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Non-autoregressive (NAR) models generate all the tokens of a sequence in parallel, resulting in faster generation speed compared to their autoregressive (AR) counterparts but at the cost of lower accuracy. Different techniques including…

Computation and Language · Computer Science 2020-05-12 Yi Ren , Jinglin Liu , Xu Tan , Zhou Zhao , Sheng Zhao , Tie-Yan Liu

Spatial Transcriptomics (ST) offers spatially resolved gene expression but remains costly. Predicting expression directly from widely available Hematoxylin and Eosin (H&E) stained images presents a cost-effective alternative. However, most…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Jiarui Ouyang , Yihui Wang , Yihang Gao , Yingxue Xu , Shu Yang , Hao Chen

Diffusion-based models demonstrate impressive generation capabilities. However, they also have a massive number of parameters, resulting in enormous model sizes, thus making them unsuitable for deployment on resource-constraint devices.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Avideep Mukherjee , Soumya Banerjee , Piyush Rai , Vinay P. Namboodiri

In this paper, we have developed an approach to generate test data for path coverage based testing. The main challenge of this kind testing lies in its ability to build efficiently such a test suite in order to minimize the number of…

Software Engineering · Computer Science 2017-11-30 Esmaeel Nikravan , Farid Feyzi , Saeed Parsa

Autoregressive (AR) Large Language Models (LLMs) have demonstrated significant success across numerous tasks. However, the AR modeling paradigm presents certain limitations; for instance, contemporary autoregressive LLMs are trained to…

Machine Learning · Computer Science 2025-02-10 Justin Deschenaux , Caglar Gulcehre

Training robust learning algorithms across different medical imaging modalities is challenging due to the large domain gap. Unsupervised domain adaptation (UDA) mitigates this problem by using annotated images from the source domain and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Chen Li , Meilong Xu , Xiaoling Hu , Weimin Lyu , Chao Chen

Utilization of classification latent space information for downstream reconstruction and generation is an intriguing and a relatively unexplored area. In general, discriminative representations are rich in class-specific features but are…

Sequential dependencies present a fundamental bottleneck in deploying large-scale autoregressive models, particularly for real-time applications. While traditional optimization approaches like pruning and quantization often compromise model…

Computation and Language · Computer Science 2025-10-09 Yunhai Hu , Zining Liu , Zhenyuan Dong , Tianfan Peng , Bradley McDanel , Sai Qian Zhang

Sampling-based motion planning under task constraints is challenging because the null-measure constraint manifold in the configuration space makes rejection sampling extremely inefficient, if not impossible. This paper presents a…

Robotics · Computer Science 2022-04-15 Cihan Acar , Keng Peng Tee

This article makes discrete masked models for the generative modeling of discrete data controllable. The goal is to generate samples of a discrete random variable that adheres to a posterior distribution, satisfies specific constraints, or…

Machine Learning · Computer Science 2024-10-04 Wei Guo , Yuchen Zhu , Molei Tao , Yongxin Chen

Antimicrobial Resistance (AMR) is a rapidly escalating global health crisis. While genomic sequencing enables rapid prediction of resistance phenotypes, current computational methods have limitations. Standard machine learning models treat…

Machine Learning · Computer Science 2025-09-30 Md. Saiful Bari Siddiqui , Nowshin Tarannum

Dynamic magnetic resonance image reconstruction from incomplete k-space data has generated great research interest due to its capability to reduce scan time. Never-theless, the reconstruction problem is still challenging due to its…

Image and Video Processing · Electrical Eng. & Systems 2022-12-16 Chuanming Yu , Yu Guan , Ziwen Ke , Dong Liang , Qiegen Liu

Recent 3D molecular generation methods primarily use asynchronous auto-regressive or synchronous diffusion models. While auto-regressive models build molecules sequentially, they're limited by a short horizon and a discrepancy between…

Machine Learning · Computer Science 2026-04-27 Junyi An , Chao Qu , Yun-Fei Shi , Zhijian Zhou , Fenglei Cao , Yuan Qi

Current grammar-based NeuroEvolution approaches have several shortcomings. On the one hand, they do not allow the generation of Artificial Neural Networks (ANNs composed of more than one hidden-layer. On the other, there is no way to evolve…

Neural and Evolutionary Computing · Computer Science 2018-01-08 Filipe Assunção , Nuno Lourenço , Penousal Machado , Bernardete Ribeiro

This work presents RNAdiffusion, a latent diffusion model for generating and optimizing discrete RNA sequences of variable lengths. RNA is a key intermediary between DNA and protein, exhibiting high sequence diversity and complex…

Machine Learning · Computer Science 2024-10-03 Kaixuan Huang , Yukang Yang , Kaidi Fu , Yanyi Chu , Le Cong , Mengdi Wang

In single-cell research, tracing and analyzing high-throughput single-cell differentiation trajectories is crucial for understanding biological processes. Key to this is the robust modeling of hierarchical structures that govern cellular…

Machine Learning · Computer Science 2026-05-19 Zelin Zang , WenZhe Li , Yongjie Xu , Chang Yu , Changxi Chi , Jingbo Zhou , Zhen Lei , Stan Z. Li

Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of a given gene is heterogeneous both between cells and across time. We present a framework to model gene transcription in populations of cells…

Quantitative Methods · Quantitative Biology 2017-01-10 Justine Dattani , Mauricio Barahona

We introduce effective training algorithms for Generative Adversarial Networks (GAN) to alleviate mode collapse and gradient vanishing. In our system, we constrain the generator by an Autoencoder (AE). We propose a formulation to consider…

Computer Vision and Pattern Recognition · Computer Science 2018-12-18 Ngoc-Trung Tran , Tuan-Anh Bui , Ngai-Man Cheung

Diffusion models have shown remarkable performance in generation problems over various domains including images, videos, text, and audio. A practical bottleneck of diffusion models is their sampling speed, due to the repeated evaluation of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Taehong Moon , Moonseok Choi , EungGu Yun , Jongmin Yoon , Gayoung Lee , Jaewoong Cho , Juho Lee

Diffusion-based generative models learn to iteratively transfer unstructured noise to a complex target distribution as opposed to Generative Adversarial Networks (GANs) or the decoder of Variational Autoencoders (VAEs) which produce samples…

Machine Learning · Computer Science 2022-10-26 Sarthak Mittal , Guillaume Lajoie , Stefan Bauer , Arash Mehrjou
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