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We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early…

Liver fibrosis represents the accumulation of excessive extracellular matrix caused by sustained hepatic injury. It disrupts normal lobular architecture and function, increasing the chances of cirrhosis and liver failure. Precise staging of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Yang Zhou , Kunhao Yuan , Ye Wei , Jishizhan Chen

Liver cirrhosis, a leading cause of global mortality, requires precise segmentation of ROIs for effective disease monitoring and treatment planning. Existing segmentation models often fail to capture complex feature interactions and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Vandan Gorade , Onkar Susladkar , Gorkem Durak , Elif Keles , Ertugrul Aktas , Timurhan Cebeci , Alpay Medetalibeyoglu , Daniela Ladner , Debesh Jha , Ulas Bagci

Liver cirrhosis is an insidious condition involving the substitution of normal liver tissue with fibrous scar tissue and causing major health complications. The conventional method of diagnosis using liver biopsy is invasive and, therefore,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Kapil Kashyap , Sean Fargose , Chrisil Dabre , Fatema Dolaria , Nilesh Patil , Aniket Kore

Liver fibrosis poses a substantial challenge in clinical practice, emphasizing the necessity for precise liver segmentation and accurate disease staging. Based on the CARE Liver 2025 Track 4 Challenge, this study introduces a multi-task…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and the most common cause of death of people suffering from cirrhosis. The segmentation of liver lesions in CT images allows assessment of tumor load,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Nadja Gruber , Stephan Antholzer , Werner Jaschke , Christian Kremser , Markus Haltmeier

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

Liver lesion segmentation is an important step for liver cancer diagnosis, treatment planning and treatment evaluation. LiTS (Liver Tumor Segmentation Challenge) provides a common testbed for comparing different automatic liver lesion…

Computer Vision and Pattern Recognition · Computer Science 2017-07-05 Xiao Han

Segmentation of medical images is a challenging task owing to their complexity. A standard segmentation problem within Magnetic Resonance Imaging (MRI) is the task of labeling voxels according to their tissue type. Image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2013-04-02 G. Geethu Lakshmi

Accurate analysis of the fibrosis stage plays very important roles in follow-up of patients with chronic hepatitis B infection. In this paper, a deep learning framework is presented for automatically liver fibrosis prediction. On contrary…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Jiali Liu , Wenxuan Wang , Tianyao Guan , Ningbo Zhao , Xiaoguang Han , Zhen Li

We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion…

Computer Vision and Pattern Recognition · Computer Science 2017-03-21 Assaf Hoogi , John W. Lambert , Yefeng Zheng , Dorin Comaniciu , Daniel L. Rubin

Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Bowen Li , Ke Yan , Dar-In Tai , Yuankai Huo , Le Lu , Jing Xiao , Adam P. Harrison

Primary tumors have a high likelihood of developing metastases in the liver and early detection of these metastases is crucial for patient outcome. We propose a method based on convolutional neural networks (CNN) to detect liver metastases.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Mariëlle J. A. Jansen , Hugo J. Kuijf , Maarten Niekel , Wouter B. Veldhuis , Frank J. Wessels , Max A. Viergever , Josien P. W. Pluim

Colorectal liver metastasis is one of most aggressive liver malignancies. While the definition of lesion type based on CT images determines the diagnosis and therapeutic strategy, the discrimination between cancerous and non-cancerous…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Francisco Perdigon Romero , Andre Diler , Gabriel Bisson-Gregoire , Simon Turcotte , Real Lapointe , Franck Vandenbroucke-Menu , An Tang , Samuel Kadoury

Background & Aims: Hepatic steatosis is a major cause of chronic liver disease. 2D ultrasound is the most widely used non-invasive tool for screening and monitoring, but associated diagnoses are highly subjective. We developed a scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Bowen Li , Dar-In Tai , Ke Yan , Yi-Cheng Chen , Shiu-Feng Huang , Tse-Hwa Hsu , Wan-Ting Yu , Jing Xiao , Le Lu , Adam P. Harrison

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Peilong Wang , Timothy L. Kline , Andy D. Missert , Cole J. Cook , Matthew R. Callstrom , Alex Chan , Robert P. Hartman , Zachary S. Kelm , Panagiotis Korfiatis

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Spiculations/lobulations, sharp/curved spikes on the surface of lung nodules, are good predictors of lung cancer malignancy and hence, are routinely assessed and reported by radiologists as part of the standardized Lung-RADS clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Wookjin Choi , Navdeep Dahiya , Saad Nadeem

Precise segmentation of the liver is critical for computer-aided diagnosis such as pre-evaluation of the liver for living donor-based transplantation surgery. This task is challenging due to the weak boundaries of organs, countless…

Image and Video Processing · Electrical Eng. & Systems 2021-09-06 Supriti Mulay , Deepika G , Jeevakala S , Keerthi Ram , Mohanasankar Sivaprakasam

In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Patrick Bilic , Patrick Christ , Hongwei Bran Li , Eugene Vorontsov , Avi Ben-Cohen , Georgios Kaissis , Adi Szeskin , Colin Jacobs , Gabriel Efrain Humpire Mamani , Gabriel Chartrand , Fabian Lohöfer , Julian Walter Holch , Wieland Sommer , Felix Hofmann , Alexandre Hostettler , Naama Lev-Cohain , Michal Drozdzal , Michal Marianne Amitai , Refael Vivantik , Jacob Sosna , Ivan Ezhov , Anjany Sekuboyina , Fernando Navarro , Florian Kofler , Johannes C. Paetzold , Suprosanna Shit , Xiaobin Hu , Jana Lipková , Markus Rempfler , Marie Piraud , Jan Kirschke , Benedikt Wiestler , Zhiheng Zhang , Christian Hülsemeyer , Marcel Beetz , Florian Ettlinger , Michela Antonelli , Woong Bae , Míriam Bellver , Lei Bi , Hao Chen , Grzegorz Chlebus , Erik B. Dam , Qi Dou , Chi-Wing Fu , Bogdan Georgescu , Xavier Giró-i-Nieto , Felix Gruen , Xu Han , Pheng-Ann Heng , Jürgen Hesser , Jan Hendrik Moltz , Christian Igel , Fabian Isensee , Paul Jäger , Fucang Jia , Krishna Chaitanya Kaluva , Mahendra Khened , Ildoo Kim , Jae-Hun Kim , Sungwoong Kim , Simon Kohl , Tomasz Konopczynski , Avinash Kori , Ganapathy Krishnamurthi , Fan Li , Hongchao Li , Junbo Li , Xiaomeng Li , John Lowengrub , Jun Ma , Klaus Maier-Hein , Kevis-Kokitsi Maninis , Hans Meine , Dorit Merhof , Akshay Pai , Mathias Perslev , Jens Petersen , Jordi Pont-Tuset , Jin Qi , Xiaojuan Qi , Oliver Rippel , Karsten Roth , Ignacio Sarasua , Andrea Schenk , Zengming Shen , Jordi Torres , Christian Wachinger , Chunliang Wang , Leon Weninger , Jianrong Wu , Daguang Xu , Xiaoping Yang , Simon Chun-Ho Yu , Yading Yuan , Miao Yu , Liping Zhang , Jorge Cardoso , Spyridon Bakas , Rickmer Braren , Volker Heinemann , Christopher Pal , An Tang , Samuel Kadoury , Luc Soler , Bram van Ginneken , Hayit Greenspan , Leo Joskowicz , Bjoern Menze
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