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Imaging modalities such as Computed Tomography (CT) and Positron Emission Tomography (PET) are key in cancer detection, inspiring Deep Neural Networks (DNN) models that merge these scans for tumor segmentation. When both CT and PET scans…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Nada Saadi , Numan Saeed , Mohammad Yaqub , Karthik Nandakumar

Dynamic positron emission tomography (dPET) is currently a widely used medical imaging technique for the clinical diagnosis, staging and therapy guidance of all kinds of human cancers. Higher temporal imaging resolution for the early stage…

Medical Physics · Physics 2021-12-07 Zixiang Chen , Yaping Wu , Na Zhang , Yu Shen , Hairong Zheng , Dong Liang , Meiyun Wang , Zhanli Hu

Modern-day surveillance systems perform person recognition using deep learning-based face verification networks. Most state-of-the-art facial verification systems are trained using visible spectrum images. But, acquiring images in the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Nithin Gopalakrishnan Nair , Vishal M. Patel

Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Numan Saeed , Shahad Hardan , Muhammad Ridzuan , Nada Saadi , Karthik Nandakumar , Mohammad Yaqub

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Computed tomography (CT) imaging could be very practical for diagnosing various diseases. However, the nature of the CT images is even more diverse since the resolution and number of the slices of a CT scan are determined by the machine and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-11 Chih-Chung Hsu , Chi-Han Tsai , Guan-Lin Chen , Sin-Di Ma , Shen-Chieh Tai

In this work, we address the challenge of multi-task image generation with limited data for denoising diffusion probabilistic models (DDPM), a class of generative models that produce high-quality images by reversing a noisy diffusion…

Machine Learning · Computer Science 2023-11-29 Delaram Pirhayatifard , Mohammad Taha Toghani , Guha Balakrishnan , César A. Uribe

Positron Emission Tomography (PET) imaging is a vital tool in medical diagnostics, offering detailed insights into molecular processes within the human body. However, PET images often suffer from complicated noise, which can obscure…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Xuehua Ye , Hongxu Yang , Adam J. Schwarz

In this work, we introduce a new deep learning approach based on diffusion posterior sampling (DPS) to perform material decomposition from spectral CT measurements. This approach combines sophisticated prior knowledge from unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Xiao Jiang , Grace J. Gang , J. Webster Stayman

Biomedical image segmentation is crucial for accurately diagnosing and analyzing various diseases. However, Convolutional Neural Networks (CNNs) and Transformers, the most commonly used architectures for this task, struggle to effectively…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Rong Zhou , Zhengqing Yuan , Zhiling Yan , Weixiang Sun , Kai Zhang , Yiwei Li , Yanfang Ye , Xiang Li , Lifang He , Lichao Sun

Diffusion-based models have achieved state-of-the-art performance on text-to-image synthesis tasks. However, one critical limitation of these models is the low fidelity of generated images with respect to the text description, such as…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Qiucheng Wu , Yujian Liu , Handong Zhao , Trung Bui , Zhe Lin , Yang Zhang , Shiyu Chang

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

Deep neural networks (DNNs) offer significant promise for improving breast cancer diagnosis in medical imaging. However, these models are highly susceptible to adversarial attacks--small, imperceptible changes that can mislead…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Yasamin Medghalchi , Moein Heidari , Clayton Allard , Leonid Sigal , Ilker Hacihaliloglu

The advancement of medical image segmentation techniques has been propelled by the adoption of deep learning techniques, particularly UNet-based approaches, which exploit semantic information to improve the accuracy of segmentations.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Ranmin Wang , Limin Zhuang , Hongkun Chen , Boyan Xu , Ruichu Cai

Diffusion models are the current state of the art for generating photorealistic images. Controlling the sampling process for constrained image generation tasks such as inpainting, however, remains challenging since exact conditioning on…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Anji Liu , Mathias Niepert , Guy Van den Broeck

Radiation exposure in positron emission tomography (PET) imaging limits its usage in the studies of radiation-sensitive populations, e.g., pregnant women, children, and adults that require longitudinal imaging. Reducing the PET radiotracer…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Viswanath P. Sudarshan , Uddeshya Upadhyay , Gary F. Egan , Zhaolin Chen , Suyash P. Awate

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering