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Spatial transcriptomics reveals gene expression patterns within tissue context, enabling precision oncology applications such as treatment response prediction, but its high cost and technical complexity limit clinical adoption. Predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Won June Cho , Hongjun Yoon , Daeky Jeong , Hyeongyeol Lim , Yosep Chong

Deep learning models are modern tools for spatio-temporal graph (STG) forecasting. Though successful, we argue that data scarcity is a key factor limiting their recent improvements. Meanwhile, contrastive learning has been an effective…

Machine Learning · Computer Science 2022-11-04 Xu Liu , Yuxuan Liang , Chao Huang , Yu Zheng , Bryan Hooi , Roger Zimmermann

Although hyperspectral image (HSI) classification is critical for supporting various environmental applications, it is a challenging task due to the spectral-mixture effect, the spatial-spectral heterogeneity and the difficulty to preserve…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yimin Zhu , Lincoln Linlin Xu

Image clustering, which involves grouping images into different clusters without labels, is a key task in unsupervised learning. Although previous deep clustering methods have achieved remarkable results, they only explore the intrinsic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Haixin Zhang , Yongjun Li , Dong Huang

Fine-grained high-resolution remote sensing mapping typically relies on localized visual features, which restricts cross-domain generalizability and often leads to fragmented predictions of large-scale land covers. While global geospatial…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Jienan Lyu , Miao Yang , Jinchen Cai , Yiwen Hu , Guanyi Lu , Junhao Qiu , Runmin Dong

Accurately determining cell type composition in disease-relevant tissues is crucial for identifying disease targets. Most existing spatial transcriptomics (ST) technologies cannot achieve single-cell resolution, making it challenging to…

Machine Learning · Computer Science 2024-08-12 Lin Huang , Xiaofei Liu , Shunfang Wang , Wenwen Min

Cancer pathological analysis requires modeling tumor heterogeneity across multiple modalities, primarily through transcriptomics and whole slide imaging (WSI), along with their spatial relations. On one hand, bulk transcriptomics and WSI…

Machine Learning · Computer Science 2026-03-17 Jingkun Yu , Guangkai Shang , Changtao Li , Xun Gong , Tianrui Li , Yazhou He , Zhipeng Luo

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

Sleep stage classification is crucial for detecting patients' health conditions. Existing models, which mainly use Convolutional Neural Networks (CNN) for modelling Euclidean data and Graph Convolution Networks (GNN) for modelling…

Machine Learning · Computer Science 2023-09-06 Yuze Liu , Ziming Zhao , Tiehua Zhang , Kang Wang , Xin Chen , Xiaowei Huang , Jun Yin , Zhishu Shen

Spatial omics has transformed our understanding of tissue architecture by preserving spatial context of gene expression patterns. Simultaneously, advances in imaging AI have enabled extraction of morphological features describing the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Eduard Chelebian , Christophe Avenel , Carolina Wählby

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Jiaqi Yang , Wenting Chen , Xiaohan Xing , Sean He , Xiaoling Luo , Xinheng Lyu , Linlin Shen , Guoping Qiu

The technology to generate Spatially Resolved Transcriptomics (SRT) data is rapidly being improved and applied to investigate a variety of biological tissues. The ability to interrogate how spatially localised gene expression can lend new…

Quantitative Methods · Quantitative Biology 2021-08-04 Natalie Charitakis , Mirana Ramialison , Hieu T. Nim

Among various region embedding methods, graph-based region relation learning models stand out, owing to their strong structure representation ability for encoding spatial correlations with graph neural networks. Despite their effectiveness,…

Machine Learning · Computer Science 2023-05-09 Qianru Zhang , Chao Huang , Lianghao Xia , Zheng Wang , Zhonghang Li , Siuming Yiu

Accurate cell type annotation is a crucial step in analyzing single-cell RNA sequencing (scRNA-seq) data, which provides valuable insights into cellular heterogeneity. However, due to the high dimensionality and prevalence of zero elements…

Machine Learning · Computer Science 2025-08-14 Huifa Li , Jie Fu , Xinlin Zhuang , Haolin Yang , Xinpeng Ling , Tong Cheng , Haochen xue , Imran Razzak , Zhili Chen

Computed tomography (CT) imaging could be very practical for diagnosing various diseases. However, the nature of the CT images is even more diverse since the resolution and number of the slices of a CT scan are determined by the machine and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-11 Chih-Chung Hsu , Chi-Han Tsai , Guan-Lin Chen , Sin-Di Ma , Shen-Chieh Tai

Hierarchical clustering recursively partitions data at an increasingly finer granularity. In real-world applications, multi-view data have become increasingly important. This raises a less investigated problem, i.e., multi-view hierarchical…

Machine Learning · Computer Science 2022-05-06 Fangfei Lin , Bing Bai , Kun Bai , Yazhou Ren , Peng Zhao , Zenglin Xu

Multimodal semantic communication has great potential to enhance downstream task performance by integrating complementary information across modalities. This paper introduces ProMSC-MIS, a novel Prompt-based Multimodal Semantic…

Multimedia · Computer Science 2025-08-28 Haoshuo Zhang , Yufei Bo , Meixia Tao

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Self-supervised learning (SSL) approaches have achieved great success when the amount of labeled data is limited. Within SSL, models learn robust feature representations by solving pretext tasks. One such pretext task is contrastive…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Jamshid Hassanpour , Vinkle Srivastav , Didier Mutter , Nicolas Padoy

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

Artificial Intelligence · Computer Science 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong
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