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Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in breast cancer screening, tumor assessment, and treatment planning and monitoring. The dynamic changes in contrast in different tissues help to…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Rui Wang , Yuexi Du , John Lewin , R. Todd Constable , Nicha C. Dvornek

Diffusing-Wave Spectroscopy (DWS) treats the transport of photons through turbid samples as a diffusion process, thereby making it possible to extract the dynamics of scatterers from measured correlation functions. The analysis of DWS data…

Soft Condensed Matter · Physics 2017-12-27 Zahra Fahimi , Frank Aangenendt , Panayiotis Voudouris , Johan Mattson , Hans M. Wyss

We present Distortion-Guided Restoration (DGR), a physics-informed hybrid CNN-diffusion framework for acquisition-free correction of severe susceptibility-induced distortions in prostate single-shot EPI diffusion-weighted imaging (DWI). DGR…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Ziyang Long , Binesh Nader , Lixia Wang , Archana Vadiraj Malaji , Chia-Chi Yang , Haoran Sun , Rola Saouaf , Timothy Daskivich , Hyung Kim , Yibin Xie , Debiao Li , Hsin-Jung Yang

Diffusion Weighted Imaging (DWI) is an advanced imaging technique commonly used in neuroscience and neurological clinical research through a Diffusion Tensor Imaging (DTI) model. Volumetric scalar metrics including fractional anisotropy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Zihao Tang , Xinyi Wang , Lihaowen Zhu , Mariano Cabezas , Dongnan Liu , Michael Barnett , Weidong Cai , Chengyu Wang

Double diffusion encoding (DDE) makes diffusion MRI sensitive to a wide range of microstructural features, and the acquired data can be analysed using different approaches. Correlation tensor imaging (CTI) uses DDE to resolve three…

Medical Physics · Physics 2024-12-05 Arthur Chakwizira , Filip Szczepankiewicz , Markus Nilsson

The displacement distribution of a water molecular is characterized mathematically as Gaussianity without considering potential diffusion barriers and compartments. However, this is not true in real scenario: most biological tissues are…

Computation · Statistics 2015-07-27 Jia Liu

In this work, the blood NIR absorbances are recorded using the FT-IR method. It is shown that when the absorbance curves are multiplied by the first derivative of the water absorbance spectrum as well as by the first derivative of the…

Medical Physics · Physics 2025-07-22 Hadi Barati , Arian Mousavi Madani , Soheil Moradi , Mehdi Fardmanesh

A new sequence for single-voxel diffusion-weighted 1H MRS (DWS), named DW-SPECIAL, is proposed to improve the detection and subsequent estimation of the diffusion properties of strongly J-coupled metabolites. It combines the semi-adiabatic…

Medical Physics · Physics 2023-11-21 Jessie Mosso , Dunja Simicic , Bernard Lanz , Rolf Gruetter , Cristina Cudalbu

Diffusion-weighted magnetic resonance imaging (DW-MRI) is used to characterize brain tissue microstructure employing tissue-specific biophysical models. A current limitation, however, is that most of the proposed models are based on the…

Introduction: Quantification of dynamic contrast-enhanced (DCE)-MRI has the potential to provide valuable clinical information, but robust pharmacokinetic modeling remains a challenge for clinical adoption. Methods: A 7-layer neural network…

Medical Physics · Physics 2024-05-22 Ouri Cohen , Soudabeh Kargar , Sungmin Woo , Alberto Vargas , Ricardo Otazo

Purpose: Free water elimination diffusion tensor imaging (FWE-DTI) has been widely used to distinguish increases of free water (FW) partial volume effects from tissue's diffusion in healthy ageing and degenerative diseases. Since the…

Medical Physics · Physics 2021-07-20 Marc Golub , Rafael Neto Henriques , Rita G. Nunes

Brain tumors present a grave risk to human life, demanding precise and timely diagnosis for effective treatment. Inaccurate identification of brain tumors can significantly diminish life expectancy, underscoring the critical need for…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Md. Alamin Talukder , Md. Manowarul Islam , Md Ashraf Uddin

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Xingda Li

Ultrasound Localization Microscopy (ULM) relies on the injection of microbubbles (MBs) to obtain highly resolved density maps of blood circulation in vivo, with a resolution that can reach 10 {\mu}m ~ {\lambda}/10 in the rodent brain.…

Noninvasive, non-contact and \textit{in vivo} monitoring of blood glucose is a long needed pathology tool for saving patients from recurring pain and hassle that can accompany conventional blood glucose testing methods. Optical coherence…

Biological Physics · Physics 2008-08-04 R Poddar , S R Sharma , P Sen , J T Andrews

Double diffusion encoding (DDE) magnetic resonance measurements of the water signal offers a unique ability to separate the effect of microscopic anisotropic diffusion in structural units of tissue from the overall macroscopic orientational…

Medical Physics · Physics 2020-12-04 Henrik Lundell , Chloé Najac , Marjolein Bulk , Hermien E. Kan , Andrew G. Webb , Itamar Ronen

Recently, there has been interest in determining the viscoelastic properties of polymeric liquids and other complex fluids by means of Diffusing Wave Spectroscopy (DWS). In this technique, light-scattering spectroscopy is applied to highly…

Soft Condensed Matter · Physics 2024-08-27 George D. J. Phillies

Quantitative information on tumor heterogeneity and cell load could assist in designing effective and refined personalized treatment strategies. It was recently shown by us that such information can be inferred from the diffusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Yi Yin , Kai Breuhahn , Hans-Ulrich Kauczor , Oliver Sedlaczek , Irene E. Vignon-Clementel , Dirk Drasdo

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Diffusion-weighted imaging (DWI) is a powerful non-invasive tool which is widely used in clinical routine. Mostly, apparent diffusion coefficient maps are acquired, which cannot be directly related to cellular structure. More recently it…