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Diffusion models (DMs) have exhibited remarkable efficacy in various image restoration tasks. However, existing approaches typically operate within the high-dimensional pixel space, resulting in high computational overhead. While methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yang Zheng , Wen Li , Zhaoqiang Liu

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Magnetic resonance imaging (MRI) requires long acquisition times, raising costs, reducing accessibility, and making scans more susceptible to motion artifacts. Diffusion probabilistic models that learn data-driven priors can potentially…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Rohan Sanda , Asad Aali , Andrew Johnston , Eduardo Reis , Gordon Wetzstein , Sara Fridovich-Keil

Diffusion models produce high-quality synthetic data but suffer from slow inference. We propose 3D Variable-Step Denoising Diffusion Probabilistic Model (VS-DDPM) a framework engineered to maintain generative quality while accelerating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Nikoo Moradi , Gijs Luijten , Behrus Hinrichs-Puladi , Jens Kleesiek , Victor Alves , Jan Egger , André Ferreira

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Despite the recent visually-pleasing results achieved, the massive computational cost has been a long-standing flaw for diffusion probabilistic models (DPMs), which, in turn, greatly limits their applications on resource-limited platforms.…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Xingyi Yang , Daquan Zhou , Jiashi Feng , Xinchao Wang

Deep learning-based 3D imaging, in particular magnetic resonance imaging (MRI), is challenging because of limited availability of 3D training data. Therefore, 2D diffusion models trained on 2D slices are starting to be leveraged for 3D MRI…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Anselm Krainovic , Stefan Ruschke , Reinhard Heckel

We present a latent diffusion-based differentiable inversion method (LD-DIM) for PDE-constrained inverse problems involving high-dimensional spatially distributed coefficients. LD-DIM couples a pretrained latent diffusion prior with an…

Numerical Analysis · Mathematics 2025-12-30 Zihan Lin , QiZhi He

Diffusion probabilistic models (DPMs) which employ explicit likelihood characterization and a gradual sampling process to synthesize data, have gained increasing research interest. Despite their huge computational burdens due to the large…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Yuheng Fan , Hanxi Liao , Shiqi Huang , Yimin Luo , Huazhu Fu , Haikun Qi

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

Image rescaling aims to learn the optimal low-resolution (LR) image that can be accurately reconstructed to its original high-resolution (HR) counterpart, providing an efficient image processing and storage method for ultra-high definition…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Ce Wang , Zhenyu Hu , Wanjie Sun , Zhenzhong Chen

Diffusion models have been increasingly used as strong generative priors for solving inverse problems such as super-resolution in medical imaging. However, these approaches typically utilize a diffusion prior trained at a single scale,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Darshan Thaker , Mahmoud Mostapha , Radu Miron , Shihan Qiu , Mariappan Nadar

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Advances in latent diffusion models (LDMs) have revolutionized high-resolution image generation, but the design space of the autoencoder that is central to these systems remains underexplored. In this paper, we introduce LiteVAE, a new…

Machine Learning · Computer Science 2025-01-22 Seyedmorteza Sadat , Jakob Buhmann , Derek Bradley , Otmar Hilliges , Romann M. Weber

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

Detail features of magnetic resonance images play a cru-cial role in accurate medical diagnosis and treatment, as they capture subtle changes that pose challenges for doc-tors when performing precise judgments. However, the widely utilized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Mengxiao Geng , Jiahao Zhu , Xiaolin Zhu , Qiqing Liu , Dong Liang , Qiegen Liu

Existing methods for restoring degraded human-centric images often struggle with insufficient fidelity, particularly in human body restoration (HBR). Recent diffusion-based restoration methods commonly adapt pre-trained text-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jue Gong , Zihan Zhou , Jingkai Wang , Shu Li , Libo Liu , Jianliang Lan , Yulun Zhang

Algorithms for Magnetic Resonance (MR) image reconstruction from undersampled measurements exploit prior information to compensate for missing k-space data. Deep learning (DL) provides a powerful framework for extracting such information…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Kerem C. Tezcan , Christian F. Baumgartner , Roger Luechinger , Klaas P. Pruessmann , Ender Konukoglu

Deep learning has shown the capability to substantially accelerate MRI reconstruction while acquiring fewer measurements. Recently, diffusion models have gained burgeoning interests as a novel group of deep learning-based generative…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Jiahao Huang , Angelica Aviles-Rivero , Carola-Bibiane Schönlieb , Guang Yang

Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. Recently, the deep learning-based MRI reconstruction techniques were suggested to…

Computer Vision and Pattern Recognition · Computer Science 2019-03-20 Ali Pour Yazdanpanah , Onur Afacan , Simon K. Warfield