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Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

Computation and Language · Computer Science 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

Prompt tuning is a technology that tunes a small set of parameters to steer a pre-trained language model (LM) to directly generate the output for downstream tasks. Recently, prompt tuning has demonstrated its storage and computation…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-02 Kai-Wei Chang , Yu-Kai Wang , Hua Shen , Iu-thing Kang , Wei-Cheng Tseng , Shang-Wen Li , Hung-yi Lee

Prompt tuning, a parameter- and data-efficient transfer learning paradigm that tunes only a small number of parameters in a model's input space, has become a trend in the vision community since the emergence of large vision-language models…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Yuhang Zang , Wei Li , Kaiyang Zhou , Chen Huang , Chen Change Loy

In light of the growing proportion of older individuals in our society, the timely diagnosis of Alzheimer's disease has become a crucial aspect of healthcare. In this paper, we propose a non-invasive and cost-effective detection method…

Human-Computer Interaction · Computer Science 2025-01-03 Tian Zheng , Xurong Xie , Xiaolan Peng , Hui Chen , Feng Tian

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

Machine Learning · Computer Science 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

Speech contains information that is clinically relevant to some diseases, which has the potential to be used for health assessment. Recent work shows an interest in applying deep learning algorithms, especially pretrained large speech…

Sound · Computer Science 2024-07-02 Hok-Shing Lau , Mark Huntly , Nathon Morgan , Adesua Iyenoma , Biao Zeng , Tim Bashford

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Speech production is a complex phenomenon, wherein the brain orchestrates a sequence of processes involving thought processing, motor planning, and the execution of articulatory movements. However, this intricate execution of various…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-06 Shakeel Ahmad Sheikh

Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…

Computation and Language · Computer Science 2024-04-09 Jonathan Crawford

Compared to other clinical screening techniques, speech-and-language-based automated Alzheimer's disease (AD) detection methods are characterized by their non-invasiveness, cost-effectiveness, and convenience. Previous studies have…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-10 Yin-Long Liu , Rui Feng , Jia-Hong Yuan , Zhen-Hua Ling

Automatic pathological speech detection approaches yield promising results in identifying various pathologies. These approaches are typically designed and evaluated for phonetically-controlled speech scenarios, where speakers are prompted…

Machine Learning · Computer Science 2024-06-17 Shakeel A. Sheikh , Ina Kodrasi

Advancements in spoken language technologies for neurodegenerative speech disorders are crucial for meeting both clinical and technological needs. This overview paper is vital for advancing the field, as it presents a comprehensive review…

Audio and Speech Processing · Electrical Eng. & Systems 2025-08-08 Shakeel A. Sheikh , Md. Sahidullah , Ina Kodrasi

Most of medical developments require the ability to identify samples that are anomalous with respect to a target group or control group, in the sense they could belong to a new, previously unseen class or are not class data. In this case…

Speech representations learned from Self-supervised learning (SSL) models can benefit various speech processing tasks. However, utilizing SSL representations usually requires fine-tuning the pre-trained models or designing task-specific…

Audio and Speech Processing · Electrical Eng. & Systems 2022-07-12 Kai-Wei Chang , Wei-Cheng Tseng , Shang-Wen Li , Hung-yi Lee

The detection of pathologies from speech features is usually defined as a binary classification task with one class representing a specific pathology and the other class representing healthy speech. In this work, we train neural networks,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-02 Dominik Wagner , Ilja Baumann , Franziska Braun , Sebastian P. Bayerl , Elmar Nöth , Korbinian Riedhammer , Tobias Bocklet

Parkinson's Disease (PD) affects over 10 million people worldwide, with speech impairments in up to 89% of patients. Current speech-based detection systems analyze entire utterances, potentially overlooking the diagnostic value of specific…

Computation and Language · Computer Science 2025-10-07 Ilias Tougui , Mehdi Zakroum , Mounir Ghogho

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

State of the art speech enhancement (SE) models achieve strong performance on neurotypical speech, but their effectiveness is substantially reduced for pathological speech. In this paper, we investigate strategies to address this gap for…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-24 Mingchi Hou , Ante Jukic , Ina Kodrasi

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani
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