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State-of-the-art object detection and segmentation methods for microscopy images rely on supervised machine learning, which requires laborious manual annotation of training data. Here we present a self-supervised method based on time arrow…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Benjamin Gallusser , Max Stieber , Martin Weigert

Cell detection is the task of detecting the approximate positions of cell centroids from microscopy images. Recently, convolutional neural network-based approaches have achieved promising performance. However, these methods require a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Kazuya Nishimura , Hyeonwoo Cho , Ryoma Bise

Deep learning (DL) finds rich applications in the wireless domain to improve spectrum awareness. Typically, DL models are either randomly initialized following a statistical distribution or pretrained on tasks from other domains in the form…

Networking and Internet Architecture · Computer Science 2022-11-02 Kemal Davaslioglu , Serdar Boztas , Mehmet Can Ertem , Yalin E. Sagduyu , Ender Ayanoglu

Deep learning methods are successfully used in applications pertaining to ubiquitous computing, health, and well-being. Specifically, the area of human activity recognition (HAR) is primarily transformed by the convolutional and recurrent…

Machine Learning · Computer Science 2019-07-30 Aaqib Saeed , Tanir Ozcelebi , Johan Lukkien

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Cell identification within the H&E slides is an essential prerequisite that can pave the way towards further pathology analyses including tissue classification, cancer grading, and phenotype prediction. However, performing such a task using…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Ramin Nakhli , Amirali Darbandsari , Hossein Farahani , Ali Bashashati

Multivariate time-series data in fields like healthcare and industry are informative but challenging due to high dimensionality and lack of labels. Recent self-supervised learning methods excel in learning rich representations without…

Machine Learning · Computer Science 2024-10-22 Ching Chang , Chiao-Tung Chan , Wei-Yao Wang , Wen-Chih Peng , Tien-Fu Chen

Deep learning methods typically depend on the availability of labeled data, which is expensive and time-consuming to obtain. Active learning addresses such effort by prioritizing which samples are best to annotate in order to maximize the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

Image-based cell profiling aims to create informative representations of cell images. This technique is critical in drug discovery and has greatly advanced with recent improvements in computer vision. Inspired by recent developments in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Siran Dai , Qianqian Xu , Peisong Wen , Yang Liu , Qingming Huang

Real-world time-series datasets often violate the assumptions of standard supervised learning for forecasting -- their distributions evolve over time, rendering the conventional training and model selection procedures suboptimal. In this…

Machine Learning · Computer Science 2022-09-27 Sercan O. Arik , Nathanael C. Yoder , Tomas Pfister

Self-supervised learning presents a remarkable performance to utilize unlabeled data for various video tasks. In this paper, we focus on applying the power of self-supervised methods to improve semi-supervised action proposal generation.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-08 Xiang Wang , Shiwei Zhang , Zhiwu Qing , Yuanjie Shao , Changxin Gao , Nong Sang

Recent development in angle-resolved photoemission spectroscopy (ARPES) technique involves spatially resolving samples while maintaining the high-resolution feature of momentum space. This development easily expands the data size and its…

Instrumentation and Detectors · Physics 2023-08-24 Sandy Adhitia Ekahana , Genta Indra Winata , Y. Soh , Gabriel Aeppli , Radovic Milan , Ming Shi

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

Recently, Self-Supervised Representation Learning (SSRL) has attracted much attention in the field of computer vision, speech, natural language processing (NLP), and recently, with other types of modalities, including time series from…

Machine Learning · Computer Science 2022-06-09 Shohreh Deldari , Hao Xue , Aaqib Saeed , Jiayuan He , Daniel V. Smith , Flora D. Salim

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

Machine Learning · Computer Science 2026-05-28 Manuel Dileo , Andrea Sottoriva

The supervised learning paradigm is limited by the cost - and sometimes the impracticality - of data collection and labeling in multiple domains. Self-supervised learning, a paradigm which exploits the structure of unlabeled data to create…

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