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Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Laurin Lux , Alexander H. Berger , Alexander Weers , Nico Stucki , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

In this paper, we focus on three problems in deep learning based medical image segmentation. Firstly, U-net, as a popular model for medical image segmentation, is difficult to train when convolutional layers increase even though a deeper…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Wanli Chen , Yue Zhang , Junjun He , Yu Qiao , Yifan Chen , Hongjian Shi , Xiaoying Tang

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

Deep learning techniques are recently being used in fundus image analysis and diabetic retinopathy detection. Microaneurysms are an important indicator of diabetic retinopathy progression. We introduce a two-stage deep learning approach for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-25 Mhd Hasan Sarhan , Shadi Albarqouni , Mehmet Yigitsoy , Nassir Navab , Abouzar Eslami

Glaucoma is a chronic visual disease that may cause permanent irreversible blindness. Measurement of the cup-to-disc ratio (CDR) plays a pivotal role in the detection of glaucoma in its early stage, preventing visual disparities. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Rukhshanda Hussain , Hritam Basak

Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…

We study the impact of different loss functions on lesion segmentation from medical images. Although the Cross-Entropy (CE) loss is the most popular option when dealing with natural images, for biomedical image segmentation the soft Dice…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Adrian Galdran , Gustavo Carneiro , Miguel Ángel González Ballester

Segmentation networks are not explicitly imposed to learn global invariants of an image, such as the shape of an object and the geometry between multiple objects, when they are trained with a standard loss function. On the other hand,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Seher Ozcelik , Sinan Unver , Ilke Ali Gurses , Rustu Turkay , Cigdem Gunduz-Demir

Image segmentation is a fundamental topic in image processing and has been studied for many decades. Deep learning-based supervised segmentation models have achieved state-of-the-art performance but most of them are limited by using…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Xu Chen , Xiangde Luo , Yitian Zhao , Shaoting Zhang , Guotai Wang , Yalin Zheng

This study develops meta-learners for few-shot weakly-supervised segmentation (FWS) to address the challenge of optic disc (OD) and optic cup (OC) segmentation for glaucoma diagnosis with limited labeled fundus images. We significantly…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Pandega Abyan Zumarsyah , Igi Ardiyanto , Hanung Adi Nugroho

We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuto Yokoi , Kazuhiro Hotta

Raster-scan optoacoustic mesoscopy (RSOM) is a powerful, non-invasive optical imaging technique for functional, anatomical, and molecular skin and tissue analysis. However, both the manual and the automated analysis of such images are…

Image and Video Processing · Electrical Eng. & Systems 2020-12-04 Stefan Gerl , Johannes C. Paetzold , Hailong He , Ivan Ezhov , Suprosanna Shit , Florian Kofler , Amirhossein Bayat , Giles Tetteh , Vasilis Ntziachristos , Bjoern Menze

In response to the growing importance of geospatial data, its analysis including semantic segmentation becomes an increasingly popular task in computer vision today. Convolutional neural networks are powerful visual models that yield…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Alexey Bokhovkin , Evgeny Burnaev

Objective: Diabetic macular edema (DME) is the leading cause of severe visual impairment in patients with diabetes. Quantification of retinal fluid, particularly intraretinal fluid (IRF) and subretinal fluid (SRF), plays a critical role in…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zijun Lei , Zikang Xu , Liang Zhang , Ge Song , Hanyu Guo , Dan Cao , Yujia Zhou , Qianjin Feng

Accurate multiclass segmentation of the Circle of Willis (CoW) is essential for neurovascular disease management but remains challenging due to complex vascular topology and variable morphology. Existing deep learning methods often suffer…

Machine Learning · Computer Science 2026-05-01 Jialu Liu , Yue Cui , Shan Yu

Referring Remote Sensing Image Segmentation (RRSIS) is critical for ecological monitoring, urban planning, and disaster management, requiring precise segmentation of objects in remote sensing imagery guided by textual descriptions. This…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Tianxiang Zhang , Zhaokun Wen , Bo Kong , Kecheng Liu , Yisi Zhang , Peixian Zhuang , Jiangyun Li

Objectives: Precise segmentation of total extraocular muscles (EOM) and optic nerve (ON) is essential to assess anatomical development and progression of thyroid-associated ophthalmopathy (TAO). We aim to develop a semantic segmentation…

Optical coherence tomography (OCT) is a powerful and noninvasive method for retinal imaging. In this paper, we introduce a fast segmentation method based on a new variant of spectral graph theory named diffusion maps. The research is…

Computer Vision and Pattern Recognition · Computer Science 2012-10-09 Raheleh Kafieh , Hossein Rabbani , Michael D. Abramoff , Milan Sonka

Face detection has witnessed significant progress due to the advances of deep convolutional neural networks (CNNs). Its central issue in recent years is how to improve the detection performance of tiny faces. To this end, many recent works…

Computer Vision and Pattern Recognition · Computer Science 2019-05-27 Faen Zhang , Xinyu Fan , Guo Ai , Jianfei Song , Yongqiang Qin , Jiahong Wu