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Cluster randomization trials commonly employ multiple endpoints. When a single summary of treatment effects across endpoints is of primary interest, global hypothesis testing/effect estimation methods represent a common analysis strategy.…

Methodology · Statistics 2025-05-19 E. Davies Smith , V. Jairath , G. Zou

We propose a kinetic model for understanding the link between opinion formation phenomena and epidemic dynamics. The recent pandemic has brought to light that vaccine hesitancy can present different phases and temporal and spatial…

Physics and Society · Physics 2023-10-31 Andrea Bondesan , Giuseppe Toscani , Mattia Zanella

We develop a model of infection spread that takes into account the existence of a vulnerable group as well as the variability of the social relations of individuals. We develop a compartmentalized power-law model, with power-law connections…

Physics and Society · Physics 2020-10-13 Simone Santini

In order to meet regulatory approval, pharmaceutical companies often must demonstrate that new vaccines reduce the total risk of a post-infection outcome like transmission, symptomatic disease, severe illness, or death in randomized,…

Methodology · Statistics 2024-09-23 Rob Trangucci , Yang Chen , Jon Zelner

This paper develops a model of \textit{identification design} and applies it to robust causal inference in microeconometrics. The decision maker observes the population distribution of signals generated by an information structure and ranks…

Theoretical Economics · Economics 2026-04-20 Maxwell Rosenthal

Estimating vaccination uptake is an integral part of ensuring public health. It was recently shown that vaccination uptake can be estimated automatically from web data, instead of slowly collected clinical records or population surveys. All…

Information Retrieval · Computer Science 2017-02-24 Niels Dalum Hansen , Kåre Mølbak , Ingemar J. Cox , Christina Lioma

As algorithmic decision-making systems become more prevalent in society, ensuring the fairness of these systems is becoming increasingly important. Whilst there has been substantial research in building fair algorithmic decision-making…

Machine Learning · Computer Science 2023-10-30 Madeleine Waller , Odinaldo Rodrigues , Oana Cocarascu

Vaccination and outbreak monitoring are essential tools for preventing and minimizing outbreaks of infectious diseases. Targeted strategies, where the individuals most important for monitoring or preventing outbreaks are selected for…

Physics and Society · Physics 2016-03-04 Enys Mones , Arkadiusz Stopczynski , Alex Pentland , Nathaniel Hupert , Sune Lehmann

The response of the immune system to different vaccination patterns is studied with a simple model. It is argued that the history and characteristics of the pattern defines very different secondary immune responses in the case of infection.…

Other Quantitative Biology · Quantitative Biology 2009-11-10 P. Etchegoin

Preferences of individuals are distributions of elements generated by generalized functions. Models of economic decision-making derived from such distributions are consistent with results of physiological experiments, and explain any…

Neurons and Cognition · Quantitative Biology 2012-01-20 Leonid A. Shapiro

Biological organisms have evolved a wide range of immune mechanisms to defend themselves against pathogens. Beyond molecular details, these mechanisms differ in how protection is acquired, processed and passed on to subsequent generations…

Populations and Evolution · Quantitative Biology 2016-12-26 Andreas Mayer , Thierry Mora , Olivier Rivoire , Aleksandra M. Walczak

Human decision-making differs due to variation in both incentives and available information. This constitutes a substantial challenge for the evaluation of whether and how machine learning predictions can improve decision outcomes. We…

General Economics · Economics 2020-11-24 Michael Allan Ribers , Hannes Ullrich

In designing an intelligent system that must be able to explain its reasoning to a human user, or to provide generalizations that the human user finds reasonable, it may be useful to take into consideration psychological data on what types…

Artificial Intelligence · Computer Science 2013-04-15 James E. Corter , Mark A. Gluck

Consider the causal effect that one individual's treatment may have on another individual's outcome when the outcome is contagious, with specific application to the effect of vaccination on an infectious disease outcome. The effect of one…

Methodology · Statistics 2014-03-06 Elizabeth L. Ogburn , Tyler J. VanderWeele

Infectious diseases are still a major global burden for modern society causing 13 million deaths annually. One way to reduce the morbidity and mortality rates from infectious diseases is through preventative or targeted vaccinations.…

Social and Information Networks · Computer Science 2021-01-27 Md Shahzamal , Raja Jurdak , Bernard Mans , Frank de Hoog , Dean Paini

Heterogeneity is a dominant factor in the behaviour of many biological processes. Despite this, it is common for mathematical and statistical analyses to ignore biological heterogeneity as a source of variability in experimental data.…

If we can lower the number of people needed to vaccinate for a community to be immune against contagious diseases, we can save resources and life. A key to reach such a lower threshold of immunization is to find and vaccinate people who,…

Populations and Evolution · Quantitative Biology 2012-10-10 Sungmin Lee , Luis E. C. Rocha , Fredrik Liljeros , Petter Holme

Targeting and personalization policies can be used to improve outcomes beyond the uniform policy that assigns the best performing treatment in an A/B test to everyone. Personalization relies on the presence of heterogeneity of treatment…

Applications · Statistics 2025-12-12 Anya Shchetkina

Interval identification of parameters such as average treatment effects, average partial effects and welfare is particularly common when using observational data and experimental data with imperfect compliance due to the endogeneity of…

Econometrics · Economics 2025-04-09 Sukjin Han , Adam McCloskey

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

Quantitative Methods · Quantitative Biology 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss