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Recently we have extended our the "unified" model of evolutionary ecology to incorporate the {\it spatial inhomogeneities} of the eco-system and the {\it migration} of individual organisms from one patch to another within the same…

Populations and Evolution · Quantitative Biology 2009-11-10 Ambarish Kunwar

Statistical shape modeling (SSM) is widely used in biology and medicine as a new generation of morphometric approaches for the quantitative analysis of anatomical shapes. Technological advancements of in vivo imaging have led to the…

The field of mathematical morphology offers well-studied techniques for image processing. In this work, we view morphological operations through the lens of persistent homology, a tool at the heart of the field of topological data analysis.…

Computational Geometry · Computer Science 2021-03-25 Yu-Min Chung , Sarah Day , Chuan-Shen Hu

Human shape spaces have been extensively studied, as they are a core element of human shape and pose inference tasks. Classic methods for creating a human shape model register a surface template mesh to a database of 3D scans and use…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Stephan Wenninger , Fabian Kemper , Ulrich Schwanecke , Mario Botsch

We discuss general formation of complementary behaviors, functions and forms in biological species competing for resources. We call orthogonalization the related processes on macro and micro-level of a self-organized formation of…

Biological Physics · Physics 2007-05-23 Petr Kral

The tongue surface houses a range of papillae that are integral to the mechanics and chemistry of taste and textural sensation. Although gustatory function of papillae is well investigated, the uniqueness of papillae within and across…

Machine Learning · Computer Science 2023-12-15 Rayna Andreeva , Anwesha Sarkar , Rik Sarkar

We use topological data analysis and machine learning to study a seminal model of collective motion in biology [D'Orsogna et al., Phys. Rev. Lett. 96 (2006)]. This model describes agents interacting nonlinearly via attractive-repulsive…

Mimicry is a resemblance between species that benefits at least one of the species. It is a ubiquitous evolutionary phenomenon particularly common among prey species, in which case the advantage involves better protection from predation. We…

Populations and Evolution · Quantitative Biology 2011-08-09 Alexey Mikaberidze , Masudul Haque

We present a comprehensive study on discrete morphological symmetries of dynamical systems, which are commonly observed in biological and artificial locomoting systems, such as legged, swimming, and flying animals/robots/virtual characters.…

Robotics · Computer Science 2023-07-27 Daniel Ordonez-Apraez , Mario Martin , Antonio Agudo , Francesc Moreno-Noguer

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

We use topological data analysis as a tool to analyze the fit of mathematical models to experimental data. This study is built on data obtained from motion tracking groups of aphids in [Nilsen et al., PLOS One, 2013] and two random walk…

Quantitative Methods · Quantitative Biology 2018-11-13 M. Ulmer , Lori Ziegelmeier , Chad M. Topaz

We introduce a topology on the space of all isomorphism types represented in a given class of countable models, and use this topology as an aid in classifying the isomorphism types. This mixes ideas from effective descriptive set theory and…

Logic · Mathematics 2019-08-20 Russell Miller

The complexity of biological systems, and the increasingly large amount of associated experimental data, necessitates that we develop mathematical models to further our understanding of these systems. As biological systems are generally not…

Quantitative Methods · Quantitative Biology 2022-08-02 Sean T. Vittadello , Michael P. H. Stumpf

Bone remodeling is a complex process involving cell-cell interactions, biochemical signaling and mechanical stimuli. Early models of the biological aspects of remodeling were non-spatial and focused on the local dynamics at a fixed location…

Populations and Evolution · Quantitative Biology 2016-09-05 Marc D. Ryser , Kevin A. Murgas

In computer vision and medical imaging, the problem of matching structures finds numerous applications from automatic annotation to data reconstruction. The data however, while corresponding to the same anatomy, are often very different in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Pierre-Louis Antonsanti , Joan Glaunès , Thomas Benseghir , Vincent Jugnon , Irène Kaltenmark

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

A topological shape analysis is proposed and utilized to learn concepts that reflect shape commonalities. Our approach is two-fold: i) a spatial topology analysis of point cloud segment constellations within objects. Therein constellations…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Christian A. Mueller , Andreas Birk

The recent availability of larger typological databases such as Haspelmath et al. (2005) has brought the linguistics community closer to having a solid, empirical foundation for making actual claims about prehistoric migrations, deep…

Physics and Society · Physics 2007-05-23 Eric W. Holman , Christian Schulze , Dietrich Stauffer , Soren Wichmann

Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function. Here, we take a quantitative approach…

Tissues and Organs · Quantitative Biology 2023-02-07 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey