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Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Quantum information processing offers dramatic speedups, yet is famously susceptible to decoherence, the process whereby quantum superpositions decay into mutually exclusive classical alternatives, thus robbing quantum computers of their…

Quantum Physics · Physics 2014-08-21 Kristen L. Pudenz , Tameem Albash , Daniel A. Lidar

The problem of selecting an appropriate number of features in supervised learning problems is investigated in this paper. Starting with common methods in machine learning, we treat the feature selection task as a quadratic unconstrained…

Quantum Physics · Physics 2023-06-21 Gerhard Hellstern , Vanessa Dehn , Martin Zaefferer

In the rapidly advancing domain of quantum optimization, the confluence of quantum algorithms such as Quantum Annealing (QA) and the Quantum Approximate Optimization Algorithm (QAOA) with robust optimization methodologies presents a…

Quantum Physics · Physics 2024-05-14 Pascal Halffmann , Steve Lenk , Michael Trebing

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

An AI-powered quality engineering platform uses artificial intelligence to boost software quality assessments through automated defect prediction and optimized performance alongside improved feature extraction. Existing models result in…

Artificial Intelligence · Computer Science 2025-03-21 Seshu Babu Barma , Mohanakrishnan Hariharan , Satish Arvapalli

The recent advent of commercially available quantum annealing hardware (QAH) has expanded opportunities for research into quantum annealing-based algorithms. In the domain of power systems, this advancement has driven increased interest in…

Optimization and Control · Mathematics 2025-03-26 Rosemary Barrass , Harsha Nagarajan , Carleton Coffrin

Quantum annealing has emerged as a powerful tool for solving combinatorial optimization problems efficiently, making use of the principles of quantum mechanics. Companies are increasingly investing in the market of quantum computers,…

Quantum Physics · Physics 2025-09-29 Lorenzo Mazzei , Giada Beccari , Mirko Laruina , Marco Cococcioni

Quantum computation offers exciting new possibilities for statistics. This paper explores the use of the D-Wave machine, a specialized type of quantum computer, which performs quantum annealing. A general description of quantum annealing…

Computation · Statistics 2019-11-21 Robert C. Foster , Brian Weaver , James Gattiker

Current quantum neural networks suffer from extreme sensitivity to both adversarial perturbations and hardware noise, creating a significant barrier to real-world deployment. Existing robustness techniques typically sacrifice clean accuracy…

Quantum Physics · Physics 2026-01-27 Mohamed Afane , Quanjiang Long , Haoting Shen , Ying Mao , Junaid Farooq , Ying Wang , Juntao Chen

Hard Attention Mechanisms (HAMs) effectively filter essential information discretely and significantly boost the performance of machine learning models on large datasets. Nevertheless, they confront the challenge of non-differentiability,…

Quantum Physics · Physics 2024-12-31 Ren-Xin Zhao

Quantum annealing is a promising paradigm for building practical quantum computers. Compared to other approaches, quantum annealing technology has been scaled up to a larger number of qubits. On the other hand, deep learning has been…

Quantum Physics · Physics 2021-07-07 Michele Sasdelli , Tat-Jun Chin

Quantum annealing allows for quantum fluctuations to be used used to assist in finding the solution to some of the worlds most challenging computational problems. Recently, this field has attracted much interest because of the construction…

Quantum Physics · Physics 2022-07-26 Nicholas Chancellor

Combining quantum computers with classical compute power has become a standard means for developing algorithms that are eventually supposed to beat any purely classical alternatives. While in-principle advantages for solution quality or…

Quantum Physics · Physics 2026-01-23 Simon Thelen , Wolfgang Mauerer

Maintaining software quality is crucial in the dynamic landscape of software development. Regression testing ensures that software works as expected after changes are implemented. However, re-executing all test cases for every modification…

Software Engineering · Computer Science 2025-01-29 Antonio Trovato , Manuel De Stefano , Fabiano Pecorelli , Dario Di Nucci , Andrea De Lucia

Quantum-classical hybrid algorithms offer a promising strategy for tackling computationally challenging problems, such as the maximum independent set (MIS) problem that plays a crucial role in areas like network design and data analysis.…

Quantum Physics · Physics 2025-06-17 Seokho Jeong , Juyoung Park , Jaewook Ahn

Quantum annealing is getting increasing attention in combinatorial optimization. The quantum processing unit by D-Wave is constructed to approximately solve Ising models on so-called Chimera graphs. Ising models are equivalent to quadratic…

Data Structures and Algorithms · Computer Science 2019-04-30 Michael Juenger , Elisabeth Lobe , Petra Mutzel , Gerhard Reinelt , Franz Rendl , Giovanni Rinaldi , Tobias Stollenwerk

The D-Wave adiabatic quantum annealer solves hard combinatorial optimization problems leveraging quantum physics. The newest version features over 1000 qubits and was released in August 2015. We were given access to such a machine,…

Databases · Computer Science 2015-10-23 Immanuel Trummer , Christoph Koch

Digital-analog quantum computing (DAQC) offers a promising approach to addressing the challenges of building a practical quantum computer. By efficiently allocating resources between digital and analog quantum circuits, DAQC paves the way…

Quantum Physics · Physics 2024-04-08 Tadashi Kadowaki

Recent work has shown that quantum annealing for machine learning, referred to as QAML, can perform comparably to state-of-the-art machine learning methods with a specific application to Higgs boson classification. We propose QAML-Z, a…

Quantum Physics · Physics 2021-01-04 Alexander Zlokapa , Alex Mott , Joshua Job , Jean-Roch Vlimant , Daniel Lidar , Maria Spiropulu
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