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Modern Mixed Integer Linear Programming (MILP) solvers use the Branch-and-Bound algorithm together with a plethora of auxiliary components that speed up the search. In recent years, there has been an explosive development in the use of…

Optimization and Control · Mathematics 2024-11-28 Lara Scavuzzo , Karen Aardal , Neil Yorke-Smith

An important problem in optimization is the construction of mixed-integer programming (MIP) formulations of disjunctive constraints that are both strong and small. Motivated by lower bounds on the number of integer variables that are…

Optimization and Control · Mathematics 2017-12-05 Joey Huchette , Juan Pablo Vielma

Recent growing complexity in space missions has led to an active research field of space logistics and mission design. This research field leverages the key ideas and methods used to handle complex terrestrial logistics to tackle space…

Optimization and Control · Mathematics 2025-08-27 Koki Ho , Yuri Shimane , Masafumi Isaji

A novel two-phase molecule inference framework, mol-infer, has recently been developed to infer chemical graphs with prescribed abstract structures and desired property values through mixed integer linear programming (MILP) under the…

Quantitative Methods · Quantitative Biology 2026-05-29 Jianshen Zhu , Raveena Rai , Taiyo Sohkawa , Naveed Ahmed Azam , Kazuya Haraguchi , Liang Zhao , Tatsuya Akutsu

We propose a supervised learning framework for computing solutions of multi-parametric Mixed Integer Linear Programs (MILPs) that arise in Model Predictive Control. Our approach also quantifies sub-optimality for the computed solutions.…

Systems and Control · Electrical Eng. & Systems 2023-03-24 Luigi Russo , Siddharth H. Nair , Luigi Glielmo , Francesco Borrelli

Discrete black-box optimization problems are challenging for model-based optimization (MBO) algorithms, such as Bayesian optimization, due to the size of the search space and the need to satisfy combinatorial constraints. In particular,…

Optimization and Control · Mathematics 2022-06-15 Theodore Papalexopoulos , Christian Tjandraatmadja , Ross Anderson , Juan Pablo Vielma , David Belanger

We propose an extended variant of the reformulation and decomposition algorithm for solving a special class of mixed-integer bilevel linear programs (MIBLPs) where continuous and integer variables are involved in both upper- and lower-level…

Optimization and Control · Mathematics 2018-07-03 Dajun Yue , Jiyao Gao , Bo Zeng , Fengqi You

Clustering is a popular unsupervised learning tool often used to discover groups within a larger population such as customer segments, or patient subtypes. However, despite its use as a tool for subgroup discovery and description - few…

Machine Learning · Computer Science 2021-12-13 Connor Lawless , Jayant Kalagnanam , Lam M. Nguyen , Dzung Phan , Chandra Reddy

We study a two-stage mixed-integer linear program (MILP) with more than 1 million binary variables in the second stage. We develop a two-level approach by constructing a semi-coarse model (coarsened with respect to variables) and a coarse…

Optimization and Control · Mathematics 2015-04-20 Fu Lin , Sven Leyffer , Todd Munson

Partial label learning (PLL) is a typical weakly supervised learning problem, where each training example is associated with a set of candidate labels among which only one is true. Most existing PLL approaches assume that the incorrect…

Machine Learning · Computer Science 2023-02-02 Congyu Qiao , Ning Xu , Xin Geng

Integer linear programming (ILP) encompasses a very important class of optimization problems that are of great interest to both academia and industry. Several algorithms are available that attempt to explore the solution space of this class…

Emerging Technologies · Computer Science 2018-08-31 Fabio L. Traversa , Massimiliano Di Ventra

Machine Learning Interatomic Potentials (MLIPs) are becoming a central tool in simulation-based chemistry. However, like most deep learning models, MLIPs struggle to make accurate predictions on out-of-distribution data or when trained in a…

Machine Learning · Computer Science 2026-01-19 Dario Coscia , Pim de Haan , Max Welling

There has been growing interest in implementing massive MIMO systems by one-bit analog-to-digital converters (ADCs), which have the benefit of reducing the power consumption and hardware complexity. One-bit MIMO detection arises in such a…

Information Theory · Computer Science 2023-07-04 Cheng-Yang Yu , Mingjie Shao , Wei-Kun Chen , Ya-Feng Liu , Wing-Kin Ma

Cutting planes for mixed-integer linear programs (MILPs) are typically computed in rounds by iteratively solving optimization problems, the so-called separation. Instead, we reframe the problem of finding good cutting planes as a continuous…

Optimization and Control · Mathematics 2023-07-10 Didier Chételat , Andrea Lodi

Biclustering techniques have been widely used to identify homogeneous subgroups within large data matrices, such as subsets of genes similarly expressed across subsets of patients. Mining a max-sum sub-matrix is a related but distinct…

Machine Learning · Statistics 2017-09-26 Vincent Branders , Pierre Schaus , Pierre Dupont

In this study, we introduce an innovative deep learning framework that employs a transformer model to address the challenges of mixed-integer programs, specifically focusing on the Capacitated Lot Sizing Problem (CLSP). Our approach, to our…

Artificial Intelligence · Computer Science 2024-05-27 Joshua F. Cooper , Seung Jin Choi , I. Esra Buyuktahtakin

Many real-world problems can be efficiently modeled as Mixed Integer Linear Programs (MILPs) and solved with the Branch-and-Bound method. Prior work has shown the existence of MILP backdoors, small sets of variables such that prioritizing…

Artificial Intelligence · Computer Science 2024-08-02 Junyang Cai , Taoan Huang , Bistra Dilkina

We solve large-scale mixed-integer linear programs (MILPs) via distributed asynchronous saddle point computation. This is motivated by the MILPs being able to model problems in multi-agent autonomy, e.g., task assignment problems and…

Optimization and Control · Mathematics 2022-11-23 Luke Fina , Matthew Hale

We present new models of optimization-based task and motion planning (TAMP) for robotic pick-and-place (P&P), which plan action sequences and motion trajectory with low computational costs. We improved an existing state-of-the-art TAMP…

Robotics · Computer Science 2022-01-24 Takuma Kogo , Kei Takaya , Hiroyuki Oyama

Integer programming (IP) is central to many combinatorial optimization tasks but remains challenging due to its NP-hard nature. A practical way to improve IP solvers is to manually design acceleration cuts, i.e., inequalities that speed up…

Artificial Intelligence · Computer Science 2026-02-16 Milad Yazdani , Mahdi Mostajabdaveh , Samin Aref , Zirui Zhou