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In genetic association studies, detecting phenotype-genotype association is a primary goal. We assume that the relationship between the data -phenotype, genetic markers and environmental covariates - can be modelled by a generalized linear…

Methodology · Statistics 2020-04-13 K. K. Halle , Ø. Bakke , S. Djurovic , A. Bye , E. Ryeng , U. Wisløff , O. A. Andreassen , M. Langaas

The privacy protection mechanism of federated learning (FL) offers an effective solution for cross-center medical collaboration and data sharing. In multi-site medical image segmentation, each medical site serves as a client of FL, and its…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Fubao Zhu , Yanhui Tian , Chuang Han , Yanting Li , Jiaofen Nan , Ni Yao , Weihua Zhou

Convolutional neural networks (CNNs) provide flexible function approximations for a wide variety of applications when the input variables are in the form of images or spatial data. Although CNNs often outperform traditional statistical…

Methodology · Statistics 2024-05-24 Yeseul Jeon , Won Chang , Seonghyun Jeong , Sanghoon Han , Jaewoo Park

Personalized medication aims to tailor healthcare to individual patient characteristics. However, the heterogeneity of patient data across healthcare systems presents significant challenges to achieving accurate and effective personalized…

Artificial Intelligence · Computer Science 2024-12-10 Jiechao Gao , Yuangang Li

Finite mixture distributions arise in sampling a heterogeneous population. Data drawn from such a population will exhibit extra variability relative to any single subpopulation. Statistical models based on finite mixtures can assist in the…

Methodology · Statistics 2024-01-19 Andrew M. Raim , Nagaraj K. Neerchal , Jorge G. Morel

Linear mixed models are able to handle an extraordinary range of complications in regression-type analyses. Their most common use is to account for within-subject correlation in longitudinal data analysis. They are also the standard vehicle…

Statistics Theory · Mathematics 2007-06-13 Y. Zhao , J. Staudenmayer , B. A. Coull , M. P. Wand

Generalized linear models (GLMs) are popular for data-analysis in almost all quantitative sciences, but the choice of likelihood family and link function is often difficult. This motivates the search for likelihoods and links that minimize…

Methodology · Statistics 2024-03-19 Maximilian Scholz , Paul-Christian Bürkner

A recent literature in econometrics models unobserved cross-sectional heterogeneity in panel data by assigning each cross-sectional unit a one-dimensional, discrete latent type. Such models have been shown to allow estimation and inference…

Econometrics · Economics 2020-01-31 Max Cytrynbaum

Heterogeneous federated learning (HtFL) aims to enable collaboration among clients that differ in both data distributions and model architectures. Prototype-based methods, which communicate class-level feature centers (prototypes) instead…

Artificial Intelligence · Computer Science 2026-05-08 Xinghao Wu , Jianwei Niu , Guogang Zhu , Xuefeng Liu , Shaojie Tang , Jiayuan Zhang

We pursue tractable Bayesian analysis of generalized linear models (GLMs) for categorical data. Thus far, GLMs are difficult to scale to more than a few dozen categories due to non-conjugacy or strong posterior dependencies when using…

Machine Learning · Statistics 2022-06-02 Michael T. Wojnowicz , Shuchin Aeron , Eric L. Miller , Michael C. Hughes

Federated learning (FL) is an emerging paradigm that permits a large number of clients with heterogeneous data to coordinate learning of a unified global model without the need to share data amongst each other. A major challenge in…

Machine Learning · Computer Science 2023-11-16 Irene Tenison , Sai Aravind Sreeramadas , Vaikkunth Mugunthan , Edouard Oyallon , Irina Rish , Eugene Belilovsky

As Large Language Models (LLMs) become increasingly powerful and accessible to human users, ensuring fairness across diverse demographic groups, i.e., group fairness, is a critical ethical concern. However, current fairness and bias…

Computation and Language · Computer Science 2025-03-12 Kefan Song , Jin Yao , Runnan Jiang , Rohan Chandra , Shangtong Zhang

With the evolution of large language models (LLMs), their robustness against individual simple biases has been enhanced. However, we observe that the ensemble of multiple simple biases still exerts a significant adverse impact on LLMs.…

Computation and Language · Computer Science 2026-04-21 Zhouhao Sun , Zhiyuan Kan , Xiao Ding , Li Du , Bibo Cai , Yang Zhao , Bing Qin , Ting Liu

Although understanding and characterizing causal effects have become essential in observational studies, it is challenging when the confounders are high-dimensional. In this article, we develop a general framework $\textit{CausalEGM}$ for…

Machine Learning · Statistics 2023-03-20 Qiao Liu , Zhongren Chen , Wing Hung Wong

This paper presents a novel nonlinear regression model for estimating heterogeneous treatment effects from observational data, geared specifically towards situations with small effect sizes, heterogeneous effects, and strong confounding.…

Methodology · Statistics 2019-11-14 P. Richard Hahn , Jared S. Murray , Carlos Carvalho

When using the finite element method (FEM) in inverse problems, its discretization error can produce parameter estimates that are inaccurate and overconfident. The Bayesian finite element method (BFEM) provides a probabilistic model for the…

Numerical Analysis · Mathematics 2026-01-26 Anne Poot , Iuri Rocha , Pierre Kerfriden , Frans van der Meer

Exposure to diverse non-genetic factors, known as the exposome, is a critical determinant of health outcomes. However, analyzing the exposome presents significant methodological challenges, including: high collinearity among exposures, the…

Methodology · Statistics 2025-10-10 Matteo Amestoy , Mark van de Wiel , Jeroen Lakerveld , Wessel van Wieringen

Estimating heterogeneous treatment effects (HTEs) is crucial for precision medicine. While multiple studies can improve the generalizability of results, leveraging them for estimation is statistically challenging. Existing approaches often…

Methodology · Statistics 2025-12-22 Cathy Shyr , Boyu Ren , Prasad Patil , Giovanni Parmigiani

Estimating causal effect using machine learning (ML) algorithms can help to relax functional form assumptions if used within appropriate frameworks. However, most of these frameworks assume settings with cross-sectional data, whereas…

Econometrics · Economics 2024-09-04 Jonathan Fuhr , Dominik Papies

Multimodal Large Language Models (MLLMs) have recently been explored as face verification systems that determine whether two face images are of the same person. Unlike dedicated face recognition systems, MLLMs approach this task through…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Ünsal Öztürk , Hatef Otroshi Shahreza , Sébastien Marcel