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Datasets are rarely a realistic approximation of the target population. Say, prevalence is misrepresented, image quality is above clinical standards, etc. This mismatch is known as sampling bias. Sampling biases are a major hindrance for…

We propose a kernel-based partial permutation test for checking the equality of functional relationship between response and covariates among different groups. The main idea, which is intuitive and easy to implement, is to keep the…

Methodology · Statistics 2021-11-01 Xinran Li , Bo Jiang , Jun S. Liu

Quantile Regression (QR) can be used to estimate aleatoric uncertainty in deep neural networks and can generate prediction intervals. Quantifying uncertainty is particularly important in critical applications such as clinical diagnosis,…

Machine Learning · Computer Science 2023-09-15 Haleh Akrami , Omar Zamzam , Anand Joshi , Sergul Aydore , Richard Leahy

We propose a flexible Bayesian approach for estimating the joint density of a multivariate outcome of interest in the presence of categorical covariates. Leveraging a Gaussian copula framework, our method effectively captures the dependence…

Methodology · Statistics 2026-04-10 Giovanni Toto , Peter Müller , Abhra Sarkar

Quantum scattering calculations for all but low-dimensional systems at low energies must rely on approximations. All approximations introduce errors. The impact of these errors is often difficult to assess because they depend on the…

Consider a setting with multiple units (e.g., individuals, cohorts, geographic locations) and outcomes (e.g., treatments, times, items), where the goal is to learn a multivariate distribution for each unit-outcome entry, such as the…

Machine Learning · Statistics 2025-10-21 Kyuseong Choi , Jacob Feitelberg , Caleb Chin , Anish Agarwal , Raaz Dwivedi

The large-scale multiple testing inherent to high throughput biological data necessitates very high statistical stringency and thus true effects in data are difficult to detect unless they have high effect sizes. One promising approach for…

Methodology · Statistics 2022-03-14 Mohamad Hasan , Paul Schliekelman

We introduce the SoftBart approach from Bayesian ensemble learning to estimate the relationship between multipollutant mixtures and health on chronic exposures in epidemiology research. This approach offers several key advantages over…

Quantitative Methods · Quantitative Biology 2025-05-26 Yu-Chien Ning , Xin Zhou , Francine Laden , Molin Wang

System outputs such as eigenfrequencies or strain data, often used in structural health monitoring (SHM), not only react to damage but also depend on environmental conditions. When trying to correct for these confounding effects, it is…

Applications · Statistics 2026-03-25 Lizzie Neumann , Philipp Wittenberg , Jan Gertheiss

Deep learning has the potential to dramatically impact navigation and tracking state estimation problems critical to autonomous vehicles and robotics. Measurement uncertainties in state estimation systems based on Kalman and other Bayes…

Machine Learning · Computer Science 2021-06-16 Rebecca L. Russell , Christopher Reale

Covariate adjustment is widely recommended to improve statistical efficiency in randomized clinical trials (RCTs), yet empirical evidence comparing available strategies remains limited. This lack of real-world evaluation leaves unresolved…

Applications · Statistics 2026-02-03 Yulin Shao , Liangbo Lyu , Menggang Yu , Bingkai Wang

Compared to mean regression and quantile regression, the literature on modal regression is very sparse. A unifying framework for Bayesian modal regression is proposed, based on a family of unimodal distributions indexed by the mode, along…

Methodology · Statistics 2024-07-02 Qingyang Liu , Xianzheng Huang , Rai Bai

The performance of deep learning (DL) methods for the analysis of cine cardiovascular magnetic resonance (CMR) is typically assessed in terms of accuracy, overlooking precision. In this work, uncertainty estimation techniques, namely deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Dewmini Hasara Wickremasinghe , Michelle Gibogwe , Andrew Bell , Esther Puyol-Antón , Muhummad Sohaib Nazir , Reza Razavi , Bruno Paun , Paul Aljabar , Andrew P. King

Mendelian randomization (MR) is a statistical method exploiting genetic variants as instrumental variables to estimate the causal effect of modifiable risk factors on an outcome of interest. Despite wide uses of various popular two-sample…

Methodology · Statistics 2021-11-17 Anqi Wang , Zhonghua Liu

In behavioral and psychiatric research, data consisting of a per-subject proportion of "successes" and "failures" over a finite number of trials often arise. This kind of clustered binary data are usually non-normally distributed, which can…

Quantitative Methods · Quantitative Biology 2016-05-09 Alberto Ferrari , Mario Comelli

We describe how to calculate standard errors for A/B tests that include clustered data, ratio metrics, and/or covariate adjustment. We may do this for power analysis/sample size calculations prior to running an experiment using historical…

Methodology · Statistics 2024-06-12 Tim Hesterberg , Ben Knight

This paper addresses the scalability problem of Bayesian deep neural networks. The performance of deep neural networks is undermined by the fact that these algorithms have poorly calibrated measures of uncertainty. This restricts their…

Machine Learning · Computer Science 2021-04-20 Sam Maksoud , Kun Zhao , Can Peng , Brian C. Lovell

This paper studies the high-dimensional mixed linear regression (MLR) where the output variable comes from one of the two linear regression models with an unknown mixing proportion and an unknown covariance structure of the random…

Methodology · Statistics 2020-11-10 Linjun Zhang , Rong Ma , T. Tony Cai , Hongzhe Li

Model misspecification in multivariate econometric models can strongly influence estimates of quantities of interest such as structural parameters, forecast distributions or responses to structural shocks, even more so if higher-order…

Econometrics · Economics 2025-09-09 Florian Huber , Massimiliano Marcellino , Tobias Scheckel

A Hilbert space embedding of a distribution---in short, a kernel mean embedding---has recently emerged as a powerful tool for machine learning and inference. The basic idea behind this framework is to map distributions into a reproducing…

Machine Learning · Statistics 2020-12-15 Krikamol Muandet , Kenji Fukumizu , Bharath Sriperumbudur , Bernhard Schölkopf
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