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We propose a diffusion-based framework for prompt optimization that leverages Diffusion Language Models (DLMs) to iteratively refine system prompts through masked denoising. By conditioning on interaction traces, including user queries,…

Computation and Language · Computer Science 2026-02-24 Shiyu Wang , Haolin Chen , Liangwei Yang , Jielin Qiu , Rithesh Murthy , Ming Zhu , Zixiang Chen , Silvio Savarese , Caiming Xiong , Shelby Heinecke , Huan Wang

Diffusion Language Models (DLMs) offer a promising alternative for language modeling by enabling parallel decoding through iterative refinement. However, most DLMs rely on hard binary masking and discrete token assignments, which hinder the…

Computation and Language · Computer Science 2026-01-19 Linhao Zhong , Linyu Wu , Bozhen Fang , Tianjian Feng , Chenchen Jing , Wen Wang , Jiaheng Zhang , Hao Chen , Chunhua Shen

Drug discovery can be viewed as a combinatorial search over an immense chemical space, motivating the development of deep generative models for de novo molecular design. Among these, GPT-based molecular language models (MLM) have shown…

Machine Learning · Computer Science 2026-02-02 Qianwei Yang , Dong Xu , Zhangfan Yang , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji

Fashion content generation is an emerging area at the intersection of artificial intelligence and creative design, with applications ranging from virtual try-on to culturally diverse design prototyping. Existing methods often struggle with…

Computation and Language · Computer Science 2025-01-28 Spencer Ramsey , Amina Grant , Jeffrey Lee

Recently, diffusion models have excelled in image generation tasks and have also been applied to neural language processing (NLP) for controllable text generation. However, the application of diffusion models in a cross-lingual setting is…

Computation and Language · Computer Science 2023-08-01 Linyao Chen , Aosong Feng , Boming Yang , Zihui Li

Microstructure plays a critical role in determining the macroscopic properties of materials, with applications spanning alloy design, MEMS devices, and tissue engineering, among many others. Computational frameworks have been developed to…

Computational Engineering, Finance, and Science · Computer Science 2024-09-24 Nikita Kartashov , Nikolaos N. Vlassis

Recent Speech Large Language Models~(LLMs) have achieved impressive capabilities in end-to-end speech interaction. However, the prevailing autoregressive paradigm imposes strict serial constraints, limiting generation efficiency and…

Computation and Language · Computer Science 2026-02-10 Ziyang Cheng , Yuhao Wang , Heyang Liu , Ronghua Wu , Qunshan Gu , Yanfeng Wang , Yu Wang

Protein language models (pLMs) have demonstrated success at generating functional proteins across vast sequence spaces but lack the ability to design high-fitness variants on demand. Here, we iteratively guide pLMs toward user-defined…

Biomolecules · Quantitative Biology 2025-12-01 Filippo Stocco , Maria Artigues-Lleixa , Andrea Hunklinger , Talal Widatalla , Marc Guell , Noelia Ferruz

Protein language models (PLMs) encode rich biological information, yet their internal neuron representations are poorly understood. We introduce the first automated framework for labeling every neuron in a PLM with biologically grounded…

Machine Learning · Computer Science 2025-07-10 Arjun Banerjee , David Martinez , Camille Dang , Ethan Tam

Machine Learning-guided solutions for protein learning tasks have made significant headway in recent years. However, success in scientific discovery tasks is limited by the accessibility of well-defined and labeled in-domain data. To tackle…

Machine Learning · Computer Science 2023-01-06 Ria Vinod , Pin-Yu Chen , Payel Das

Masked diffusion language models (MDLMs) generate text via iterative masked-token denoising, enabling mask-parallel decoding and distinct controllability and efficiency tradeoffs from autoregressive LLMs. Yet, efficient representation-level…

Computation and Language · Computer Science 2026-03-31 Adi Shnaidman , Erin Feiglin , Osher Yaari , Efrat Mentel , Amit Levi , Raz Lapid

Diffusion Language Models (DLMs) provide a promising alternative to autoregressive language models by generating text through iterative denoising and bidirectional refinement. However, this iterative generation paradigm also introduces…

Computation and Language · Computer Science 2026-05-14 Yejin Lee , Yo-Sub Han

This paper introduces a discrete diffusion model (DDM) framework for text-aligned speech tokenization and reconstruction. By replacing the auto-regressive speech decoder with a discrete diffusion counterpart, our model achieves…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-25 Pin-Jui Ku , He Huang , Jean-Marie Lemercier , Subham Sekhar Sahoo , Zhehuai Chen , Ante Jukić

Diffusion-based models have shown great promise in molecular generation but often require a large number of sampling steps to generate valid samples. In this paper, we introduce a novel Straight-Line Diffusion Model (SLDM) to tackle this…

Machine Learning · Computer Science 2025-06-10 Yuyan Ni , Shikun Feng , Haohan Chi , Bowen Zheng , Huan-ang Gao , Wei-Ying Ma , Zhi-Ming Ma , Yanyan Lan

We introduce the hfut-lmc team's solution to the SLRTP Sign Production Challenge. The challenge aims to generate semantically aligned sign language pose sequences from text inputs. To this end, we propose a Text-driven Diffusion Model (TDM)…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Jiayi He , Xu Wang , Ruobei Zhang , Shengeng Tang , Yaxiong Wang , Lechao Cheng

Recently, prompt tuning \cite{lester2021power} has gradually become a new paradigm for NLP, which only depends on the representation of the words by freezing the parameters of pre-trained language models (PLMs) to obtain remarkable…

Computation and Language · Computer Science 2022-01-31 Pan He , Yuxi Chen , Yan Wang , Yanru Zhang

Controlling the behavior of language models (LMs) without re-training is a major open problem in natural language generation. While recent works have demonstrated successes on controlling simple sentence attributes (e.g., sentiment), there…

Computation and Language · Computer Science 2022-05-31 Xiang Lisa Li , John Thickstun , Ishaan Gulrajani , Percy Liang , Tatsunori B. Hashimoto

Unified architectures in multimodal large language models (MLLM) have shown promise in handling diverse tasks within a single framework. In the text-to-speech (TTS) task, current MLLM-based approaches rely on discrete token representations,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-27 Xinlu He , Swayambhu Nath Ray , Harish Mallidi , Jia-Hong Huang , Ashwin Bellur , Chander Chandak , M. Maruf , Venkatesh Ravichandran

By formulating data samples' formation as a Markov denoising process, diffusion models achieve state-of-the-art performances in a collection of tasks. Recently, many variants of diffusion models have been proposed to enable controlled…

Machine Learning · Computer Science 2023-04-17 Hengtong Zhang , Tingyang Xu

In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li