Related papers: PINNing Cerebral Blood Flow: Analysis of Perfusion…
Purpose: Arterial spin labeling (ASL) perfusion imaging indicates direct and absolute measurement of cerebral blood flow (CBF). Arterial transit time (ATT) is a related physiological parameter reflecting the duration for the labeled spins…
Arterial spin labeling (ASL) allows to quantify the cerebral blood flow (CBF) by magnetic labeling of the arterial blood water. ASL is increasingly used in clinical studies due to its noninvasiveness, repeatability and benefits in…
Physics-informed neural networks (PINNs) have shown promise in addressing the ill-posed deconvolution problem in computed tomography perfusion (CTP) imaging for acute ischemic stroke assessment. However, existing PINN-based approaches…
Purpose: Arterial Spin Labeling (ASL) is a quantitative, non-invasive alternative to perfusion imaging with contrast agents. Fixing values of certain model parameters in traditional ASL, which actually vary from region to region, may…
Arterial spin labeling perfusion MRI is a noninvasive technique for measuring quantitative cerebral blood flow (CBF), but the measurement is subject to a low signal-to-noise-ratio(SNR). Various post-processing methods have been proposed to…
Arterial Spin Labelling (ASL) functional Magnetic Resonance Imaging (fMRI) data provides a quantitative measure of blood perfusion, that can be correlated to neuronal activation. In contrast to BOLD measure, it is a direct measure of…
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is a powerful imaging technology that can measure cerebral blood flow (CBF) quantitatively. However, since only a small portion of blood is labeled compared to the whole tissue…
Perfusion MRI is an important modality in many brain imaging protocols, since it probes cerebrovascular changes in aging and many diseases; however, it may not be always available. Here we introduce a method that seeks to estimate regional…
Near-wall blood flow and wall shear stress (WSS) regulate major forms of cardiovascular disease, yet they are challenging to quantify with high fidelity. Patient-specific computational and experimental measurement of WSS suffers from…
Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…
Arterial spin labeling (ASL) perfusion MRI provides a non-invasive way to quantify cerebral blood flow (CBF) but it still suffers from a low signal-to-noise-ratio (SNR). Using deep machine learning (DL), several groups have shown…
Physics-informed neural networks (PINNs) have emerged as a powerful tool for solving inverse problems, especially in cases where no complete information about the system is known and scatter measurements are available. This is especially…
Ultrafast ultrasound blood flow imaging is a state-of-the-art technique for depiction of complex blood flow dynamics in vivo through thousands of full-view image data (or, timestamps) acquired per second. Physics-informed Neural Network…
This study introduces a computational approach leveraging Physics-Informed Neural Networks (PINNs) for the efficient computation of arterial blood flows, particularly focusing on solving the incompressible Navier-Stokes equations by using…
Accurate assessment of central hemodynamics is essential for diagnosis and risk stratification, yet it still relies largely on invasive measurements or on indirect reconstructions built from population-averaged transfer functions. While…
The placement of temperature sensitive and safety-critical components is crucial in the automotive industry. It is therefore inevitable, even at the design stage of new vehicles that these components are assessed for potential safety…
Tracer-kinetic models allow for the quantification of kinetic parameters such as blood flow from dynamic contrast-enhanced magnetic resonance (MR) images. Fitting the observed data with multi-compartment exchange models is desirable, as…
Due to the limited accuracy of 4D Magnetic Resonance Imaging (MRI) in identifying hemodynamics in cardiovascular diseases, the challenges in obtaining patient-specific flow boundary conditions, and the computationally demanding and…
Purpose: To develop biophysics-based method for estimating perfusion Q from arterial spin labeling (ASL) images using deep learning. Methods: A 3D U-Net (QTMnet) was trained to estimate perfusion from 4D tracer propagation images. The…
We develop a physics-informed neural network (PINN) to significantly augment state-of-the-art experimental data and apply it to stratified flows. The PINN is a fully-connected deep neural network fed with time-resolved, three-component…