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Unsupervised Out-of-Distribution (OOD) detection consists in identifying anomalous regions in images leveraging only models trained on images of healthy anatomy. An established approach is to tokenize images and model the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Sergio Naval Marimont , Vasilis Siomos , Giacomo Tarroni

Detecting out-of-distribution (OOD) data has become a critical component in ensuring the safe deployment of machine learning models in the real world. Existing OOD detection approaches primarily rely on the output or feature space for…

Machine Learning · Computer Science 2021-10-12 Rui Huang , Andrew Geng , Yixuan Li

Deep learning models are increasingly deployed in safety-critical applications, where reliable out-of-distribution (OOD) detection is essential to ensure robustness. Existing methods predominantly rely on the penultimate-layer activations…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Shreen Gul , Mohamed Elmahallawy , Ardhendu Tripathy , Sanjay Madria

Existing out-of-distribution (OOD) detectors are often tuned by a separate dataset deemed OOD with respect to the training distribution of a neural network (NN). OOD detectors process the activations of NN layers and score the output, where…

Machine Learning · Computer Science 2026-02-06 Sudeepta Mondal , Xinyi Mary Xie , Ruxiao Duan , Alex Wong , Ganesh Sundaramoorthi

Out-of-distribution (OOD) detection is essential for deploying machine learning models in open-world and safety-critical scenarios, where test inputs may deviate from the training distribution and overconfident predictions on unknown…

Machine Learning · Computer Science 2026-05-28 Fengqiang Wan , Qing-Yuan Jiang , Yang Yang

Out-of-distribution (OOD) detection is crucial when deploying deep neural networks in the real world to ensure the reliability and safety of their applications. One main challenge in OOD detection is that neural network models often produce…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Jinlun Ye , Zhuohao Sun , Yiqiao Qiu , Qiu Li , Zhijun Tan , Ruixuan Wang

A straightforward pipeline for zero-shot out-of-distribution (OOD) detection involves selecting potential OOD labels from an extensive semantic pool and then leveraging a pre-trained vision-language model to perform classification on both…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Mengyuan Chen , Junyu Gao , Changsheng Xu

Out-of-distribution (OOD) detection is a crucial part of deploying machine learning models safely. It has been extensively studied with a plethora of methods developed in the literature. This problem is tackled with an OOD score…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Jingqiu Zhou , Aojun Zhou , Hongsheng Li

Neural networks are known to produce over-confident predictions on input images, even when these images are out-of-distribution (OOD) samples. This limits the applications of neural network models in real-world scenarios, where OOD samples…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Ke Fan , Yikai Wang , Qian Yu , Da Li , Yanwei Fu

Detecting out-of-distribution (OOD) inputs is crucial for the safe deployment of natural language processing (NLP) models. Though existing methods, especially those based on the statistics in the feature space of fine-tuned pre-trained…

Computation and Language · Computer Science 2023-01-31 Sishuo Chen , Wenkai Yang , Xiaohan Bi , Xu Sun

Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

Optics · Physics 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

Out-of-distribution (OOD) detection holds significant importance across many applications. While semantic and domain-shift OOD problems are well-studied, this work focuses on covariate shifts - subtle variations in the data distribution…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Francisco Caetano , Christiaan Viviers , Luis A. Zavala-Mondragón , Peter H. N. de With , Fons van der Sommen

The reliability of artificial intelligence (AI) systems in open-world settings depends heavily on their ability to flag out-of-distribution (OOD) inputs unseen during training. Recent advances in large-scale vision-language models (VLMs)…

Machine Learning · Computer Science 2025-10-14 Faizul Rakib Sayem , Shahana Ibrahim

Machine learning models are vulnerable to Out-Of-Distribution (OOD) examples, and such a problem has drawn much attention. However, current methods lack a full understanding of different types of OOD data: there are benign OOD data that can…

Machine Learning · Computer Science 2023-04-11 Zhuo Huang , Xiaobo Xia , Li Shen , Bo Han , Mingming Gong , Chen Gong , Tongliang Liu

Neural networks often make overconfident predictions from out-of-distribution (OOD) samples. Detection of OOD data is therefore crucial to improve the safety of machine learning. The simplest and most powerful method for OOD detection is…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Hikaru Shijo , Yutaka Yoshihama , Kenichi Yadani , Norifumi Murata

Out-of-distribution (OOD) detection aims to discern outliers from the intended data distribution, which is crucial to maintaining high reliability and a good user experience. Most recent studies in OOD detection utilize the information from…

Computation and Language · Computer Science 2022-10-21 Hyunsoo Cho , Choonghyun Park , Jaewook Kang , Kang Min Yoo , Taeuk Kim , Sang-goo Lee

How can models effectively detect out-of-distribution (OOD) samples in complex, multi-label settings without extensive retraining? Existing OOD detection methods struggle to capture the intricate semantic relationships and label…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Zhendong Liu , Yi Nian , Yuehan Qin , Henry Peng Zou , Li Li , Xiyang Hu , Yue Zhao

Obtaining accurate and valid information for drug molecules is a crucial and challenging task. However, chemical knowledge and information have been accumulated over the past 100 years from various regions, laboratories, and experimental…

Machine Learning · Computer Science 2023-10-12 Shuoying Wei , Xinlong Wen , Lida Zhu , Songquan Li , Rongbo Zhu

Deep learning has shown remarkable performance in medical image segmentation. However, despite its promise, deep learning has many challenges in practice due to its inability to effectively transition to unseen domains, caused by the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Dewei Hu , Hao Li , Han Liu , Jiacheng Wang , Xing Yao , Daiwei Lu , Ipek Oguz

Out-of-distribution (OOD) detection is a critical task for reliable predictions over text. Fine-tuning with pre-trained language models has been a de facto procedure to derive OOD detectors with respect to in-distribution (ID) data. Despite…

Computation and Language · Computer Science 2023-05-23 Rheeya Uppaal , Junjie Hu , Yixuan Li