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First-principles-based modelings have been extremely successful in providing crucial insights and predictions for complex biological functions and phenomena. However, they can be hard to build and expensive to simulate for complex living…

Adaptation and Self-Organizing Systems · Physics 2024-11-26 Ruilin Zhang , Zhongyi Wang , Tianyi Wu , Yuhang Cai , Louis Tao , Zhuo-Cheng Xiao , Yao Li

Synaptic plasticity and neuron cross-talk are some of the important key mechanisms underlying formation of dynamic clusters of active neurons. The essence of this study is to model and decipher the mechanism of emergence of a task-specific…

Neurons and Cognition · Quantitative Biology 2021-08-03 Jasleen Gund , R. K. Brojen Singh

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses…

Neurons and Cognition · Quantitative Biology 2014-12-23 Gabriel Koch Ocker , Ashok Litwin-Kumar , Brent Doiron

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

In the context of multi-agent systems of binary interacting particles, a kinetic model for action potential dynamics on a neural network is proposed, accounting for heterogeneity in the neuron-to-neuron connections, as well as in the brain…

Biological Physics · Physics 2026-02-24 Marzia Bisi , Martina Conte , Maria Groppi

This paper describes how realistic neuromorphic networks can have their connectivity properties fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa

Building upon the findings presented in the first three papers of this series, we formulate an effective field theory for interacting collective states. These states consist of a large number of interconnected neurons and are distinguished…

Biological Physics · Physics 2024-05-22 Pierre Gosselin , Aïleen Lotz

In this paper, we propose a framework to control brain-wide functional connectivity by selectively acting on the brain's structure and parameters. Functional connectivity, which measures the degree of correlation between neural activities…

Systems and Control · Computer Science 2020-03-17 Tommaso Menara , Giacomo Baggio , Danielle S. Bassett , Fabio Pasqualetti

Theoretical models of neuronal function consider different mechanisms through which networks learn, classify and discern inputs. A central focus of these models is to understand how associations are established amongst neurons, in order to…

Neurons and Cognition · Quantitative Biology 2015-05-19 Harold P. de Vladar , Eörs Szathmáry

Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

The primate heteromodal cortex presents an evident functional modularity at a mesoscopic level, with physiological and anatomical evidence pointing to it as likely substrate of long-term memory. In order to investigate some of its…

Neurons and Cognition · Quantitative Biology 2021-12-09 Carlo Fulvi Mari

We demonstrate that the dynamics of neural networks trained with gradient descent and the dynamics of scalar fields in a flat, vacuum energy dominated Universe are structurally profoundly related. This duality provides the framework for…

General Relativity and Quantum Cosmology · Physics 2022-02-24 Sven Krippendorf , Michael Spannowsky

Contact Hamiltonian dynamics is a subject that has still a short history, but with relevant applications in many areas: thermodynamics, cosmology, control theory, and neurogeometry, among others. In recent years there has been a great…

Mathematical Physics · Physics 2021-02-23 Manuel de León , Manuel Lainz

How can a collection of motile cells, each generating contractile nematic stresses in isolation, become an extensile nematic at the tissue-level? Understanding this seemingly contradictory experimental observation, which occurs irrespective…

Soft Condensed Matter · Physics 2022-02-21 Andrew Killeen , Thibault Bertrand , Chiu Fan Lee

The performance of attractor neural networks has been shown to depend crucially on the heterogeneity of the underlying topology. We take this analysis a step further by examining the effect of degree-degree correlations -- or assortativity…

Disordered Systems and Neural Networks · Physics 2015-05-20 Sebastiano de Franciscis , Samuel Johnson , Joaquín J. Torres

The neuronal circuit that controls obsessive and compulsive behaviors involves a complex network of brain regions (some with known involvement in reward processing). Among these are cortical regions, the striatum and the thalamus (which…

Neurons and Cognition · Quantitative Biology 2015-12-17 Anca Radulescu , Rachel Marra

Action-dependent field theories are systems where the Lagrangian or Hamiltonian depends on new variables that encode the action. They model a larger class of field theories, including non-conservative behavior, while maintaining a…

High Energy Physics - Theory · Physics 2025-05-01 Manuel de León , Jordi Gaset Rifà , Miguel C. Muñoz-Lecanda , Xavier Rivas , Narciso Román-Roy

Mathematical modelling of the macroscopic electrical activity of the brain is highly non-trivial and requires a detailed understanding of not only the associated mathematical techniques, but also the underlying physiology and anatomy.…

Neurons and Cognition · Quantitative Biology 2023-06-22 Blake J. Cook , Andre D. H. Peterson , Wessel Woldman , John R. Terry

Dynamical mean-field theory is a powerful physics tool used to analyze the typical behavior of neural networks, where neurons can be recurrently connected, or multiple layers of neurons can be stacked. However, it is not easy for beginners…

Disordered Systems and Neural Networks · Physics 2024-02-21 Wenxuan Zou , Haiping Huang

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh