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The conventional approach to Bayesian decision-theoretic experiment design involves searching over possible experiments to select a design that maximizes the expected value of a specified utility function. The expectation is over the joint…
Model misspecification analysis strategies, such as anomaly detection, model validation, and model comparison are a key component of scientific model development. Over the last few years, there has been a rapid rise in the use of…
We present a novel method for accurately auditing the differential privacy (DP) guarantees of DP mechanisms. In particular, our solution is applicable to auditing DP guarantees of machine learning (ML) models. Previous auditing methods…
Virtual imaging trials (VITs) offer scalable and cost-effective tools for evaluating imaging systems and protocols. However, their translational impact depends on rigorous comparability between virtual and real-world populations. This study…
Large language models (LLMs) are increasingly deployed under diverse numerical precision configurations, including standard floating-point formats (e.g., bfloat16 and float16) and quantized integer formats (e.g., int16 and int8), to meet…
In the causal inference literature an estimator belonging to a class of semi-parametric estimators is called robust if it has desirable properties under the assumption that at least one of the working models is correctly specified. In this…
The conventional way of identifying DNA motifs, solely based on match alignment information, is susceptible to a high number of spurious sites. A novel scoring system has been introduced by taking both match and mismatch alignment…
While many real-world data streams imply that they change frequently in a nonstationary way, most of deep learning methods optimize neural networks on training data, and this leads to severe performance degradation when dataset shift…
When the training and test data are from different distributions, domain adaptation is needed to reduce dataset bias to improve the model's generalization ability. Since it is difficult to directly match the cross-domain joint…
Detecting multimodal misinformation, especially in the form of image-text pairs, is crucial. Obtaining large-scale, high-quality real-world fact-checking datasets for training detectors is costly, leading researchers to use synthetic…
Scientists need to compare the support for models based on observed phenomena. The main goal of the evidential paradigm is to quantify the strength of evidence in the data for a reference model relative to an alternative model. This is done…
Multiple imputation (MI) inference handles missing data by imputing the missing values $m$ times, and then combining the results from the $m$ complete-data analyses. However, the existing method for combining likelihood ratio tests (LRTs)…
Change-point models are widely used by statisticians to model drastic changes in the pattern of observed data. Least squares/maximum likelihood based estimation of change-points leads to curious asymptotic phenomena. When the change-point…
Accurate brain tumor segmentation from MRI scans is critical for diagnosis and treatment planning. Despite the strong performance of recent deep learning approaches, two fundamental limitations remain: (1) the lack of reliable uncertainty…
CDD, or Contamination Detection via output Distribution, identifies data contamination by measuring the peakedness of a model's sampled outputs. We study the conditions under which this approach succeeds and fails on small language models…
Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…
The proliferation of misinformation across diverse social media platforms has drawn significant attention from both academic and industrial communities due to its detrimental effects. Accordingly, automatically distinguishing…
Deep neural networks often produce overconfident predictions, undermining their reliability in safety-critical applications. This miscalibration is further exacerbated under distribution shift, where test data deviates from the training…
Food authenticity studies are concerned with determining if food samples have been correctly labeled or not. Discriminant analysis methods are an integral part of the methodology for food authentication. Motivated by food authenticity…
Deep learning (DL) has shown great potential in digital pathology applications. The robustness of a diagnostic DL-based solution is essential for safe clinical deployment. In this work we evaluate if adding uncertainty estimates for DL…