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Ordinary differential equation (ODE) is widely used in modeling biological and physical processes in science. In this article, we propose a new reproducing kernel-based approach for estimation and inference of ODE given noisy observations.…

Methodology · Statistics 2021-10-26 Xiaowu Dai , Lexin Li

Mechanistic dynamic models of biochemical networks such as Ordinary Differential Equations (ODEs) contain unknown parameters like the reaction rate constants and the initial concentrations of the compounds. The large number of parameters as…

Data Analysis, Statistics and Probability · Physics 2017-08-14 Clemens Kreutz , Andreas Raue , Jens Timmer

Industrial practitioners now face a bewildering array of possible configurations for effort estimation. How to select the best one for a particular dataset? This paper introduces OIL (short for optimized learning), a novel configuration…

Software Engineering · Computer Science 2018-04-03 Tianpei Xia , Jianfeng Chen , George Mathew , Xipeng Shen , Tim Menzies

Probabilistic models inform an increasingly broad range of business and policy decisions ultimately made by people. Recent algorithmic, computational, and software framework development progress facilitate the proliferation of Bayesian…

Human-Computer Interaction · Computer Science 2022-01-12 Sebastian Stein , John H. Williamson

Stochastic reduced models are an important tool in climate systems whose many spatial and temporal scales cannot be fully discretized or underlying physics may not be fully accounted for. One form of reduced model, the linear inverse model…

Methodology · Statistics 2020-04-29 Dallas Foster , Darin Comeau , Nathan M. Urban

We present the public release of MrMoose, a fitting procedure that is able to perform multi-wavelength and multi-object spectral energy distribution (SED) fitting in a Bayesian framework. This procedure is able to handle a large variety of…

Instrumentation and Methods for Astrophysics · Physics 2018-04-25 Guillaume Drouart , Theresa Falkendal

RooStats is a project to create advanced statistical tools required for the analysis of LHC data, with emphasis on discoveries, confidence intervals, and combined measurements. The idea is to provide the major statistical techniques as a…

Data Analysis, Statistics and Probability · Physics 2011-02-02 Lorenzo Moneta , Kevin Belasco , Kyle Cranmer , Sven Kreiss , Alfio Lazzaro , Danilo Piparo , Gregory Schott , Wouter Verkerke , Matthias Wolf

Over the last decades, the challenges in applied regression and in predictive modeling have been changing considerably: (1) More flexible model specifications are needed as big(ger) data become available, facilitated by more powerful…

Computation · Statistics 2025-10-07 Nikolaus Umlauf , Nadja Klein , Thorsten Simon , Achim Zeileis

Bayesian methods are increasingly being applied to parameterize mechanistic process models used in environmental prediction and forecasting. In particular, models describing ecosystem dynamics with multiple states that are linear and…

Applications · Statistics 2021-10-19 John W. Smith , Leah R. Johnson , Robert Q. Thomas

Differential networks (DN) are important tools for modeling the changes in conditional dependencies between multiple samples. A Bayesian approach for estimating DNs, from the classical viewpoint, is introduced with a computationally…

Methodology · Statistics 2022-04-06 Jarod Smith , Mohammad Arashi , Andriette Bekker

Bayesian penalized regression techniques, such as the Bayesian lasso and the Bayesian horseshoe estimator, have recently received a significant amount of attention in the statistics literature. However, software implementing…

Computation · Statistics 2016-12-21 Enes Makalic , Daniel F. Schmidt

We overview Bayesian estimation, hypothesis testing, and model-averaging and illustrate how they benefit parametric survival analysis. We contrast the Bayesian framework to the currently dominant frequentist approach and highlight…

Methodology · Statistics 2022-09-13 František Bartoš , Frederik Aust , Julia M. Haaf

Joint state and parameter estimation is a core problem for dynamic Bayesian networks. Although modern probabilistic inference toolkits make it relatively easy to specify large and practically relevant probabilistic models, the silver…

Artificial Intelligence · Computer Science 2016-03-31 Yusuf Bugra Erol , Yi Wu , Lei Li , Stuart Russell

The hazard function is central to the formulation of commonly used survival regression models such as the proportional hazards and accelerated failure time models. However, these models rely on a shared baseline hazard, which, when…

Methodology · Statistics 2025-12-19 J. A. Christen , F. J. Rubio

Conformal Inference (CI) is a popular approach for generating finite sample prediction intervals based on the output of any point prediction method when data are exchangeable. Adaptive Conformal Inference (ACI) algorithms extend CI to the…

Computation · Statistics 2023-12-04 Herbert Susmann , Antoine Chambaz , Julie Josse

Online joint estimation of unknown parameters and states in a dynamical system with uncertainty quantification is crucial in many applications. For example, digital twins dynamically update their knowledge of model parameters and states to…

Methodology · Statistics 2026-01-01 Liliang Wang , Alex Gorodetsky

We explain how effective automatic probability density function estimates can be constructed using contemporary Bayesian inference engines such as those based on no-U-turn sampling and expectation propagation. Extensive simulation studies…

Machine Learning · Statistics 2021-09-28 M. P. Wand , J. C. F. Yu

The R package walker extends standard Bayesian general linear models to the case where the effects of the explanatory variables can vary in time. This allows, for example, to model the effects of interventions such as changes in tax policy…

Computation · Statistics 2022-04-13 Jouni Helske

Evaluating forecasts is essential to understand and improve forecasting and make forecasts useful to decision makers. A variety of R packages provide a broad variety of scoring rules, visualisations and diagnostic tools. One particular…

Methodology · Statistics 2024-11-04 Nikos I. Bosse , Hugo Gruson , Anne Cori , Edwin van Leeuwen , Sebastian Funk , Sam Abbott

The Drift-Diffusion Model (DDM) is widely used in neuropsychological studies to understand the decision process by incorporating both reaction times and subjects' responses. Various models have been developed to estimate DDM parameters,…

Applications · Statistics 2025-07-03 Zekai Jin , Yaakov Stern , Seonjoo Lee