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Sparse Autoencoders (SAEs) extract features from LLM internal activations, meant to correspond to interpretable concepts. A core SAE training hyperparameter is L0: how many SAE features should fire per token on average. Existing work…

Machine Learning · Computer Science 2025-12-08 David Chanin , Adrià Garriga-Alonso

Predicting protein function from amino acid sequence remains a central challenge in data-scarce (low-$N$) regimes, limiting machine learning-guided protein design when only small amounts of assay-labeled sequence-function data are…

Machine Learning · Computer Science 2025-08-27 Darin Tsui , Kunal Talreja , Amirali Aghazadeh

Instruction tuning data are often quantity-saturated due to the large volume of data collection and fast model iteration, leaving data selection important but underexplored. Existing quality-driven data selection methods, such as LIMA…

Computation and Language · Computer Science 2025-04-02 Xianjun Yang , Shaoliang Nie , Lijuan Liu , Suchin Gururangan , Ujjwal Karn , Rui Hou , Madian Khabsa , Yuning Mao

EEG foundation models achieve state-of-the-art clinical performance, yet the internal computations driving their predictions remain opaque: a barrier to clinical trust. We apply TopK Sparse Autoencoders (SAEs) across three architecturally…

Sparse autoencoders (SAEs) have received considerable recent attention as tools for mechanistic interpretability, showing success at extracting interpretable features even from very large LLMs. However, this research has been largely…

Machine Learning · Computer Science 2025-05-20 Jeremy Budd , Javier Ideami , Benjamin Macdowall Rynne , Keith Duggar , Randall Balestriero

Protein language models have revolutionized structure prediction, but their nonlinear nature obscures how sequence representations inform structure prediction. While sparse autoencoders (SAEs) offer a path to interpretability here by…

Biomolecules · Quantitative Biology 2025-03-13 Nithin Parsan , David J. Yang , John J. Yang

The ability of large language models (LLMs) to follow instructions is crucial for their practical applications, yet the underlying mechanisms remain poorly understood. This paper presents a novel framework that leverages sparse autoencoders…

Machine Learning · Computer Science 2025-02-18 Zirui He , Haiyan Zhao , Yiran Qiao , Fan Yang , Ali Payani , Jing Ma , Mengnan Du

Sparse autoencoders (SAEs) aim to disentangle model activations into monosemantic, human-interpretable features. In practice, learned features are often redundant and vary across training runs and sparsity levels, which makes…

Machine Learning · Computer Science 2026-01-01 Cristina P. Martin-Linares , Jonathan P. Ling

There is growing interest in leveraging mechanistic interpretability and controllability to better understand and influence the internal dynamics of large language models (LLMs). However, current methods face fundamental challenges in…

Computation and Language · Computer Science 2025-12-02 Ruben Härle , Felix Friedrich , Manuel Brack , Stephan Wäldchen , Björn Deiseroth , Patrick Schramowski , Kristian Kersting

Radiological services are experiencing unprecedented demand, leading to increased interest in automating radiology report generation. Existing Vision-Language Models (VLMs) suffer from hallucinations, lack interpretability, and require…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Ahmed Abdulaal , Hugo Fry , Nina Montaña-Brown , Ayodeji Ijishakin , Jack Gao , Stephanie Hyland , Daniel C. Alexander , Daniel C. Castro

Sparse autoencoders (SAEs) have been widely used for interpretability of neural networks, but their learned features often vary across seeds and hyperparameter settings. We introduce Ordered Sparse Autoencoders (OSAE), which extend…

Machine Learning · Computer Science 2025-12-03 Sophie L. Wang , Alex Quach , Nithin Parsan , John J. Yang

While sparse autoencoders (SAEs) successfully extract interpretable features from language models, applying them to audio generation faces unique challenges: audio's dense nature requires compression that obscures semantic meaning, and…

Machine Learning · Computer Science 2025-10-31 Nathan Paek , Yongyi Zang , Qihui Yang , Randal Leistikow

Sparse autoencoders (SAEs) have proven effective for extracting monosemantic features from large language models (LLMs), yet these features are typically identified in isolation. However, broad evidence suggests that LLMs capture the…

Artificial Intelligence · Computer Science 2026-02-13 Yifan Luo , Yang Zhan , Jiedong Jiang , Tianyang Liu , Mingrui Wu , Zhennan Zhou , Bin Dong

Large language models (LLMs) can store a significant amount of factual knowledge in their parameters. However, their parametric knowledge may conflict with the information provided in the context -- this phenomenon, known as…

Computation and Language · Computer Science 2025-02-11 Yu Zhao , Alessio Devoto , Giwon Hong , Xiaotang Du , Aryo Pradipta Gema , Hongru Wang , Xuanli He , Kam-Fai Wong , Pasquale Minervini

One of the roadblocks to a better understanding of neural networks' internals is \textit{polysemanticity}, where neurons appear to activate in multiple, semantically distinct contexts. Polysemanticity prevents us from identifying concise,…

Machine Learning · Computer Science 2023-10-05 Hoagy Cunningham , Aidan Ewart , Logan Riggs , Robert Huben , Lee Sharkey

Machine unlearning is a promising approach to improve LLM safety by removing unwanted knowledge from the model. However, prevailing gradient-based unlearning methods suffer from issues such as high computational costs, hyperparameter…

Machine Learning · Computer Science 2025-04-14 Aashiq Muhamed , Jacopo Bonato , Mona Diab , Virginia Smith

Sparse autoencoders (SAEs) promise a unified approach for mechanistic interpretability, concept discovery, and model steering in LLMs and LVLMs. However, realizing this potential requires learned features to be both interpretable and…

Machine Learning · Computer Science 2026-04-01 Akshay Kulkarni , Tsui-Wei Weng , Vivek Narayanaswamy , Shusen Liu , Wesam A. Sakla , Kowshik Thopalli

We present Universal Sparse Autoencoders (USAEs), a framework for uncovering and aligning interpretable concepts spanning multiple pretrained deep neural networks. Unlike existing concept-based interpretability methods, which focus on a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Harrish Thasarathan , Julian Forsyth , Thomas Fel , Matthew Kowal , Konstantinos G. Derpanis

Sparse autoencoders (SAEs) are widely used to extract sparse, interpretable latents from transformer activations. We test whether commonly used SAE quality metrics and automatic explanation pipelines can distinguish trained transformers…

Machine Learning · Computer Science 2026-01-28 Thomas Heap , Tim Lawson , Lucy Farnik , Laurence Aitchison

Recent work on sparse autoencoders (SAEs) has shown promise in extracting interpretable features from neural networks and addressing challenges with polysemantic neurons caused by superposition. In this paper, we apply SAEs to the early…

Machine Learning · Computer Science 2024-09-10 Liv Gorton