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Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

The healthcare environment is commonly referred to as "information-rich" but also "knowledge poor". Healthcare systems collect huge amounts of data from various sources: lab reports, medical letters, logs of medical tools or programs,…

Computation and Language · Computer Science 2024-01-22 Elena-Simona Apostol , Ciprian-Octavian Truică

Large Language Models (LLMs) have demonstrated impressive capabilities in language generation and general task performance. However, their application to spoken language understanding (SLU) remains challenging, particularly for token-level…

Computation and Language · Computer Science 2025-10-09 Shangjian Yin , Peijie Huang , Jiatian Chen , Haojing Huang , Yuhong Xu

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Mental disorders are clinically significant patterns of behavior that are associated with stress and/or impairment in social, occupational, or family activities. People suffering from such disorders are often misjudged and poorly diagnosed…

Machine Learning · Computer Science 2025-09-03 Abu Shad Ahammed , Sayeri Mukherjee , Roman Obermaisser

Large language models (LLMs) have demonstrated impressive capabilities in language tasks, but they require high computing power and rely on static knowledge. To overcome these limitations, Retrieval-Augmented Generation (RAG) incorporates…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-17 Jiaxing Li , Chi Xu , Lianchen Jia , Feng Wang , Cong Zhang , Jiangchuan Liu

Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…

Computation and Language · Computer Science 2025-06-12 Yao Xiao , Heidi Christensen , Stefan Goetze

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Large Language Models (LLMs) have shown promise in various domains, including healthcare, with significant potential to transform mental health applications by enabling scalable and accessible solutions. This study aims to provide a…

Artificial Intelligence · Computer Science 2025-11-25 Abdelrahman Hanafi , Mohammed Saad , Noureldin Zahran , Radwa J. Hanafy , Mohammed E. Fouda

Generalist Large Language Models (LLMs), such as GPT-4, have shown considerable promise in various domains, including medical diagnosis. Rare diseases, affecting approximately 300 million people worldwide, often have unsatisfactory clinical…

Computation and Language · Computer Science 2024-07-08 Xuanzhong Chen , Xiaohao Mao , Qihan Guo , Lun Wang , Shuyang Zhang , Ting Chen

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

Large Language Models (LLMs) offer significant potential for delivering health information. However, their reliability in low-resource contexts remains uncertain. This study evaluates GPT-4, Gemini Pro, Llama~3, and Mistral-7B on health…

Computation and Language · Computer Science 2026-03-24 Mohammed Rakibul Hasan

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Mental health disorders impose a substantial global socioeconomic burden. While large language models (LLMs) offer 24/7, non-judgmental interactions to address this gap, pretrained models lack contextual coherence and emotional alignment…

Computation and Language · Computer Science 2026-02-17 Eric Hua Qing Zhang , Julia Ive

In diagnosing challenging conditions such as Alzheimer's disease (AD), imaging is an important reference. Non-imaging patient data such as patient information, genetic data, medication information, cognitive and memory tests also play a…

Machine Learning · Computer Science 2023-06-01 Yingjie Feng , Jun Wang , Xianfeng Gu , Xiaoyin Xu , Min Zhang

This paper studies the performance of large language models (LLMs), particularly regarding demographic fairness, in solving real-world healthcare tasks. We evaluate state-of-the-art LLMs with three prevalent learning frameworks across six…

Computation and Language · Computer Science 2024-12-10 Yue Zhou , Barbara Di Eugenio , Lu Cheng

Large language models (LLMs) have demonstrated potential in educational applications, yet their capacity to accurately assess the cognitive alignment of reading materials with students' developmental stages remains insufficiently explored.…

Computation and Language · Computer Science 2025-08-26 Wenhan Dong , Zhen Sun , Yuemeng Zhao , Zifan Peng , Jun Wu , Jingyi Zheng , Yule Liu , Xinlei He , Yu Wang , Ruiming Wang , Xinyi Huang , Lei Mo

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang
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