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Magnetic Resonance Imaging (MRI) is a critical tool in modern medical diagnostics, yet its prolonged acquisition time remains a critical limitation, especially in time-sensitive clinical scenarios. While undersampling strategies can…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Mohammed Alsubaie , Wenxi Liu , Linxia Gu , Ovidiu C. Andronesi , Sirani M. Perera , Xianqi Li

Traditional reconstruction-based methods have struggled to achieve competitive performance in anomaly detection. In this paper, we introduce Denoising Diffusion Anomaly Detection (DDAD), a novel denoising process for image reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Arian Mousakhan , Thomas Brox , Jawad Tayyub

Reconstruction-based anomaly detection via denoising diffusion model has limitations in determining appropriate noise parameters that can degrade anomalies while preserving normal characteristics. Also, normal regions can fluctuate…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Eunwoo Kim , Un Yang , Cheol Lae Roh , Stefano Ermon

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz

Machine learning-based medical anomaly detection is an important problem that has been extensively studied. Numerous approaches have been proposed across various medical application domains and we observe several similarities across these…

Machine Learning · Computer Science 2021-04-14 Tharindu Fernando , Harshala Gammulle , Simon Denman , Sridha Sridharan , Clinton Fookes

Currently, applying diffusion models in pixel space of high resolution images is difficult. Instead, existing approaches focus on diffusion in lower dimensional spaces (latent diffusion), or have multiple super-resolution levels of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Emiel Hoogeboom , Jonathan Heek , Tim Salimans

In medical imaging, segmentation models have known a significant improvement in the past decade and are now used daily in clinical practice. However, similar to classification models, segmentation models are affected by adversarial attacks.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Nikos Paragios , Marie-Pierre Revel , Maria Vakalopoulou

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Denosing diffusion model, as a generative model, has received a lot of attention in the field of image generation recently, thanks to its powerful generation capability. However, diffusion models have not yet received sufficient research in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 ZiHan Cao , ShiQi Cao , Xiao Wu , JunMing Hou , Ran Ran , Liang-Jian Deng

Denoising diffusion models have found applications in image segmentation by generating segmented masks conditioned on images. Existing studies predominantly focus on adjusting model architecture or improving inference, such as test-time…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Yunguan Fu , Yiwen Li , Shaheer U Saeed , Matthew J Clarkson , Yipeng Hu

Ultrasound imaging, despite its widespread use in medicine, often suffers from various sources of noise and artifacts that impact the signal-to-noise ratio and overall image quality. Enhancing ultrasound images requires a delicate balance…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

In supervised learning for image denoising, usually the paired clean images and noisy images are collected or synthesised to train a denoising model. L2 norm loss or other distance functions are used as the objective function for training.…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Yutong Xie , Minne Yuan , Bin Dong , Quanzheng Li

Denoising diffusion models have emerged as a dominant approach for image generation, however they still suffer from slow convergence in training and color shift issues in sampling. In this paper, we identify that these obstacles can be…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Hu Yu , Li Shen , Jie Huang , Hongsheng Li , Feng Zhao

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Medical image segmentation is a challenging task, made more difficult by many datasets' limited size and annotations. Denoising diffusion probabilistic models (DDPM) have recently shown promise in modelling the distribution of natural…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Margherita Rosnati , Melanie Roschewitz , Ben Glocker

Unsupervised Anomaly Detection has become a popular method to detect pathologies in medical images as it does not require supervision or labels for training. Most commonly, the anomaly detection model generates a "normal" version of an…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Johannes Paetzold , Georgios Kaissis , Daniel Rueckert

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Hao Guan , Mingxia Liu

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang