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Image denoising is a fundamental task in computer vision, particularly in medical ultrasound (US) imaging, where speckle noise significantly degrades image quality. Although recent advancements in deep neural networks have led to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuesong Li , Nassir Navab , Zhongliang Jiang

Significant progress has been made in self-supervised image denoising (SSID) in the recent few years. However, most methods focus on dealing with spatially independent noise, and they have little practicality on real-world sRGB images with…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Junyi Li , Zhilu Zhang , Xiaoyu Liu , Chaoyu Feng , Xiaotao Wang , Lei Lei , Wangmeng Zuo

Recent studies on learning-based image denoising have achieved promising performance on various noise reduction tasks. Most of these deep denoisers are trained either under the supervision of clean references, or unsupervised on synthetic…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Rui Zhao , Daniel P. K. Lun , Kin-Man Lam

Deep learning has revolutionized medical imaging, but its effectiveness is severely limited by insufficient labeled training data. This paper introduces a novel GAN-based semi-supervised learning framework specifically designed for low…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Guido Manni , Clemente Lauretti , Loredana Zollo , Paolo Soda

We propose a novel self-supervised image blind denoising approach in which two neural networks jointly predict the clean signal and infer the noise distribution. Assuming that the noisy observations are independent conditionally to the…

Machine Learning · Computer Science 2021-02-17 Jean Ollion , Charles Ollion , Elisabeth Gassiat , Luc Lehéricy , Sylvain Le Corff

Modern digital cameras rely on the sequential execution of separate image processing steps to produce realistic images. The first two steps are usually related to denoising and demosaicking where the former aims to reduce noise from the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Filippos Kokkinos , Stamatios Lefkimmiatis

With the advent of advances in self-supervised learning, paired clean-noisy data are no longer required in deep learning-based image denoising. However, existing blind denoising methods still require the assumption with regard to noise…

Computer Vision and Pattern Recognition · Computer Science 2021-09-10 Kanggeun Lee , Won-Ki Jeong

The core role of medical images in disease diagnosis makes their quality directly affect the accuracy of clinical judgment. However, due to factors such as low-dose scanning, equipment limitations and imaging artifacts, medical images are…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Tao Tang , Chengxu Yang

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. However, low-count PET scans often suffer from high image noise, which can negatively impact image…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Huidong Xie , Qiong Liu , Bo Zhou , Xiongchao Chen , Xueqi Guo , Chi Liu

Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

In this paper, we present a novel robust framework for low-level vision tasks, including denoising, object removal, frame interpolation, and super-resolution, that does not require any external training data corpus. Our proposed approach…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Gaurav Shrivastava , Ser-Nam Lim , Abhinav Shrivastava

Unsupervised deep image prior (DIP) addresses shortcomings of training data requirements and limited generalization associated with supervised deep learning. The performance of DIP depends on the network architecture and the stopping point…

Deep Learning based methods have emerged as the indisputable leaders for virtually all image restoration tasks. Especially in the domain of microscopy images, various content-aware image restoration (CARE) approaches are now used to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Mangal Prakash , Alexander Krull , Florian Jug

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2022-05-20 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Bias field, which is caused by imperfect MR devices or imaged objects, introduces intensity inhomogeneity into MR images and degrades the performance of MR image analysis methods. Many retrospective algorithms were developed to facilitate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Dong Liang , Xingyu Qiu , Kuanquan Wang , Gongning Luo , Wei Wang , Yashu Liu

Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes. Here we demonstrate that a deep convolutional neural network can be trained to virtually refocus a 2D…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Yichen Wu , Yair Rivenson , Hongda Wang , Yilin Luo , Eyal Ben-David , Laurent A. Bentolila , Christian Pritz , Aydogan Ozcan

Denoising is a fundamental imaging problem. Versatile but fast filtering has been demanded for mobile camera systems. We present an approach to multiscale filtering which allows real-time applications on low-powered devices. The key idea is…

Computer Vision and Pattern Recognition · Computer Science 2018-02-20 Sungjoon Choi , John Isidoro , Pascal Getreuer , Peyman Milanfar

In fluorescence microscopy, spectral unmixing aims to recover individual fluorophore concentrations from spectral images that capture mixed fluorophore emissions. Since classical methods operate pixel-wise and rely on least-squares fitting,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Federico Carrara , Talley Lambert , Mehdi Seifi , Florian Jug

The captured images under low light conditions often suffer insufficient brightness and notorious noise. Hence, low-light image enhancement is a key challenging task in computer vision. A variety of methods have been proposed for this task,…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Cheng Zhang , Qingsen Yan , Yu zhu , Xianjun Li , Jinqiu Sun , Yanning Zhang

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Kun Wang , Lianming Wu , Hongxing Shen , Jianqi Sun