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The emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of…

Genomics · Quantitative Biology 2025-01-28 Hadas Abraham , Barak Gahtan , Adir Kobovich , Orian Leitersdorf , Alex M. Bronstein , Eitan Yaakobi

Segment Anything Model (SAM) is an advanced foundational model for image segmentation, which is gradually being applied to remote sensing images (RSIs). Due to the domain gap between RSIs and natural images, traditional methods typically…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Nanqing Liu , Xun Xu , Yongyi Su , Haojie Zhang , Heng-Chao Li

Searching for similar genomic sequences is an essential and fundamental step in biomedical research and an overwhelming majority of genomic analyses. State-of-the-art computational methods performing such comparisons fail to cope with the…

Data Structures and Algorithms · Computer Science 2024-07-11 Mohammed Alser , Julien Eudine , Onur Mutlu

The Jaccard similarity index is an important measure of the overlap of two sets, widely used in machine learning, computational genomics, information retrieval, and many other areas. We design and implement SimilarityAtScale, the first…

Computational Engineering, Finance, and Science · Computer Science 2020-11-12 Maciej Besta , Raghavendra Kanakagiri , Harun Mustafa , Mikhail Karasikov , Gunnar Rätsch , Torsten Hoefler , Edgar Solomonik

High throughput sequencing of RNA (RNA-Seq) can provide us with millions of short fragments of RNA transcripts from a sample. How to better recover the original RNA transcripts from those fragments (RNA-Seq assembly) is still a difficult…

Genomics · Quantitative Biology 2019-02-15 Shunfu Mao , Yihan Jiang , Edwin Basil Mathew , Sreeram Kannan

Coherent optics has demonstrated significant potential as a viable solution for achieving 100 Gb/s and higher speeds in single-wavelength passive optical networks (PON). However, upstream burst-mode coherent detection is a major challenge…

Signal Processing · Electrical Eng. & Systems 2024-09-24 Yongxin Sun , Hexun Jiang , Yicheng Xu , Mengfan Fu , Yixiao Zhu , Lilin Yi , Weisheng Hu , Qunbi Zhuge

Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…

Machine Learning · Computer Science 2024-02-15 Ali Azizpour , Advait Balaji , Todd J. Treangen , Santiago Segarra

The problem of fast items retrieval from a fixed collection is often encountered in most computer science areas, from operating system components to databases and user interfaces. We present an approach based on hash tables that focuses on…

Neural and Evolutionary Computing · Computer Science 2020-07-17 Dan Domnita , Ciprian Oprisa

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

An applied problem facing all areas of data science is harmonizing data sources. Joining data from multiple origins with unmapped and only partially overlapping features is a prerequisite to developing and testing robust, generalizable…

Realizing the 6G vision of artificial intelligence (AI) and integrated sensing and communication (ISAC) critically requires large-scale real-world channel datasets for channel modeling and data-driven AI models. However, traditional…

Information Theory · Computer Science 2026-02-27 Yi Chen , Ming Li , Chong Han

Recursive query processing has experienced a recent resurgence, as a result of its use in many modern application domains, including data integration, graph analytics, security, program analysis, networking and decision making. Due to the…

Databases · Computer Science 2018-12-11 Zhiwei Fan , Jianqiao Zhu , Zuyu Zhang , Aws Albarghouthi , Paraschos Koutris , Jignesh Patel

Communication systems at millimeter-wave (mmW) and sub-terahertz frequencies are of increasing interest for future high-data rate networks. One critical challenge faced by phased array systems at these high frequencies is the efficiency of…

Signal Processing · Electrical Eng. & Systems 2022-02-18 Benjamin W. Domae , Ruifu Li , Danijela Cabric

The Segment Anything Model (SAM) family has become a widely adopted vision foundation model, but its ability to control segmentation granularity remains limited. Users often need to refine results manually - by adding more prompts or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Junwei Yu , Trevor Darrell , XuDong Wang

Understanding genetic variation, e.g., through mutations, in organisms is crucial to unravel their effects on the environment and human health. A fundamental characterization can be obtained by solving the haplotype assembly problem, which…

Genomics · Quantitative Biology 2022-10-25 Hansheng Xue , Vaibhav Rajan , Yu Lin

Next-generation particle accelerators demand advanced beam-diagnostic capabilities to ensure high performance, operational reliability, and sustainable machine operation. Increasing beam intensities and stored energies make the precise…

Accelerator Physics · Physics 2026-03-10 Francis René Osswald , Mohammed Chahbaoui , Xinyi Liang

Quantifying how hard it is to build a molecular graph matters for biosignature detection, chemical complexity, and cheminformatics. We present an exact, scalable algorithm to compute the molecular assembly index (MA) which prioritizes the…

Data Structures and Algorithms · Computer Science 2025-08-19 Ian Seet , Keith Y. Patarroyo , Gage Siebert , Sara I. Walker , Leroy Cronin

Unsupervised binary representation allows fast data retrieval without any annotations, enabling practical application like fast person re-identification and multimedia retrieval. It is argued that conflicts in binary space are one of the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-23 Fangrui Liu , Zheng Liu

The de novo assembly of large, complex genomes is a significant challenge with currently available DNA sequencing technology. While many de novo assembly software packages are available, comparatively little attention has been paid to…

Genomics · Quantitative Biology 2013-07-31 Jared T. Simpson

Traditional radar sensing typically involves matched filtering between the received signal and the shape of the transmitted pulse. Under the confinement of classic sampling theorem this requires that the received signals must first be…

Information Theory · Computer Science 2013-07-09 Eliahu Baransky , Gal Itzhak , Idan Shmuel , Noam Wagner , Eli Shoshan , Yonina C. Eldar
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