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The most prevalent form of bladder cancer is urothelial carcinoma, characterized by a high recurrence rate and substantial lifetime treatment costs for patients. Grading is a prime factor for patient risk stratification, although it suffers…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Saul Fuster , Umay Kiraz , Trygve Eftestøl , Emiel A. M. Janssen , Kjersti Engan

Recent advances in medical imaging techniques have led to significant improvements in the management of prostate cancer (PCa). In particular, multi-parametric MRI (mp-MRI) continues to gain clinical acceptance as the preferred imaging…

Image and Video Processing · Electrical Eng. & Systems 2019-10-08 Ruiming Cao , Xinran Zhong , Fabien Scalzo , Steven Raman , Kyung hyun Sung

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Cancer is one of the most dangerous diseases to humans, and yet no permanent cure has been developed for it. Breast cancer is one of the most common cancer types. According to the National Breast Cancer foundation, in 2020 alone, more than…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ali Bou Nassif , Manar Abu Talib , Qassim Nasir , Yaman Afadar , Omar Elgendy

Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing…

Quantitative Methods · Quantitative Biology 2020-05-21 Xi Yang , Yan Gong , Nida Waheed , Keith March , Jiang Bian , William R. Hogan , Yonghui Wu

Melanoma is a prevalent lethal type of cancer that is treatable if diagnosed at early stages of development. Skin lesions are a typical indicator for diagnosing melanoma but they often led to delayed diagnosis due to high similarities of…

Machine Learning · Computer Science 2023-03-28 Ruitong Sun , Mohammad Rostami

Prostate cancer (PCa) is the most frequently diagnosed malignancy in men and the eighth leading cause of cancer death worldwide. Multiparametric MRI (mpMRI) has become central to the diagnostic pathway for men at intermediate risk,…

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States due to its five-year survival rate of 10%. Late diagnosis, affiliated with the asymptomatic nature in early stages and the location of the cancer with…

Quantitative Methods · Quantitative Biology 2020-12-15 Siya Goel , Clark Gedney , Jean Honorio

Deep neural networks are starting to show their worth in critical applications such as assisted cancer diagnosis. However, for their outputs to get accepted in practice, the results they provide should be explainable in a way easily…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Martin Krebs , Jan Obdržálek , Vít Musil , Tomáš Brázdil

Prostate cancer is one of the most common cancers in men. It is characterized by a slow growth and it can be diagnosed in an early stage by observing the Prostate Specific Antigen (PSA). However, a relapse after the primary therapy could…

Tissues and Organs · Quantitative Biology 2016-06-29 Emma Perracchione , Ilaria Stura

Skin cancer is the most common cancer worldwide, with melanoma being the deadliest form. Dermoscopy is a skin imaging modality that has shown an improvement in the diagnosis of skin cancer compared to visual examination without support. We…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Josef Steppan , Sten Hanke

Prostate and zonal segmentation is a crucial step for clinical diagnosis of prostate cancer (PCa). Computer-aided diagnosis tools for prostate segmentation are based on the deep learning (DL) paradigm. However, deep neural networks are…

Prostate cancer (PCa) remains a significant global health concern among men, particularly due to the lethality of its more aggressive variants. Despite therapeutic advancements that have enhanced survival for many patients, high grade PCa…

Quantitative Methods · Quantitative Biology 2025-10-15 Allison Powell , Paramahansa Pramanik

The presence of MGMT promoter methylation significantly affects how well chemotherapy works for patients with Glioblastoma Multiforme (GBM). Currently, confirmation of MGMT promoter methylation relies on invasive brain tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Rawan Alyahya , Asrar Alruwayqi , Atheer Alqarni , Asma Alkhaldi , Metab Alkubeyyer , Xin Gao , Mona Alshahrani

Non-invasive prostate cancer detection from MRI has the potential to revolutionize patient care by providing early detection of clinically-significant disease (ISUP grade group >= 2), but has thus far shown limited positive predictive…

Image and Video Processing · Electrical Eng. & Systems 2022-12-14 Abhejit Rajagopal , Antonio C. Westphalen , Nathan Velarde , Tim Ullrich , Jeffry P. Simko , Hao Nguyen , Thomas A. Hope , Peder E. Z. Larson , Kirti Magudia

The advent of digital pathology presents opportunities for computer vision for fast, accurate, and objective solutions for histopathological images and aid in knowledge discovery. This work uses deep learning to predict genomic biomarkers -…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Ruchi Chauhan , PK Vinod , CV Jawahar

Automatic diagnosis of malignant prostate cancer patients from mpMRI has been studied heavily in the past years. Model interpretation and domain drift have been the main road blocks for clinical utilization. As an extension from our…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Weiwei Zong , Eric Carver , Simeng Zhu , Eric Schaff , Daniel Chapman , Joon Lee , Hassan Bagher Ebadian , Indrin Chetty , Benjamin Movsas , Winston Wen , Tarik Alafif , Xiangyun Zong

Glioblastoma (GBM) is a highly aggressive primary brain tumor with limited therapeutic options and poor prognosis. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is a critical molecular biomarker…

Machine Learning · Computer Science 2026-01-13 Hasan M Jamil

Gene expression analysis is a critical method for cancer classification, enabling precise diagnoses through the identification of unique molecular signatures associated with various tumors. Identifying cancer-specific genes from gene…

Quantitative Methods · Quantitative Biology 2024-10-11 Farzana Tabassum , Sabrina Islam , Siana Rizwan , Masrur Sobhan , Tasnim Ahmed , Sabbir Ahmed , Tareque Mohmud Chowdhury