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While tumor dynamic modeling has been widely applied to support the development of oncology drugs, there remains a need to increase predictivity, enable personalized therapy, and improve decision-making. We propose the use of Tumor Dynamic…

Quantitative Methods · Quantitative Biology 2023-10-24 Mark Laurie , James Lu

In this paper, we introduce NNSynth, a new framework that uses machine learning techniques to guide the design of abstraction-based controllers with correctness guarantees. NNSynth utilizes neural networks (NNs) to guide the search over the…

Systems and Control · Electrical Eng. & Systems 2022-04-08 Xiaowu Sun , Yasser Shoukry

Neural differential equations predict the derivative of a stochastic process. This allows irregular forecasting with arbitrary time-steps. However, the expressive temporal flexibility often comes with a high sensitivity to noise. In…

Machine Learning · Computer Science 2023-02-07 Stav Belogolovsky , Ido Greenberg , Danny Eitan , Shie Mannor

There has been a great deal of recent interest in learning and approximation of functions that can be expressed as expectations of a given nonlinearity with respect to its random internal parameters. Examples of such representations include…

Optimization and Control · Mathematics 2022-12-05 Tanya Veeravalli , Maxim Raginsky

Neural differential equations offer a powerful approach for learning dynamics from data. However, they do not impose known constraints that should be obeyed by the learned model. It is well-known that enforcing constraints in surrogate…

Continuous normalizing flows (CNFs) construct invertible mappings between an arbitrary complex distribution and an isotropic Gaussian distribution using Neural Ordinary Differential Equations (neural ODEs). It has not been tractable on…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Shian Du , Yihong Luo , Wei Chen , Jian Xu , Delu Zeng

We propose Fluid Logic, a paradigm in which modal logical reasoning, temporal, epistemic, doxastic, deontic, is lifted from discrete Kripke structures to continuous manifolds via Neural Stochastic Differential Equations (Neural SDEs). Each…

Logic in Computer Science · Computer Science 2026-03-05 Antonin Sulc

Mobile robots, such as ground vehicles and quadrotors, are becoming increasingly important in various fields, from logistics to agriculture, where they automate processes in environments that are difficult to access for humans. However, to…

Robotics · Computer Science 2025-10-08 Shao-Yi Yu , Jen-Wei Wang , Maya Horii , Vikas Garg , Tarek Zohdi

Neural-ODE parameterize a differential equation using continuous depth neural network and solve it using numerical ODE-integrator. These models offer a constant memory cost compared to models with discrete sequence of hidden layers in which…

Machine Learning · Computer Science 2025-03-27 Sheikh Waqas Akhtar

Time-reversal symmetry, which requires that the dynamics of a system should not change with the reversal of time axis, is a fundamental property that frequently holds in classical and quantum mechanics. In this paper, we propose a novel…

Machine Learning · Computer Science 2021-01-08 In Huh , Eunho Yang , Sung Ju Hwang , Jinwoo Shin

We propose a new class of parameterizations for spatio-temporal point processes which leverage Neural ODEs as a computational method and enable flexible, high-fidelity models of discrete events that are localized in continuous time and…

Machine Learning · Computer Science 2021-03-19 Ricky T. Q. Chen , Brandon Amos , Maximilian Nickel

Neural ordinary differential equations (neural ODEs) can effectively learn dynamical systems from time series data, but their behavior on graph-structured data remains poorly understood, especially when applied to graphs with different size…

Physics and Society · Physics 2026-02-10 Moritz Laber , Tina Eliassi-Rad , Brennan Klein

The neural ordinary differential equation (ODE) framework has emerged as a powerful tool for developing accelerated surrogate models of complex physical systems governed by partial differential equations (PDEs). A popular approach for PDE…

Fluid Dynamics · Physics 2025-03-26 Ashish S. Nair , Shivam Barwey , Pinaki Pal , Jonathan F. MacArt , Troy Arcomano , Romit Maulik

Neural ordinary differential equations (NODE) have been recently proposed as a promising approach for nonlinear system identification tasks. In this work, we systematically compare their predictive performance with current state-of-the-art…

Machine Learning · Computer Science 2022-03-16 Aowabin Rahman , Ján Drgoňa , Aaron Tuor , Jan Strube

Many physical AI tasks are governed by implicit equilibrium: an agent actuates a subset of degrees of freedom (boundary DoFs), while the remaining free DoFs settle by minimizing a total potential energy. Even seemingly basic tasks such as…

Robotics · Computer Science 2026-05-06 Dezhong Tong , Jiawen Wang , Hengyi Zhou , Yinglong Shen , Xiaonan Huang , M. Khalid Jawed

Recent research shows that supervised learning can be an effective tool for designing near-optimal feedback controllers for high-dimensional nonlinear dynamic systems. But the behavior of neural network controllers is still not well…

Optimization and Control · Mathematics 2022-10-10 Tenavi Nakamura-Zimmerer , Qi Gong , Wei Kang

Stochastic differential equations (SDEs) are used to describe a wide variety of complex stochastic dynamical systems. Learning the hidden physics within SDEs is crucial for unraveling fundamental understanding of these systems' stochastic…

Machine Learning · Computer Science 2022-07-26 Jared O'Leary , Joel A. Paulson , Ali Mesbah

Neural ordinary differential equations (neural ODEs) have emerged as a novel network architecture that bridges dynamical systems and deep learning. However, the gradient obtained with the continuous adjoint method in the vanilla neural ODE…

Machine Learning · Computer Science 2023-06-12 Hong Zhang , Wenjun Zhao

Operator learning has emerged as a promising paradigm for developing efficient surrogate models to solve partial differential equations (PDEs). However, existing approaches often overlook the domain knowledge inherent in the underlying PDEs…

Machine Learning · Computer Science 2025-10-20 Ziqian Li , Kang Liu , Yongcun Song , Hangrui Yue , Enrique Zuazua

Stochastic differential equations (SDEs) are a staple of mathematical modelling of temporal dynamics. However, a fundamental limitation has been that such models have typically been relatively inflexible, which recent work introducing…

Machine Learning · Computer Science 2021-05-12 Patrick Kidger , James Foster , Xuechen Li , Harald Oberhauser , Terry Lyons
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