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Identifying variables responsible for changes to a biological system enables applications in drug target discovery and cell engineering. Given a pair of observational and interventional datasets, the goal is to isolate the subset of…

Machine Learning · Computer Science 2025-06-02 Menghua Wu , Umesh Padia , Sean H. Murphy , Regina Barzilay , Tommi Jaakkola

This work introduces a novel principle for disentanglement we call mechanism sparsity regularization, which applies when the latent factors of interest depend sparsely on observed auxiliary variables and/or past latent factors. We propose a…

Causal disentanglement from soft interventions is identifiable under the assumptions of linear interventional faithfulness and availability of both observational and interventional data. Previous research has looked into this problem from…

Machine Learning · Computer Science 2025-09-03 Jifan Zhang , Michelle M. Li , Elena Zheleva

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

Learning disentanglement aims at finding a low dimensional representation which consists of multiple explanatory and generative factors of the observational data. The framework of variational autoencoder (VAE) is commonly used to…

Machine Learning · Computer Science 2023-12-20 Mengyue Yang , Furui Liu , Zhitang Chen , Xinwei Shen , Jianye Hao , Jun Wang

In some causal inference scenarios, the treatment variable is measured inaccurately, for instance in epidemiology or econometrics. Failure to correct for the effect of this measurement error can lead to biased causal effect estimates.…

Machine Learning · Computer Science 2024-09-13 Antti Pöllänen , Pekka Marttinen

We propose a novel approach to disentangle the generative factors of variation underlying a given set of observations. Our method builds upon the idea that the (unknown) low-dimensional manifold underlying the data space can be explicitly…

Machine Learning · Computer Science 2021-10-05 Marco Fumero , Luca Cosmo , Simone Melzi , Emanuele Rodolà

Causal representation learning algorithms discover lower-dimensional representations of data that admit a decipherable interpretation of cause and effect; as achieving such interpretable representations is challenging, many causal learning…

Machine Learning · Computer Science 2023-11-09 Elise Walker , Jonas A. Actor , Carianne Martinez , Nathaniel Trask

We introduce a conditional generative model for learning to disentangle the hidden factors of variation within a set of labeled observations, and separate them into complementary codes. One code summarizes the specified factors of variation…

Machine Learning · Computer Science 2016-11-11 Michael Mathieu , Junbo Zhao , Pablo Sprechmann , Aditya Ramesh , Yann LeCun

The ability to conduct interventions plays a pivotal role in learning causal relationships among variables, thus facilitating applications across diverse scientific disciplines such as genomics, economics, and machine learning. However, in…

Machine Learning · Statistics 2024-11-04 Abhinav Kumar , Kirankumar Shiragur , Caroline Uhler

We study the identification of causal effects, motivated by two improvements to identifiability which can be attained if one knows that some variables in a causal graph are functionally determined by their parents (without needing to know…

Artificial Intelligence · Computer Science 2024-05-24 Yizuo Chen , Adnan Darwiche

In causal models, a given mechanism is assumed to be invariant to changes of other mechanisms. While this principle has been utilized for inference in settings where the causal variables are observed, theoretical insights when the variables…

Machine Learning · Statistics 2023-12-07 Simon Bing , Jonas Wahl , Urmi Ninad , Jakob Runge

Learning high-level causal representations together with a causal model from unstructured low-level data such as pixels is impossible from observational data alone. We prove under mild assumptions that this representation is however…

Machine Learning · Statistics 2022-10-12 Johann Brehmer , Pim de Haan , Phillip Lippe , Taco Cohen

Many real-world decision-making tasks require learning causal relationships between a set of variables. Traditional causal discovery methods, however, require that all variables are observed, which is often not feasible in practical…

Methodology · Statistics 2023-06-27 Raj Agrawal , Chandler Squires , Neha Prasad , Caroline Uhler

Foundation models for structured time series data must contend with a fundamental challenge: observations often conflate the true underlying physical phenomena with systematic distortions introduced by measurement instruments. This…

Machine Learning · Computer Science 2025-07-09 Jeroen Audenaert , Daniel Muthukrishna , Paul F. Gregory , David W. Hogg , V. Ashley Villar

We present a unified framework for studying the identifiability of representations learned from simultaneously observed views, such as different data modalities. We allow a partially observed setting in which each view constitutes a…

We consider the linear causal representation learning setting where we observe a linear mixing of $d$ unknown latent factors, which follow a linear structural causal model. Recent work has shown that it is possible to recover the latent…

Machine Learning · Computer Science 2024-11-05 Tianyu Chen , Kevin Bello , Francesco Locatello , Bryon Aragam , Pradeep Ravikumar

We study causal discovery from observational data in linear Gaussian systems affected by \emph{mixed latent confounding}, where some unobserved factors act broadly across many variables while others influence only small subsets. This…

Machine Learning · Computer Science 2026-01-01 Amir Asiaee , Samhita Pal , James O'quinn , James P. Long

Causal inference methods based on conditional independence construct Markov equivalent graphs, and cannot be applied to bivariate cases. The approaches based on independence of cause and mechanism state, on the contrary, that causal…

Machine Learning · Computer Science 2021-08-04 Nataliya Sokolovska , Pierre-Henri Wuillemin

Causal discovery aims to infer causal relationships among variables from observational data, typically represented by a directed acyclic graph (DAG). Most existing methods assume independent and identically distributed observations, an…

Methodology · Statistics 2026-03-27 Alex Chen , Qing Zhou