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A comprehensive understanding of molecular structures is important for the prediction of molecular ground-state conformation involving property information. Meanwhile, state space model (e.g., Mamba) has recently emerged as a promising…

Chemical Physics · Physics 2025-11-14 Yuxin Gou , Aming Wu , Richang Hong , Meng Wang

Mamba has garnered widespread attention due to its flexible design and efficient hardware performance to process 1D sequences based on the state space model (SSM). Recent studies have attempted to apply Mamba to the visual domain by…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Chengkun Wang , Wenzhao Zheng , Yuanhui Huang , Jie Zhou , Jiwen Lu

Molecular representation learning plays a crucial role in various downstream tasks, such as molecular property prediction and drug design. To accurately represent molecules, Graph Neural Networks (GNNs) and Graph Transformers (GTs) have…

Machine Learning · Computer Science 2025-02-07 Jingjing Hu , Dan Guo , Zhan Si , Deguang Liu , Yunfeng Diao , Jing Zhang , Jinxing Zhou , Meng Wang

DNA barcodes are crucial in biodiversity analysis for building automatic identification systems that recognize known species and discover unseen species. Unlike human genome modeling, barcode-based invertebrate identification poses…

Machine Learning · Computer Science 2024-12-17 Tiancheng Gao , Graham W. Taylor

We present PlainMamba: a simple non-hierarchical state space model (SSM) designed for general visual recognition. The recent Mamba model has shown how SSMs can be highly competitive with other architectures on sequential data and initial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Chenhongyi Yang , Zehui Chen , Miguel Espinosa , Linus Ericsson , Zhenyu Wang , Jiaming Liu , Elliot J. Crowley

Recent advancements in imitation learning, particularly with the integration of LLM techniques, are set to significantly improve robots' dexterity and adaptability. This paper proposes using Mamba, a state-of-the-art architecture with…

Robotics · Computer Science 2024-09-26 Toshiaki Tsuji

Recent advancements in State Space Models (SSMs) have attracted significant interest, particularly in models optimized for parallel training and handling long-range dependencies. Architectures like Mamba have scaled to billions of…

Machine Learning · Computer Science 2024-10-22 Zheng Zhan , Yushu Wu , Zhenglun Kong , Changdi Yang , Yifan Gong , Xuan Shen , Xue Lin , Pu Zhao , Yanzhi Wang

State space models (SSMs), such as Mamba, have emerged as an efficient alternative to transformers for long-context sequence modeling. However, despite their growing adoption, SSMs lack the interpretability tools that have been crucial for…

Computation and Language · Computer Science 2025-02-26 Hugo Pitorro , Marcos Treviso

Protein function prediction is a pivotal task in drug discovery, significantly impacting the development of effective and safe therapeutics. Traditional machine learning models often struggle with the complexity and variability inherent in…

Machine Learning · Computer Science 2024-09-24 Bohao Xu , Yingzhou Lu , Yoshitaka Inoue , Namkyeong Lee , Tianfan Fu , Jintai Chen

Mamba, a special case of the State Space Model, is gaining popularity as an alternative to template-based deep learning approaches in medical image analysis. While transformers are powerful architectures, they have drawbacks, including…

This paper examines the mathematical foundations of transformer architectures, highlighting their limitations particularly in handling long sequences. We explore prerequisite models such as Mamba, Vision Mamba (ViM), and LV-ViT that pave…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Ricky Fang

Mamba, with its selective State Space Models (SSMs), offers a more computationally efficient solution than Transformers for long-range dependency modeling. However, there is still a debate about its effectiveness in high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Chaohan Wang , Yutong Xie , Qi Chen , Yuyin Zhou , Qi Wu

Inspired by the recent success of the Mamba architecture in vision and language domains, we introduce a Unified Attention-Mamba (UAM) backbone. Unlike previous hybrid approaches that integrate Attention and Mamba modules in fixed…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Taixi Chen , Jingyun Chen , Nancy Guo

Transformers and Mamba, initially invented for natural language processing, have inspired backbone architectures for visual recognition. Recent studies integrated Local Attention Transformers with Mamba to capture both local details and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Meng Lou , Yunxiang Fu , Yizhou Yu

Vision Mamba has emerged as a promising and efficient alternative to Vision Transformers, yet its efficiency remains fundamentally constrained by the number of input tokens. Existing token reduction approaches typically adopt token pruning…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Shanhui Liu , Rui Xu , Yunke Wang

Computer-Aided Design (CAD) generative modeling has a strong and long-term application in the industry. Recently, the parametric CAD sequence as the design logic of an object has been widely mined by sequence models. However, the industrial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Xueyang Li , Yunzhong Lou , Yu Song , Xiangdong Zhou

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

Motivation: Generative models for protein backbone design have to simultaneously ensure geometric validity, sampling efficiency, and scalability to long sequences. However, most existing approaches rely on iterative refinement, quadratic…

Biomolecules · Quantitative Biology 2026-03-31 Tianyu Wu , Lin Zhu

Deep learning has achieved remarkable success in medical image segmentation, often reaching expert-level accuracy in delineating tumors and tissues. However, most existing approaches remain task-specific, showing strong performance on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Fares Bougourzi , Fadi Dornaika , Abdenour Hadid

Recently, the state space model Mamba has demonstrated efficient long-sequence modeling capabilities, particularly for addressing long-sequence visual tasks in 3D medical imaging. However, existing generative self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Fenghe Tang , Bingkun Nian , Yingtai Li , Zihang Jiang , Jie Yang , Wei Liu , S. Kevin Zhou
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