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Nosie is an important cause of low quality Optical coherence tomography (OCT) image. The neural network model based on Convolutional neural networks(CNNs) has demonstrated its excellent performance in image denoising. However, OCT image…

Image and Video Processing · Electrical Eng. & Systems 2022-05-03 Jie Du , Xujian Yang , Kecheng Jin , Xuanzheng Qi , Hu Chen

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

In PET, the amount of relative (signal-dependent) noise present in different body regions can be significantly different and is inherently related to the number of counts present in that region. The number of counts in a region depends, in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ye Li , Jianan Cui , Junyu Chen , Guodong Zeng , Scott Wollenweber , Floris Jansen , Se-In Jang , Kyungsang Kim , Kuang Gong , Quanzheng Li

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and…

Medical Physics · Physics 2017-12-12 Hu Chen , Yi Zhang , Mannudeep K. Kalra , Feng Lin , Yang Chen , Peixi Liao , Jiliu Zhou , Ge Wang

Positron emission tomography (PET) reconstruction has become an ill-posed inverse problem due to low-count projection data, and a robust algorithm is urgently required to improve imaging quality. Recently, the deep image prior (DIP) has…

Image and Video Processing · Electrical Eng. & Systems 2021-11-01 Chenyu Shen , Wenjun Xia , Hongwei Ye , Mingzheng Hou , Hu Chen , Yan Liu , Jiliu Zhou , Yi Zhang

This paper evaluates the performance of supervised and unsupervised deep learning models for denoising positron emission tomography (PET) images in the presence of reduced acquisition times. Our experiments consider 212 studies (56908…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Ivan Kruzhilov , Stepan Kudin , Luka Vetoshkin , Elena Sokolova , Vladimir Kokh

In "extreme" computational imaging that collects extremely undersampled or noisy measurements, obtaining an accurate image within a reasonable computing time is challenging. Incorporating image mapping convolutional neural networks (CNN)…

Machine Learning · Statistics 2023-08-31 Il Yong Chun , Jeffrey A. Fessler

Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past…

Computer Vision and Pattern Recognition · Computer Science 2018-08-13 Chenyu You , Qingsong Yang , Hongming Shan , Lars Gjesteby , Guang Li , Shenghong Ju , Zhuiyang Zhang , Zhen Zhao , Yi Zhang , Wenxiang Cong , Ge Wang

Low-dose computed tomography (LDCT) is the standard modality for lung cancer screening, known for its low radiation dose but high noise levels. While existing literature focuses on denoising LDCT images, comparative research on simulating…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaying Liu , Anna Corti , Valentina D. A. Corino , Luca Mainardi

Deep convolutional neural networks (DCNN) have demonstrated its capability to convert MR image to pseudo CT for PET attenuation correction in PET/MRI. Conventionally, attenuated events are corrected in sinogram space using attenuation maps…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Jaewon Yang , Dookun Park , Jae Ho Sohn , Zhen Jane Wang , Grant T. Gullberg , Youngho Seo

To reduce the potential radiation risk, low-dose CT has attracted much attention. However, simply lowering the radiation dose will lead to significant deterioration of the image quality. In this paper, we propose a noise reduction method…

Medical Physics · Physics 2016-10-04 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…

Computer Vision and Pattern Recognition · Computer Science 2014-07-14 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

The explosive rise of the use of Computer tomography (CT) imaging in medical practice has heightened public concern over the patient's associated radiation dose. However, reducing the radiation dose leads to increased noise and artifacts,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Sutanu Bera , Prabir Kumar Biswas

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

In this work, a denoising Cycle-GAN (Cycle Consistent Generative Adversarial Network) is implemented to yield high-field, high resolution, high signal-to-noise ratio (SNR) Magnetic Resonance Imaging (MRI) images from simulated low-field,…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Fernando Vega , Abdoljalil Addeh , M. Ethan MacDonald

This work tackles the issue of noise removal from images, focusing on the well-known DCT image denoising algorithm. The latter, stemming from signal processing, has been well studied over the years. Though very simple, it is still used in…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Sébastien Herbreteau , Charles Kervrann