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Pacreatic ductal adenocarcinoma (PDAC) remains one of the most lethal forms of cancer, with a five-year survival rate below 10% primarily due to late detection. This research develops and validates a deep learning framework for early PDAC…

Federated learning (FL) offers a privacy-preserving paradigm for collaborative medical image analysis without sharing raw data. However, the absence of standardized benchmarks for medical image segmentation hinders fair and comprehensive…

Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…

Cancer clinics capture disease data at various scales, from genetic to organ level. Current bioinformatic methods struggle to handle the heterogeneous nature of this data, especially with missing modalities. We propose PARADIGM, a Graph…

Federated Learning has emerged as a promising approach to train machine learning models on decentralized data sources while preserving data privacy. This paper proposes a new federated approach for Naive Bayes (NB) classification, assuming…

In this study, we propose a novel and robust framework, Self-DenseMobileNet, designed to enhance the classification of nodules and non-nodules in chest radiographs (CXRs). Our approach integrates advanced image standardization and…

Deep learning has become a powerful tool for medical image analysis; however, conventional Convolutional Neural Networks (CNNs) often fail to capture the fine-grained and complex features critical for accurate diagnosis. To address this…

ResNet has been widely used in image classification tasks due to its ability to model the residual dependence of constant mappings for linear computation. However, the ResNet method adopts a unidirectional transfer of features and lacks an…

Deep learning models have shown their advantage in many different tasks, including neuroimage analysis. However, to effectively train a high-quality deep learning model, the aggregation of a significant amount of patient information is…

Screening mammography is an important front-line tool for the early detection of breast cancer, and some 39 million exams are conducted each year in the United States alone. Here, we describe a multi-scale convolutional neural network (CNN)…

Federated learning (FL) enables the collaborative training of deep neural networks across decentralized data archives (i.e., clients) without sharing the local data of the clients. Most of the existing FL methods assume that the data…

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…

Federated Learning is the most promising way to train robust Deep Learning models for the segmentation of Covid-19-related findings in chest CTs. By learning in a decentralized fashion, heterogeneous data can be leveraged from a variety of…

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

The ability to accurately estimate risk of developing breast cancer would be invaluable for clinical decision-making. One promising new approach is to integrate image-based risk models based on deep neural networks. However, one must take…

Deep learning (DL) has been increasingly applied in medical imaging, however, it requires large amounts of data, which raises many challenges related to data privacy, storage, and transfer. Federated learning (FL) is a training paradigm…

Content-based mammographic image retrieval systems require exact BIRADS categorical matching across five distinct classes, presenting significantly greater complexity than binary classification tasks commonly addressed in literature.…

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…