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Unstructured text in medical notes and dialogues contains rich information. Recent advancements in Large Language Models (LLMs) have demonstrated superior performance in question answering and summarization tasks on unstructured text data,…

Computation and Language · Computer Science 2024-05-31 Yuhao Chen , Zhimu Wang , Bo Wen , Farhana Zulkernine

This study explores the application of Large Language Models (LLMs), specifically GPT-4, in the analysis of classroom dialogue, a crucial research task for both teaching diagnosis and quality improvement. Recognizing the knowledge-intensive…

Computation and Language · Computer Science 2024-10-08 Yun Long , Haifeng Luo , Yu Zhang

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

As Large Language Models (LLMs) are predictive models building their response based on the words in the prompts, there is a risk that small talk and irrelevant information may alter the response and the suggestion given. Therefore, this…

Computation and Language · Computer Science 2023-09-19 Myriam Safrai , Amos Azaria

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Matching patients to clinical trial options is critical for identifying novel treatments, especially in oncology. However, manual matching is labor-intensive and error-prone, leading to recruitment delays. Pipelines incorporating large…

Computation and Language · Computer Science 2025-09-25 Braxton A. Morrison , Madhumita Sushil , Jacob S. Young

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Multimodal large language models (MLLMs) hold considerable promise for applications in healthcare. However, their deployment in safety-critical settings is hindered by two key limitations: (i) sensitivity to prompt design, and (ii) a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Anita Kriz , Elizabeth Laura Janes , Xing Shen , Tal Arbel

Reinforcement learning (RL)-based dynamic treatment regimes (DTRs) hold promise for automating complex clinical decision-making, yet their practical deployment remains hindered by the intensive engineering required to inject clinical…

Machine Learning · Computer Science 2025-08-08 Zhiyao Luo , Tingting Zhu

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

Large Language Models, such as Generative Pre-trained Transformer 3 (aka. GPT-3), have been developed to understand language through the analysis of extensive text data, allowing them to identify patterns and connections between words.…

Computation and Language · Computer Science 2023-10-03 Baphumelele Masikisiki , Vukosi Marivate , Yvette Hlope

This study is a pioneering endeavor to investigate the capabilities of Large Language Models (LLMs) in addressing conceptual questions within the domain of mechanical engineering with a focus on mechanics. Our examination involves a…

Computation and Language · Computer Science 2024-01-25 Jie Tian , Jixin Hou , Zihao Wu , Peng Shu , Zhengliang Liu , Yujie Xiang , Beikang Gu , Nicholas Filla , Yiwei Li , Ning Liu , Xianyan Chen , Keke Tang , Tianming Liu , Xianqiao Wang

Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…

Computation and Language · Computer Science 2024-04-11 Michael Wornow , Alejandro Lozano , Dev Dash , Jenelle Jindal , Kenneth W. Mahaffey , Nigam H. Shah

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

Instruction-tuned Large Language Models (LLMs) have exhibited impressive language understanding and the capacity to generate responses that follow specific prompts. However, due to the computational demands associated with training these…

Computation and Language · Computer Science 2024-03-26 Yida Mu , Ben P. Wu , William Thorne , Ambrose Robinson , Nikolaos Aletras , Carolina Scarton , Kalina Bontcheva , Xingyi Song

The precipitous rise and adoption of Large Language Models (LLMs) have shattered expectations with the fastest adoption rate of any consumer-facing technology in history. Healthcare, a field that traditionally uses NLP techniques, was bound…

Computation and Language · Computer Science 2023-10-10 Surjya Ray , Pratik Mehta , Hongen Zhang , Ada Chaman , Jian Wang , Chung-Jen Ho , Michael Chiou , Tashfeen Suleman

This case study investigates the task of job classification in a real-world setting, where the goal is to determine whether an English-language job posting is appropriate for a graduate or entry-level position. We explore multiple…

Computation and Language · Computer Science 2023-04-19 Benjamin Clavié , Alexandru Ciceu , Frederick Naylor , Guillaume Soulié , Thomas Brightwell

The emergence of Small Language Models (SLMs) as privacy-preserving alternatives for sensitive applications raises a fundamental question about their inherent understanding capabilities compared to Large Language Models (LLMs). This paper…

Computation and Language · Computer Science 2025-07-15 Hong Jia , Shiya Fu , Feng Xia , Vassilis Kostakos , Ting Dang

Large Language Models (LLMs) have shown promise in various domains, including healthcare, with significant potential to transform mental health applications by enabling scalable and accessible solutions. This study aims to provide a…

Artificial Intelligence · Computer Science 2025-11-25 Abdelrahman Hanafi , Mohammed Saad , Noureldin Zahran , Radwa J. Hanafy , Mohammed E. Fouda
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