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Large language models (LLMs) show promise in healthcare, but hallucinations remain a major barrier to clinical use. We present CHECK, a continuous-learning framework that integrates structured clinical databases with a classifier grounded…

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

Large language models (LLMs) are increasingly applied in clinical decision support, yet current evaluations rarely reveal whether their outputs reflect genuine medical reasoning or superficial correlations. We introduce DeVisE (Demographics…

Computation and Language · Computer Science 2026-02-27 Camila Zurdo Tagliabue , Heloisa Oss Boll , Aykut Erdem , Erkut Erdem , Iacer Calixto

Large language models (LLMs) have been widely adopted due to their remarkable performance across various applications, driving the accelerated development of a large number of diverse models. However, these individual LLMs show limitations…

Computation and Language · Computer Science 2025-06-13 Kaushal Kumar Maurya , KV Aditya Srivatsa , Ekaterina Kochmar

This paper introduces an innovative framework designed for progressive (granular in time to onset) prediction of seizures through the utilization of a Deep Learning (DL) methodology based on non-invasive multi-modal sensor networks.…

Signal Processing · Electrical Eng. & Systems 2024-11-05 Ali Saeizadeh , Douglas Schonholtz , Joseph S. Neimat , Pedram Johari , Tommaso Melodia

Early recognition of clinical deterioration is one of the main steps for reducing inpatient morbidity and mortality. The challenging task of clinical deterioration identification in hospitals lies in the intense daily routines of healthcare…

Background: Circadian desynchrony characterized by the misalignment between an individual's internal biological rhythms and external environmental cues, significantly affects various physiological processes and health outcomes. Quantifying…

With the increasing availability of patient data, modern medicine is shifting towards prospective healthcare. Electronic health records offer a variety of information useful for clinical patient characterization and the development of…

Machine Learning · Computer Science 2025-05-27 Fabio Azzalini , Tommaso Dolci , Marco Vagaggini

Recent large language models (LLMs) have demonstrated the ability to perform explicit multi-step reasoning such as chain-of-thought prompting. However, their intermediate steps often contain errors that can propagate leading to inaccurate…

Artificial Intelligence · Computer Science 2025-08-06 Yijin Yang , Cristina Cornelio , Mario Leiva , Paulo Shakarian

Digital health interventions increasingly deliver home exercise programs via sensor-equipped devices such as smartphones, enabling remote monitoring of adherence and performance. However, current software is usually authored before clinical…

Large Language Model (LLM) inference on large-scale systems is expected to dominate future cloud infrastructures. Efficient LLM inference in cloud environments with numerous AI accelerators is challenging, necessitating extensive…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-11 Ilias Bournias , Lukas Cavigelli , Georgios Zacharopoulos

The association between preoperative cognitive status and surgical outcomes is a critical, yet scarcely explored area of research. Linking intraoperative data with postoperative outcomes is a promising and low-cost way of evaluating…

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare,…

Artificial Intelligence · Computer Science 2025-02-27 Guoxin Wang , Minyu Gao , Shuai Yang , Ya Zhang , Lizhi He , Liang Huang , Hanlin Xiao , Yexuan Zhang , Wanyue Li , Lu Chen , Jintao Fei , Xin Li

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

With the rapid development of cloud computing systems and the increasing complexity of their infrastructure, intelligent mechanisms to detect and mitigate failures in real time are becoming increasingly important. Traditional methods of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-20 Cheng Ji , Huaiying Luo

Large language models (LLMs) are prone to hallucinations, i.e., nonsensical, unfaithful, and undesirable text. Users tend to overrely on LLMs and corresponding hallucinations which can lead to misinterpretations and errors. To tackle the…

Human-Computer Interaction · Computer Science 2024-05-22 Florian Leiser , Sven Eckhardt , Valentin Leuthe , Merlin Knaeble , Alexander Maedche , Gerhard Schwabe , Ali Sunyaev

Uncertainty estimation is a necessary component when implementing AI in high-risk settings, such as autonomous cars, medicine, or insurances. Large Language Models (LLMs) have seen a surge in popularity in recent years, but they are subject…

Machine Learning · Computer Science 2024-12-09 Gabriel Y. Arteaga , Thomas B. Schön , Nicolas Pielawski

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

Computers and Society · Computer Science 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo