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Related papers: A General Pipeline for Glomerulus Whole-Slide Imag…

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Modern medical image segmentation methods primarily use discrete representations in the form of rasterized masks to learn features and generate predictions. Although effective, this paradigm is spatially inflexible, scales poorly to…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Yejia Zhang , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Computer-assisted quantitative analysis on Giga-pixel pathology images has provided a new avenue in histology examination. The innovations have been largely focused on cancer pathology (i.e., tumor segmentation and characterization). In…

Image and Video Processing · Electrical Eng. & Systems 2022-03-24 Ruining Deng , Quan Liu , Can Cui , Zuhayr Asad , Haichun Yang , Yuankai Huo

Accurate liver segmentation in multi-phase MRI is vital for liver fibrosis assessment, yet labeled data is often scarce and unevenly distributed across imaging modalities and vendor systems. We propose a label-efficient segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Quang-Khai Bui-Tran , Minh-Toan Dinh , Thanh-Huy Nguyen , Ba-Thinh Lam , Mai-Anh Vu , Ulas Bagci

Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Yi Zheng , Rushin H. Gindra , Emily J. Green , Eric J. Burks , Margrit Betke , Jennifer E. Beane , Vijaya B. Kolachalama

Glomeruli are histological structures of the kidney cortex formed by interwoven blood capillaries, and are responsible for blood filtration. Glomerular lesions impair kidney filtration capability, leading to protein loss and metabolic waste…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Paulo Chagas , Luiz Souza , Ikaro Araújo , Nayze Aldeman , Angelo Duarte , Michele Angelo , Washington LC dos-Santos , Luciano Oliveira

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

The classification of glomerular lesions is a routine and essential task in renal pathology. Recently, machine learning approaches, especially deep learning algorithms, have been used to perform computer-aided lesion characterization of…

Quantitative Methods · Quantitative Biology 2021-01-20 Yuzhe Lu , Haichun Yang , Zheyu Zhu , Ruining Deng , Agnes B. Fogo , Yuankai Huo

Background: The use of whole slide imaging (WSI) for digital pathology has recently been cleared for primary diagnosis in the US. A conventional WSI system scans the tissue slide to different positions and acquires the digital images. In a…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Shaowei Jiang , Zichao Bian , Xizhi Huang , Pengming Song , He Zhang , Yongbing Zhang , Guoan Zheng

Nasotracheal intubation (NTI) is a critical clinical procedure for establishing and maintaining patient airway patency. Machine-assisted NTI has emerged as a pivotal approach for optimizing procedural efficiency and minimizing manual…

Image and Video Processing · Electrical Eng. & Systems 2026-05-01 Yang Zhou , Chaoyong Zhang , Ruoyi Hao , Huilin Pan , Yang Zhang , Hongliang Ren

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Haoming Luo , Xiaotian Yu , Shengxuming Zhang , Jiabin Xia , Yang Jian , Yuning Sun , Liang Xue , Mingli Song , Jing Zhang , Xiuming Zhang , Zunlei Feng

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

We present a novel diffusion-based approach to generate synthetic histopathological Whole Slide Images (WSIs) at an unprecedented gigapixel scale. Synthetic WSIs have many potential applications: They can augment training datasets to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Robert Harb , Thomas Pock , Heimo Müller

Whole slide images (WSIs) in computational pathology (CPath) pose a major computational challenge due to their gigapixel scale, often requiring the processing of tens to hundreds of thousands of high-resolution patches per slide. This…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Yonghan Shin , SeungKyu Kim , Won-Ki Jeong

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

In this paper, we introduce a simple, yet powerful pipeline for medical image segmentation that combines Fully Convolutional Networks (FCNs) with Fully Convolutional Residual Networks (FC-ResNets). We propose and examine a design that takes…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Michal Drozdzal , Gabriel Chartrand , Eugene Vorontsov , Lisa Di Jorio , An Tang , Adriana Romero , Yoshua Bengio , Chris Pal , Samuel Kadoury

The last decade has seen significant advances in computer-aided diagnostics for cytological screening, mainly through the improvement and integration of scanning techniques such as whole slide imaging (WSI) and the combination with deep…

Signal Processing · Electrical Eng. & Systems 2026-01-23 Philip Groult , Julia D. Sistermanns , Ellen Emken , Oliver Hayden , Wolfgang Utschick

Mycosis fungoides (MF) is a rare, potentially life threatening skin disease, which in early stages clinically and histologically strongly resembles Eczema, a very common and benign skin condition. In order to increase the survival rate, one…

Image and Video Processing · Electrical Eng. & Systems 2020-09-14 Jérémy Scheurer , Claudio Ferrari , Luis Berenguer Todo Bom , Michaela Beer , Werner Kempf , Luis Haug

In digital pathology, the traditional method for deep learning-based image segmentation typically involves a two-stage process: initially segmenting high-resolution whole slide images (WSI) into smaller patches (e.g., 256x256, 512x512,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Yucheng Tang , Yufan He , Vishwesh Nath , Pengfeig Guo , Ruining Deng , Tianyuan Yao , Quan Liu , Can Cui , Mengmeng Yin , Ziyue Xu , Holger Roth , Daguang Xu , Haichun Yang , Yuankai Huo
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