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With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

Fluoroscopy is an imaging technique that uses X-ray to obtain a real-time 2D video of the interior of a 3D object, helping surgeons to observe pathological structures and tissue functions especially during intervention. However, it suffers…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Ruizhou Liu , Qiang Ma , Zhiwei Cheng , Yuanyuan Lyu , Jianji Wang , S. Kevin Zhou

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

Many self-supervised denoising approaches have been proposed in recent years. However, these methods tend to overly smooth images, resulting in the loss of fine structures that are essential for medical applications. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Basar Demir , Yikang Liu , Xiao Chen , Eric Z. Chen , Lin Zhao , Boris Mailhe , Terrence Chen , Shanhui Sun

In this paper, we introduce a novel unsupervised video denoising deep learning approach that can help to mitigate data scarcity issues and shows robustness against different noise patterns, enhancing its broad applicability. Our method…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Mary Damilola Aiyetigbo , Dineshchandar Ravichandran , Reda Chalhoub , Peter Kalivas , Nianyi Li

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Image denoising is of great importance for medical imaging system, since it can improve image quality for disease diagnosis and downstream image analyses. In a variety of applications, dynamic imaging techniques are utilized to capture the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Junshen Xu , Elfar Adalsteinsson

Computed tomography (CT) has played a vital role in medical diagnosis, assessment, and therapy planning, etc. In clinical practice, concerns about the increase of X-ray radiation exposure attract more and more attention. To lower the X-ray…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhicheng Zhang , Xiaokun Liang , Wei Zhao , Lei Xing

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Low-light, long-exposure defocus deblurring remains a challenging problem due to the simultaneous presence of severe blur and complex biased noise. Existing methods typically rely on simplified noise assumptions, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Ziyan Huang , Lang Wu , Hongji Wang , Yifei Liu , Dongliang Tang , Hongqiao Wang

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

The lack of large-scale noisy-clean image pairs restricts supervised denoising methods' deployment in actual applications. While existing unsupervised methods are able to learn image denoising without ground-truth clean images, they either…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Yi Zhang , Dasong Li , Ka Lung Law , Xiaogang Wang , Hongwei Qin , Hongsheng Li

The acquisition conditions for low-dose and high-dose CT images are usually different, so that the shifts in the CT numbers often occur. Accordingly, unsupervised deep learning-based approaches, which learn the target image distribution,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Chanyong Jung , Joonhyung Lee , Sunkyoung You , Jong Chul Ye

Supervised learning-based methods yield robust denoising results, yet they are inherently limited by the need for large-scale clean/noisy paired datasets. The use of unsupervised denoisers, on the other hand, necessitates a more detailed…

Image and Video Processing · Electrical Eng. & Systems 2021-11-30 Nahyun Kim , Donggon Jang , Sunhyeok Lee , Bomi Kim , Dae-Shik Kim

Deep learning approaches in image processing predominantly resort to supervised learning. A majority of methods for image denoising are no exception to this rule and hence demand pairs of noisy and corresponding clean images. Only recently…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Priyatham Kattakinda , A. N. Rajagopalan

Current self-supervised denoising techniques achieve impressive results, yet their real-world application is frequently constrained by substantial computational and memory demands, necessitating a compromise between inference speed and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Tomáš Chobola , Julia A. Schnabel , Tingying Peng

In the last several years deep learning based approaches have come to dominate many areas of computer vision, and image denoising is no exception. Neural networks can learn by example to map noisy images to clean images. However, access to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Jason Lequyer , Reuben Philip , Amit Sharma , Laurence Pelletier

In this paper, we introduce a novel unsupervised network to denoise microscopy videos featured by image sequences captured by a fixed location microscopy camera. Specifically, we propose a DeepTemporal Interpolation method, leveraging a…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Mary Aiyetigbo , Alexander Korte , Ethan Anderson , Reda Chalhoub , Peter Kalivas , Feng Luo , Nianyi Li

Optical neural networks are emerging as powerful machine learning and information processing tools because of their potential advantages in speed and energy efficiency. The training methods of these physical models, however, remain…

Optics · Physics 2026-05-11 Xudong Lv , Yuxiang Sun , Shuo Wang , Nanxing Chen , Jun Guan , Jingtian Hu
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