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The COVID-19 pandemic underscored a critical need for intervention strategies that balance disease containment with socioeconomic stability. We approach this challenge by designing a framework for modeling and evaluating disease-spread…

Machine Learning · Computer Science 2025-10-07 Marian Chen , Miri Zilka

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

Machine Learning · Statistics 2022-03-08 Swapneel Mehta , Noah Kasmanoff

A COVID-19 vaccine is our best bet for mitigating the ongoing onslaught of the pandemic. However, vaccine is also expected to be a limited resource. An optimal allocation strategy, especially in countries with access inequities and temporal…

The Coronavirus Disease 2019 (COVID-19) pandemic has caused tremendous amount of deaths and a devastating impact on the economic development all over the world. Thus, it is paramount to control its further transmission, for which purpose it…

Applications · Statistics 2021-01-11 Quan-Lin Li , Chengliang Wang , Yiming Xu , Chi Zhang , Yanxia Chang , Xiaole Wu , Zhen-Ping Fan , Zhi-Guo Liu

Many public health threats exist, motivating the need to find optimal intervention strategies. Given the stochastic nature of the threats (e.g., the spread of pandemic influenza, the occurrence of drug overdoses, and the prevalence of…

Optimization and Control · Mathematics 2022-06-29 Zewei Li , James C. Spall

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

Computers and Society · Computer Science 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

Populations and Evolution · Quantitative Biology 2020-06-11 Kok Yew Ng , Meei Mei Gui

As the COVID-19 pandemic continues to devastate globally, one promising field of research is machine learning-driven computer vision to streamline various parts of the COVID-19 clinical workflow. These machine learning methods are typically…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Audrey G. Chung , Maya Pavlova , Hayden Gunraj , Naomi Terhljan , Alexander MacLean , Hossein Aboutalebi , Siddharth Surana , Andy Zhao , Saad Abbasi , Alexander Wong

Mathematical modeling of epidemic spreading has been widely adopted to estimate the threats of epidemic diseases (i.e., the COVID-19 pandemic) as well as to evaluate epidemic control interventions. The indoor place is considered to be a…

Physics and Society · Physics 2022-09-14 Yao Xiao , Mofeng Yang , Zheng Zhu , Hai Yang , Lei Zhang , Sepehr Ghader

With COVID-19 affecting every country globally and changing everyday life, the ability to forecast the spread of the disease is more important than any previous epidemic. The conventional methods of disease-spread modeling, compartmental…

Machine Learning · Statistics 2022-08-19 Benjamin Lucas , Behzad Vahedi , Morteza Karimzadeh

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

The COVID-19 pandemic highlighted the limitations of existing epidemic simulation tools. These tools provide information that guides non-pharmaceutical interventions (NPIs), yet many struggle to capture complex dynamics while remaining…

Multiagent Systems · Computer Science 2026-02-13 Zhijian Gao , Shuxin Li , Bo An

In this work we demonstrate how to automate parts of the infectious disease-control policy-making process via performing inference in existing epidemiological models. The kind of inference tasks undertaken include computing the posterior…

In this work we present a framework which may transform research and praxis in epidemic planning. Introduced in the context of the ongoing COVID-19 pandemic, we provide a concrete demonstration of the way algorithms may learn from…

Machine Learning · Computer Science 2022-10-06 Sekou L. Remy , Oliver E. Bent

Epiabm is a fully tested, open-source software package for epidemiological agent-based modelling, re-implementing the well-known CovidSim model from the MRC Centre for Global Infectious Disease Analysis at Imperial College London. It has…

The Covid-19 outbreak of 2020 has required many governments to develop and adopt mathematical-statistical models of the pandemic for policy and planning purposes. To this end, this work provides a tutorial on building a compartmental model…

Applications · Statistics 2023-09-13 Elizabeth B Amona , Ryad A Ghanam , Edward L Boone , Indranil Sahoo , Laith J Abu-Raddad

Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

Populations and Evolution · Quantitative Biology 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao