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Although modern imaging technologies allow us to study connectivity between two distinct brain regions in-vivo, an in-depth understanding of how anatomical structure supports brain function and how spontaneous functional fluctuations emerge…

Neurons and Cognition · Quantitative Biology 2024-10-29 Ziquan Wei , Tingting Dan , Jiaqi Ding , Guorong Wu

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

White matter bundle segmentation is a cornerstone of modern tractography to study the brain's structural connectivity in domains such as neurological disorders, neurosurgery, and aging. In this study, we present FIESTA (FIbEr Segmentation…

Accurately identifying white matter tracts in medical images is essential for various applications, including surgery planning and tract-specific analysis. Supervised machine learning models have reached state-of-the-art solving this task…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Robin Peretzke , Klaus Maier-Hein , Jonas Bohn , Yannick Kirchhoff , Saikat Roy , Sabrina Oberli-Palma , Daniela Becker , Pavlina Lenga , Peter Neher

Medical ultrasound provides images which are the spatial map of the tissue echogenicity. Unfortunately, an ultrasound image is a low-quality version of the expected Tissue Reflectivity Function (TRF) mainly due to the non-ideal Point Spread…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sobhan Goudarzi , Hassan Rivaz

We present a geometric framework for aligning white matter fiber tracts. By registering fiber tracts between brains, one expects to see overlap of anatomical structures that often provide meaningful comparisons across subjects. However, the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Andrew Lizarraga , David Lee , Antoni Kubicki , Ashish Sahib , Elvis Nunez , Katherine Narr , Shantanu H. Joshi

Fiber tracking based on diffusion weighted Magnetic Resonance Imaging (dMRI) allows for noninvasive reconstruction of fiber bundles in the human brain. In this chapter, we discuss sources of error and uncertainty in this technique, and…

Computer Vision and Pattern Recognition · Computer Science 2013-07-15 Thomas Schultz , Anna Vilanova , Ralph Brecheisen , Gordon Kindlmann

Designing better deep networks and better reinforcement learning (RL) algorithms are both important for deep RL. This work focuses on the former. Previous methods build the network with several modules like CNN, LSTM and Attention. Recent…

Machine Learning · Computer Science 2023-01-04 Hangyu Mao , Rui Zhao , Hao Chen , Jianye Hao , Yiqun Chen , Dong Li , Junge Zhang , Zhen Xiao

The corticospinal tract (CST) is a critically important white matter fiber tract in the human brain that enables control of voluntary movements of the body. Diffusion MRI tractography is the only method that enables the study of the anatomy…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Jianzhong He , Fan Zhang , Yiang Pan , Yuanjing Feng , Jarrett Rushmore , Erickson Torio , Yogesh Rathi , Nikos Makris , Ron Kikinis , Alexandra J. Golby , Lauren J. O'Donnell

Traumatic brain injury (TBI) disrupts thalamocortical connectivity, contributing to cognitive impairment and post-traumatic epilepsy (PTE). This study presents a novel tractography-based framework that leverages diffusion maps to capture…

Quantitative Methods · Quantitative Biology 2025-10-21 Akul Sharma , Anand A. Joshi , Richard M. Leahy

Tractography traces the peak directions extracted from fiber orientation distribution (FOD) suffering from ambiguous spatial correspondences between diffusion directions and fiber geometry, which is prone to producing erroneous tracks while…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Yuanjing Feng , Lei Xie , Jingqiang Wang , Qiyuan Tian , Jianzhong He , Qingrun Zeng , Fei Gao

As tractography datasets continue to grow in size, there is a need for improved visualization methods that can capture structural patterns occurring in large tractography datasets. Transparency is an increasingly important aspect of finding…

Graphics · Computer Science 2023-08-17 Besm Osman , Mestiez Pereira , Huub van de Wetering , Maxime Chamberland

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Multi-task learning has proven to be effective in improving the performance of correlated tasks. Most of the existing methods use a backbone to extract initial features with independent branches for each task, and the exchange of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Diogo Nunes Goncalves , Jose Marcato Junior , Pedro Zamboni , Hemerson Pistori , Jonathan Li , Keiller Nogueira , Wesley Nunes Goncalves

Learning vector representations for programs is a critical step in applying deep learning techniques for program understanding tasks. Various neural network models are proposed to learn from tree-structured program representations, e.g.,…

Software Engineering · Computer Science 2023-01-10 Wenhan Wang , Kechi Zhang , Ge Li , Shangqing Liu , Anran Li , Zhi Jin , Yang Liu

We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and…

Fraud detection remains a challenging task due to the complex and deceptive nature of fraudulent activities. Current approaches primarily concentrate on learning only one perspective of the graph: either the topological structure of the…

Machine Learning · Computer Science 2025-02-12 Haolin Li , Shuyang Jiang , Lifeng Zhang , Siyuan Du , Guangnan Ye , Hongfeng Chai

In the field of multi-organ medical image segmentation, recent methods frequently employ Transformers to capture long-range dependencies from image features. However, these methods overlook the high computational cost of Transformers and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Dayu Tan , Cheng Kong , Yansen Su , Hai Chen , Dongliang Yang , Junfeng Xia , Chunhou Zheng

Diffusion Tensor Imaging (DTI) tractography offers detailed insights into the structural connectivity of the brain, but presents challenges in effective representation and interpretation in deep learning models. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Vishwa Mohan Singh , Alberto Gaston Villagran Asiares , Luisa Sophie Schuhmacher , Kate Rendall , Simon Weißbrod , David Rügamer , Inga Körte

Recent progress in diffusion MRI and tractography algorithms as well as the launch of the Human Connectome Project (HCP) have provided brain research with an abundance of structural connectivity data. In this work, we describe and evaluate…

Neurons and Cognition · Quantitative Biology 2016-06-02 Kamal Shadi , Saideh Bakhshi , David A. Gutman , Helen S. Mayberg , Constantine Dovrolis