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Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

The success of deep learning methods in medical image segmentation tasks heavily depends on a large amount of labeled data to supervise the training. On the other hand, the annotation of biomedical images requires domain knowledge and can…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Xinrong Hu , Dewen Zeng , Xiaowei Xu , Yiyu Shi

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Labeling of multivariate biomedical time series data is a laborious and expensive process. Self-supervised contrastive learning alleviates the need for large, labeled datasets through pretraining on unlabeled data. However, for multivariate…

Machine Learning · Statistics 2023-07-21 Thea Brüsch , Mikkel N. Schmidt , Tommy S. Alstrøm

Datasets for biosignals, such as electroencephalogram (EEG) and electrocardiogram (ECG), often have noisy labels and have limited number of subjects (<100). To handle these challenges, we propose a self-supervised approach based on…

Machine Learning · Computer Science 2020-07-10 Joseph Y. Cheng , Hanlin Goh , Kaan Dogrusoz , Oncel Tuzel , Erdrin Azemi

There is an increasing number of medical use-cases where classification algorithms based on deep neural networks reach performance levels that are competitive with human medical experts. To alleviate the challenges of small dataset sizes,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Vignesh Srinivasan , Nils Strodthoff , Jackie Ma , Alexander Binder , Klaus-Robert Müller , Wojciech Samek

Pre-training a recognition model with contrastive learning on a large dataset of unlabeled data has shown great potential to boost the performance of a downstream task, e.g., image classification. However, in domains such as medical…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Jizong Peng , Ping Wang , Chrisitian Desrosiers , Marco Pedersoli

The self-supervised ultrasound (US) video model pretraining can use a small amount of labeled data to achieve one of the most promising results on US diagnosis. However, it does not take full advantage of multi-level knowledge for learning…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Chunhui Zhang , Yixiong Chen , Li Liu , Qiong Liu , Xi Zhou

Traditional supervised learning with deep neural networks requires a tremendous amount of labelled data to converge to a good solution. For 3D medical images, it is often impractical to build a large homogeneous annotated dataset for a…

Deep learning techniques have revolutionised medical imaging, improving diagnostic accuracy and enabling both more accurate and earlier disease detection. However, the relationship between pre-training strategies and downstream performance…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Felix Krones

Deep neural networks (DNNs) have achieved remarkable success in computer vision tasks such as image classification, segmentation, and object detection. However, they are vulnerable to adversarial attacks, which can cause incorrect…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Suklav Ghosh , Sonal Kumar , Arijit Sur

Deep learning has demonstrated significant improvements in medical image segmentation using a sufficiently large amount of training data with manual labels. Acquiring well-representative labels requires expert knowledge and exhaustive…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Jinxi Xiang , Zhuowei Li , Wenji Wang , Qing Xia , Shaoting Zhang

Pre-trained language models have proven their unique powers in capturing implicit language features. However, most pre-training approaches focus on the word-level training objective, while sentence-level objectives are rarely studied. In…

Computation and Language · Computer Science 2021-01-01 Zhuofeng Wu , Sinong Wang , Jiatao Gu , Madian Khabsa , Fei Sun , Hao Ma

Supervised deep learning needs a large amount of labeled data to achieve high performance. However, in medical imaging analysis, each site may only have a limited amount of data and labels, which makes learning ineffective. Federated…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Yawen Wu , Dewen Zeng , Zhepeng Wang , Yiyu Shi , Jingtong Hu

Recent advances in image-text pretraining have significantly enhanced visual understanding by aligning visual and textual representations. Contrastive Language-Image Pretraining (CLIP) has played a pivotal role in multimodal learning.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Zihan Li , Yiqing Wang , Sina Farsiu , Paul Kinahan

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

Chromosome recognition is an essential task in karyotyping, which plays a vital role in birth defect diagnosis and biomedical research. However, existing classification methods face significant challenges due to the inter-class similarity…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ruijia Chang , Suncheng Xiang , Chengyu Zhou , Kui Su , Dahong Qian , Jun Wang

Self-supervised contrastive learning between pairs of multiple views of the same image has been shown to successfully leverage unlabeled data to produce meaningful visual representations for both natural and medical images. However, there…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Yen Nhi Truong Vu , Richard Wang , Niranjan Balachandar , Can Liu , Andrew Y. Ng , Pranav Rajpurkar