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In drug discovery, it is vital to confirm the predictions of pharmaceutical properties from computational models using costly wet-lab experiments. Hence, obtaining reliable uncertainty estimates is crucial for prioritizing drug molecules…

Machine Learning · Computer Science 2023-10-19 Siddhartha Laghuvarapu , Zhen Lin , Jimeng Sun

A novel framework for designing the molecular structure of chemical compounds with a desired chemical property has recently been proposed. The framework infers a desired chemical graph by solving a mixed integer linear program (MILP) that…

Computational Engineering, Finance, and Science · Computer Science 2023-05-02 Jianshen Zhu , Naveed Ahmed Azam , Kazuya Haraguchi , Liang Zhao , Hiroshi Nagamochi , Tatsuya Akutsu

This work addresses the challenge of training supervised machine or deep learning models on orbiting platforms where we are generally constrained by limited on-board hardware capabilities and restricted uplink bandwidths to upload. We aim…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Raúl Ramos-Pollán , Fabio A. González

We report an interpretation method for deep learning models that allows us to handle high-dimensional spectral data in materials science. The proposed method uses feature extraction and clustering analysis to categorize materials into…

Materials Science · Physics 2025-10-21 Akira Takahashi , Yu Kumagai , Arata Takamatsu , Fumiyasu Oba

The stable operation of autonomous off-grid photovoltaic systems requires solar forecasting algorithms that respect atmospheric thermodynamics. Contemporary deep learning models consistently exhibit critical anomalies, primarily severe…

Machine Learning · Computer Science 2026-04-21 Mohammed Ezzaldin Babiker Abdullah

We revisit the problem of computing the boundary density profile of a droplet of two-dimensional one-component plasma (2D OCP) with logarithmic interaction between particles in a confining harmonic potential. At a sufficiently low…

Statistical Mechanics · Physics 2020-12-30 Gabriel Cardoso , Jean-Marie Stéphan , Alexander G. Abanov

Octa-penta graphene (OPG), a novel carbon allotrope characterized by its distinctive arrangement of pentagonal and octagonal rings, has garnered considerable attention due to its exceptional structure and functional properties. This study…

Materials Science · Physics 2025-03-07 Chenyi Zhou , Rubin Huo , Boyi Situ , Zihan Yan , Zhe Zhang , Yusong Tu

In real-world environments, continual learning is essential for machine learning models, as they need to acquire new knowledge incrementally without forgetting what they have already learned. While pretrained language models have shown…

Machine Learning · Computer Science 2024-06-28 Mingyang Wang , Heike Adel , Lukas Lange , Jannik Strötgen , Hinrich Schütze

Uncertainty quantification (UQ) for open-ended language generation remains a critical yet underexplored challenge, especially under black-box constraints where internal model signals are inaccessible. In this paper, we introduce…

Computation and Language · Computer Science 2025-09-08 Beining Xu , Yongming Lu

In recent years the importance of Smart Healthcare cannot be overstated. The current work proposed to expand the state-of-art of smart healthcare in integrating solutions for Obsessive Compulsive Disorder (OCD). Identification of OCD from…

Organic molecular crystals underpin technologies ranging from pharmaceuticals to organic electronics, yet predicting solid-state packing of molecules remains challenging because candidate generation is combinatorial and stability is only…

Molecular Property Prediction (MPP) is vital for drug discovery, crop protection, and environmental science. Over the last decades, diverse computational techniques have been developed, from using simple physical and chemical properties and…

Machine Learning · Computer Science 2024-04-08 Afnan Sultan , Jochen Sieg , Miriam Mathea , Andrea Volkamer

The thermal conductivity of organic liquids is a vital parameter influencing various industrial and environmental applications, including energy conversion, electronics cooling, and chemical processing. However, atomistic simulation of…

In this article, a novel neuro-inspired low-resolution online unsupervised learning rule is proposed to train the reservoir or liquid of Liquid State Machine. The liquid is a sparsely interconnected huge recurrent network of spiking…

Neural and Evolutionary Computing · Computer Science 2016-04-20 Subhrajit Roy , Arindam Basu

Peptide compounds demonstrate considerable potential as therapeutic agents due to their high target affinity and low toxicity, yet their drug development is constrained by their low membrane permeability. Molecular weight and peptide length…

Machine Learning · Computer Science 2025-05-26 Shuang Wu , Meijie Wang , Lun Yu

In the realm of autonomous vehicle perception, comprehending 3D scenes is paramount for tasks such as planning and mapping. Camera-based 3D Semantic Occupancy Prediction (OCC) aims to infer scene geometry and semantics from limited…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Sanbao Su , Nuo Chen , Chenchen Lin , Felix Juefei-Xu , Chen Feng , Fei Miao

Water isotope separation, specifically separating heavy from light water, is a socially significant issue due to the usage of heavy water in applications such as nuclear magnetic resonance, nuclear power, and spectroscopy. Separation of…

Chemical Physics · Physics 2024-11-14 Jinu Jeong , Chenxing Liang , Narayana Aluru

Machine learning (ML) provides access to fast and accurate quantum chemistry (QC) calculations for various properties of interest such as excitation energies. It is often the case that high accuracy in prediction using an ML model, demands…

Chemical Physics · Physics 2024-03-13 Vivin Vinod , Ulrich Kleinekathöfer , Peter Zaspel

With the increasing use of large language models (LLMs) in daily life, concerns have emerged regarding their potential misuse and societal impact. Watermarking is proposed to trace the usage of specific models by injecting patterns into…

Cryptography and Security · Computer Science 2024-05-24 Baizhou Huang , Xiaojun Wan

The adoption of machine learning in materials science has rapidly transformed materials property prediction. Hurdles limiting full capitalization of recent advancements in machine learning include the limited development of methods to learn…

Machine Learning · Computer Science 2024-06-12 Shufeng Kong , Dan Guevarra , Carla P. Gomes , John M. Gregoire
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