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Brain metastases are a common complication of systemic cancer, affecting over 20% of patients with primary malignancies. Longitudinal magnetic resonance imaging (MRI) is essential for diagnosing patients, tracking disease progression,…

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Ipek Oguz , Honghai Zhang , Milan Sonka

Knee Osteoarthritis (OA) is a debilitating disease affecting over 250 million people worldwide. Currently, radiologists grade the severity of OA on an ordinal scale from zero to four using the Kellgren-Lawrence (KL) system. Recent studies…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Niamh Belton , Misgina Tsighe Hagos , Aonghus Lawlor , Kathleen M. Curran

The Electron Paramagnetic Spectroscopy (EPR) is the most direct and powerful method for the detection and identification of free radicals and other species with unpaired electrons. Statistics disorders are a common gynaecological disorder…

Limited DXA access hinders osteoporosis screening. This proof-of-concept study proposes using widely available knee X-rays for opportunistic Bone Mineral Density (BMD) estimation via deep learning, emphasizing robust uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Long Hui , Wai Lok Yeung

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

Background: MR-based subchondral bone effectively predicts knee osteoarthritis. However, its clinical application is limited by the cost and time of MR. Purpose: We aim to develop a novel distillation-learning-based method named SRRD for…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Yuqi Hu , Xiangyu Zhao , Gaowei Qing , Kai Xie , Chenglei Liu , Lichi Zhang

Cardiac Magnetic Resonance (CMR) imaging is widely used for heart model reconstruction and digital twin computational analysis because of its ability to visualize soft tissues and capture dynamic functions. However, CMR images have an…

Many statistical machine approaches could ultimately highlight novel features of the etiology of complex diseases by analyzing multi-omics data. However, they are sensitive to some deviations in distribution when the observed samples are…

Machine Learning · Statistics 2022-01-14 Md Ashad Alam , Hui Shen , Hong-Wen Deng

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Minkyu Jeon , Rishwanth Raghu , Miro Astore , Geoffrey Woollard , Ryan Feathers , Alkin Kaz , Sonya M. Hanson , Pilar Cossio , Ellen D. Zhong

Objective assessment of Magnetic Resonance Imaging (MRI) scans of osteoarthritis (OA) can address the limitation of the current OA assessment. Segmentation of bone, cartilage, and joint fluid is necessary for the OA objective assessment.…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Jacob L. Jaremko , Janet L. Ronsky

Electronic health records (EHR) data have considerable variability in data completeness across sites and patients. Lack of "EHR data-continuity" or "EHR data-discontinuity", defined as "having medical information recorded outside the reach…

Unilateral limb motor imagery (MI) plays an important role in upper-limb motor rehabilitation and precise control of external devices, and places higher demands on spatial resolution. However, most existing public datasets focus on binary-…

Human-Computer Interaction · Computer Science 2026-02-05 Lufeng Feng , Baomin Xu , Haoran Zhang , Bihai Lin , Zuxuan Deng , Sidi Tao , Chenyu Liu , Shifan Jia , Li Duan , Ziyu Jia

The University of California San Francisco Brain Metastases Stereotactic Radiosurgery (UCSF-BMSR) dataset is a public, clinical, multimodal brain MRI dataset consisting of 560 brain MRIs from 412 patients with expert annotations of 5136…

Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used…

Quantitative Methods · Quantitative Biology 2021-07-22 Albee Y. Ling , Allison W. Kurian , Jennifer L. Caswell-Jin , George W. Sledge , Nigam H. Shah , Suzanne R. Tamang

Background. Osteoarthritis affects about 528 million people worldwide, causing pain and stiffness in the joints. Arthroplasty is commonly performed to treat joint osteoarthritis, reducing pain and improving mobility. Nevertheless, a…

Knee injuries are frequent, varied and often require the patient to undergo intensive rehabilitation for several months. Treatment protocols usually contemplate some recurrent measurements in order to assess progress, such as goniometry.…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 João Bernardino , Luís Filipe Teixeira , Hugo Sereno Ferreira

Knee Osteoarthritis (KOA) is a prevalent musculoskeletal disorder that severely impacts mobility and quality of life, particularly among older adults. Its diagnosis often relies on subjective assessments using the Kellgren-Lawrence (KL)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Zhe Wang , Aladine Chetouani , Yung Hsin Chen , Yuhua Ru , Fang Chen , Mohamed Jarraya , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane

Clinical diagnosis of meniscus injuries requires radiologists to integrate volumetric MRI evidence with patient context (e.g., sex, age, BMI) and to produce structured diagnostic reports. Existing knee MRI benchmarks are typically unimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Shurui Xu , Siqi Yang , Weiping Ding , Hui Wang , Mengzhen Fan , Yuyu Sun , Shuyan Li