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Mental disorders are clinically significant patterns of behavior that are associated with stress and/or impairment in social, occupational, or family activities. People suffering from such disorders are often misjudged and poorly diagnosed…

Machine Learning · Computer Science 2025-09-03 Abu Shad Ahammed , Sayeri Mukherjee , Roman Obermaisser

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

The 2022 World Mental Health Report calls for global mental health care reform, amid rising prevalence of issues like anxiety and depression that affect nearly one billion people worldwide. Traditional in-person therapy fails to meet this…

Computers and Society · Computer Science 2025-10-21 Xun Wei , Pukai Zhou , Zeyu Wang

Most of the existing Large Language Model (LLM) benchmarks on scientific problem reasoning focus on problems grounded in high-school subjects and are confined to elementary algebraic operations. To systematically examine the reasoning…

Computation and Language · Computer Science 2024-07-01 Xiaoxuan Wang , Ziniu Hu , Pan Lu , Yanqiao Zhu , Jieyu Zhang , Satyen Subramaniam , Arjun R. Loomba , Shichang Zhang , Yizhou Sun , Wei Wang

Psychological consultation is essential for improving mental health and well-being, yet challenges such as the shortage of qualified professionals and scalability issues limit its accessibility. To address these challenges, we explore the…

Computation and Language · Computer Science 2024-08-30 Rafael Souza , Jia-Hao Lim , Alexander Davis

Large language models (LLMs) excel at solving problems with clear and complete statements, but often struggle with nuanced environments or interactive tasks which are common in most real-world scenarios. This highlights the critical need…

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

Large language models (LLMs) demonstrate remarkable breadth of knowledge, yet their ability to reason about computational processes remains poorly understood. Closing this gap matters for practitioners who rely on LLMs to guide algorithm…

Computation and Language · Computer Science 2026-04-07 Sohan Venkatesh , Ashish Mahendran Kurapath , Tejas Melkote

This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance…

Computation and Language · Computer Science 2025-01-20 Nada Saadi , Tathagata Raha , Clément Christophe , Marco AF Pimentel , Ronnie Rajan , Praveen K Kanithi

For Large Language Models (LLMs) to be reliably deployed in both everyday and high-stakes domains, knowing when not to answer is equally critical as answering correctly. Real-world user queries, which can be underspecified, ill-posed, or…

Artificial Intelligence · Computer Science 2025-06-11 Polina Kirichenko , Mark Ibrahim , Kamalika Chaudhuri , Samuel J. Bell

Large Language Models (LLMs) with hundreds of billions of parameters have exhibited human-like intelligence by learning from vast amounts of internet-scale data. However, the uninterpretability of large-scale neural networks raises concerns…

Computation and Language · Computer Science 2025-09-23 Wei Xie , Shuoyoucheng Ma , Zhenhua Wang , Enze Wang , Kai Chen , Xiaobing Sun , Baosheng Wang

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

The emergence of Large Language Models (LLMs) has fundamentally transformed natural language processing, making them indispensable across domains ranging from conversational systems to scientific exploration. However, their pre-trained…

Brain localization, which describes the association between specific regions of the brain and their corresponding functions, is widely accepted in the field of cognitive science as an objective fact. Today's large language models (LLMs)…

Computation and Language · Computer Science 2023-10-24 Jun Zhao , Zhihao Zhang , Yide Ma , Qi Zhang , Tao Gui , Luhui Gao , Xuanjing Huang

Large language models (LLMs) are increasingly being adopted in high-stakes domains. Their potential to encode evolving social contexts and to generate plausible scenarios position them as promising tools in social policymaking. This article…

Artificial Intelligence · Computer Science 2026-01-30 Pierre Le Coz , Jia An Liu , Debarun Bhattacharjya , Georgina Curto , Serge Stinckwich

Mental health disorders affect hundreds of millions globally, and the Web now serves as a primary medium for accessing support, information, and assessment. Large language models (LLMs) offer scalable and accessible assistance, yet their…