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Accurate multi-slice reconstruction from limited measurement data is crucial to speed up the acquisition process in medical and scientific imaging. However, it remains challenging due to the ill-posed nature of the problem and the high…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Laurentius Valdy , Richard D. Paul , Alessio Quercia , Zhuo Cao , Xuan Zhao , Hanno Scharr , Arya Bangun

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Hanyu Chen , Zhixiu Hao , Lin Guo , Liying Xiao

Purpose: To propose a domain-conditioned and temporal-guided diffusion modeling method, termed dynamic Diffusion Modeling (dDiMo), for accelerated dynamic MRI reconstruction, enabling diffusion process to characterize spatiotemporal…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Liping Zhang , Iris Yuwen Zhou , Sydney B. Montesi , Li Feng , Fang Liu

Medical image restoration tasks aim to recover high-quality images from degraded observations, exhibiting emergent desires in many clinical scenarios, such as low-dose CT image denoising, MRI super-resolution, and MRI artifact removal.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Pengcheng Zheng , Kecheng Chen , Jiaxin Huang , Bohao Chen , Ju Liu , Yazhou Ren , Xiaorong Pu

Instead of performing text-conditioned denoising in the image domain, latent diffusion models (LDMs) operate in latent space of a variational autoencoder (VAE), enabling more efficient processing at reduced computational costs. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Jason Becker , Chris Wendler , Peter Baylies , Robert West , Christian Wressnegger

Magnetic resonance imaging (MRI) reconstruction is an active inverse problem which can be addressed by conventional compressed sensing (CS) MRI algorithms that exploit the sparse nature of MRI in an iterative optimization-based manner.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Yuxiang Dai , Peixian Zhuang

We address the problem of recovering a time-varying 4D distribution from a sparse sequence of 2D projections - analogous to novel-view synthesis from sparse cameras, but applied to the 4D transverse phase space density $\rho(x,p_x,y,p_y)$…

Accelerator Physics · Physics 2026-04-08 Alexander Scheinker , Alexander Plastun , Peter Ostroumov

Low-field magnetic resonance imaging (MRI) offers affordable access to diagnostic imaging but faces challenges such as prolonged acquisition times and reduced image quality. Although accelerated imaging via k-space undersampling helps…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Daniel Tweneboah Anyimadu , Mohammed M. Abdelsamea , Ahmed Karam Eldaly

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

This paper presents novel single and multi-shell sampling schemes for diffusion MRI. In diffusion MRI, it is paramount that the number of samples is as small as possible in order that scan times are practical in a clinical setting. The…

Signal Processing · Electrical Eng. & Systems 2019-02-01 Alice P. Bates , Zubair Khalid , Jason D. McEwen , Rodney A. Kennedy , Alessandro Daducci , Erick J. Canales-Rodríguez

Diffusion Probabilistic Models (DPMs) have demonstrated significant potential in 3D medical image segmentation tasks. However, their high computational cost and inability to fully capture global 3D contextual information limit their…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Kangbo Ma

Magnetic Resonance (MR) image reconstruction from under-sampled acquisition promises faster scanning time. To this end, current State-of-The-Art (SoTA) approaches leverage deep neural networks and supervised training to learn a recovery…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Cheng Peng , Pengfei Guo , S. Kevin Zhou , Vishal Patel , Rama Chellappa

MRI synthesis promises to mitigate the challenge of missing MRI modality in clinical practice. Diffusion model has emerged as an effective technique for image synthesis by modelling complex and variable data distributions. However, most…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Lan Jiang , Ye Mao , Xi Chen , Xiangfeng Wang , Chao Li

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

Ill-posed imaging inverse problems remain challenging due to the ambiguity in mapping degraded observations to clean images. Diffusion-based generative priors have recently shown promise, but typically rely on computationally intensive…

Image and Video Processing · Electrical Eng. & Systems 2026-02-13 Ayush Varshney , Katherine L. Bouman , Berthy T. Feng

This work aims to improve the applicability of diffusion models in realistic image restoration. Specifically, we enhance the diffusion model in several aspects such as network architecture, noise level, denoising steps, training image size,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Ziwei Luo , Fredrik K. Gustafsson , Zheng Zhao , Jens Sjölund , Thomas B. Schön

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

The success of Deep Learning applications critically depends on the quality and scale of the underlying training data. Generative adversarial networks (GANs) can generate arbitrary large datasets, but diversity and fidelity are limited,…

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman