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Related papers: Uncertainty Quantification for Clinical Outcome Pr…

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The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Clinician-facing predictive models are increasingly present in the healthcare setting. Regardless of their success with respect to performance metrics, all models have uncertainty. We investigate how to visually communicate uncertainty in…

Human-Computer Interaction · Computer Science 2022-10-25 Caitlin F. Harrigan , Gabriela Morgenshtern , Anna Goldenberg , Fanny Chevalier

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Quantifying uncertainty in black-box LLMs is vital for reliable responses and scalable oversight. Existing methods, which gauge a model's uncertainty through evaluating self-consistency in responses to the target query, can be misleading:…

Computation and Language · Computer Science 2025-10-22 Yu Feng , Phu Mon Htut , Zheng Qi , Wei Xiao , Manuel Mager , Nikolaos Pappas , Kishaloy Halder , Yang Li , Yassine Benajiba , Dan Roth

Applications of large language models often involve the generation of free-form responses, in which case uncertainty quantification becomes challenging. This is due to the need to identify task-specific uncertainties (e.g., about the…

Computation and Language · Computer Science 2024-10-21 Ziyu Wang , Chris Holmes

Large language models(LLMs) are increasingly expanding their real-world applications across domains, e.g., question answering, autonomous driving, and automatic software development. Despite this achievement, LLMs, as data-driven systems,…

Artificial Intelligence · Computer Science 2025-12-09 Xianzong Wu , Xiaohong Li , Lili Quan , Qiang Hu

There has been much recent interest in evaluating large language models for uncertainty calibration to facilitate model control and modulate user trust. Inference time uncertainty, which may provide a real-time signal to the model or…

Computation and Language · Computer Science 2025-08-12 Kyle Moore , Jesse Roberts , Daryl Watson

Large language models (LLMs) have shown promising performance across various tasks. However, their autoregressive decoding process poses significant challenges for efficient deployment on existing AI hardware. Quantization alleviates memory…

Machine Learning · Computer Science 2025-12-01 Guanxi Lu , Hao Mark Chen , Zhiqiang Que , Wayne Luk , Hongxiang Fan

Despite demonstrating impressive capabilities, Large Language Models (LLMs) still often struggle to accurately express the factual knowledge they possess, especially in cases where the LLMs' knowledge boundaries are ambiguous. To improve…

Computation and Language · Computer Science 2025-05-26 Boyang Xue , Fei Mi , Qi Zhu , Hongru Wang , Rui Wang , Sheng Wang , Erxin Yu , Xuming Hu , Kam-Fai Wong

The recent convergence of pervasive computing and machine learning has given rise to numerous services, impacting almost all areas of economic and social activity. However, the use of AI techniques precludes certain standard software…

Software Engineering · Computer Science 2025-12-11 Vladimir Balditsyn , Philippe Lalanda , German Vega , Stéphanie Chollet

Large language model (LLM) agents are increasingly deployed in structured biomedical data environments, yet they often produce fluent but overconfident outputs when reasoning over complex multi-table data. We introduce an uncertainty-aware…

Vision-Language Models like GPT-4, LLaVA, and CogVLM have surged in popularity recently due to their impressive performance in several vision-language tasks. Current evaluation methods, however, overlook an essential component: uncertainty,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Vasily Kostumov , Bulat Nutfullin , Oleg Pilipenko , Eugene Ilyushin

Conversation forecasting tasks a model with predicting the outcome of an unfolding conversation. For instance, it can be applied in social media moderation to predict harmful user behaviors before they occur, allowing for preventative…

Computation and Language · Computer Science 2024-10-22 Anthony Sicilia , Malihe Alikhani

Advances in the general capabilities of large language models (LLMs) have led to their use for information retrieval, and as components in automated decision systems. A faithful representation of probabilistic reasoning in these models may…

Artificial Intelligence · Computer Science 2025-04-21 Gabriel Freedman , Francesca Toni

Vision-Language Models (VLMs) have achieved remarkable progress in complex visual understanding across scientific and reasoning tasks. While performance benchmarking has advanced our understanding of these capabilities, the critical…

Artificial Intelligence · Computer Science 2026-01-27 Asif Azad , Mohammad Sadat Hossain , MD Sadik Hossain Shanto , M Saifur Rahman , Md Rizwan Parvez

With increasing deployment of machine learning systems in various real-world tasks, there is a greater need for accurate quantification of predictive uncertainty. While the common goal in uncertainty quantification (UQ) in machine learning…

Machine Learning · Computer Science 2021-09-22 Youngseog Chung , Ian Char , Han Guo , Jeff Schneider , Willie Neiswanger

Large Language Models (LLMs) show promise for natural language generation in healthcare, but risk hallucinating factually incorrect information. Deploying LLMs for medical question answering necessitates reliable uncertainty estimation (UE)…

Computation and Language · Computer Science 2024-07-12 Jiaxin Wu , Yizhou Yu , Hong-Yu Zhou

With the growing adoption of Large Language Models (LLMs) for open-ended tasks, accurately assessing epistemic uncertainty, which reflects a model's lack of knowledge, has become crucial to ensuring reliable outcomes. However, quantifying…

Computation and Language · Computer Science 2025-10-10 Xinyi Liu , Weiguang Wang , Hangfeng He

Guaranteeing the correctness and factuality of language model (LM) outputs is a major open problem. In this work, we propose conformal factuality, a framework that can ensure high probability correctness guarantees for LMs by connecting…

Machine Learning · Computer Science 2024-02-20 Christopher Mohri , Tatsunori Hashimoto
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