or optimal maintenance scheduling for complex machinery. However, current neural network models provide an…

Machine Learning · Statistics 2021-12-06 Fabio Luis de Mello , J Mark Wilkinson , Visakan Kadirkamanathan

The analysis of DNA sequences has become critical in numerous fields, from evolutionary biology to understanding gene regulation and disease mechanisms. While deep neural networks can achieve remarkable predictive performance, they…

Machine Learning · Computer Science 2026-04-15 Nicolas Huynh , Krzysztof Kacprzyk , Ryan Sheridan , David Bentley , Mihaela van der Schaar

Prediction of survival in patients diagnosed with a brain tumour is challenging because of heterogeneous tumour behaviours and responses to treatment. Better estimations of prognosis would support treatment planning and patient support.…

Machine Learning · Computer Science 2021-06-18 Colleen E. Charlton , Michael Tin Chung Poon , Paul M. Brennan , Jacques D. Fleuriot

In explainable artificial intelligence, discriminative feature localization is critical to reveal a blackbox model's decision-making process from raw data to prediction. In this article, we use two real datasets, the MNIST handwritten…

Machine Learning · Statistics 2022-11-21 Ben Dai , Xiaotong Shen , Lin Yee Chen , Chunlin Li , Wei Pan

While machine learning offers diverse techniques suitable for exploring various medical research questions, a cohesive synergistic framework can facilitate the integration and understanding of new approaches within unified model development…

Machine Learning · Computer Science 2025-01-09 Ramtin Zargari Marandi , Anne Svane Frahm , Jens Lundgren , Daniel Dawson Murray , Maja Milojevic